Prion Disease Round Table 2003 REVISITED AUGUST 2010

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Sunday, August 29, 2010


Prion Disease Round Table Conducted Wednesday December 11, 2003 at Denver, Colorado R-CALF-USA Sponsored (REVISITED AUGUST 2010)


From: Terry S. Singeltary Sr.

Sent: Sunday, August 29, 2010 11:49 AM

Subject: Prion Disease Round Table Conducted Wednesday December 11, 2003 at Denver, Colorado R-CALF-USA Sponsored (REVISITED AUGUST 2010)

Greetings,

Below is the full text (unedited version) of the Prion Round Table Conducted Wednesday December 11, 2003 at Denver, Colorado R-CALF-USA Sponsored (REVISITED AUGUST 2010 by me). Periodically, I will comment on science that has changed since this Prion Round Table, and will reference the update scientific data. So the full text of the 2003 PRION ROUND TABLE IS HERE, but is broke up intermittently with my comments and updated scientific facts. It is interested for sure, to see the thought process in 2003 by the Government and the Industry, and compare to today. The ever emerging TSE science is changing, mutating and becoming more virulent, but sadly, the SSS policy is still going strong in the USA. OF course, Canada is finding cases, they are the only ones searching for cases in North America. Ramifications from all this, human TSE i.e. CJD and the new prionopathy there from is on the rise. ...TSS

Prion Disease Round Table Conducted Wednesday December 11, 2003 at Denver, Colorado R-CALF-USA Sponsored (REVISITED AUGUST 2010)

R-CALF-USA Sponsored Prion Disease Round Table Conducted Wednesday December 11, 2003 at Denver, Colorado

On Thursday, December 11, 2003, R-CALF-USA and a number of its affiliate cattle organizations sponsored a Prion Disease Roundtable in Denver, Colorado. Dr. R. M. Thornsberry, President of the Missouri Stockgrower’s Association was commissioned by R-CALF President Leo McDonnel to organize the roundtable and invite prion specialists to present information at the roundtable that would benefit the education of livestock producers throughout the United States.

Dr. Stanley Prusiner, the scientist who discovered prions, for which he won the Nobel Prize in medicine, was invited to the roundtable. Notes from Dr. Prusiner’s presentation on prions and prion diseases were presented to the roundtable by Dr. Thornsberry, who had attended one of Dr. Prusiner’s lectures on prion diseases. Although unable to attend the roundtable, Dr. Prusiner provided the roundtable with five papers published in prestigious peer reviewed medical and science journals. These papers were provided to all the attendees and key points from these papers were discussed at the beginning of the roundtable discussion. Dr. Prusiner emphasized normal cooking temperatures do not inactivate prions. This point is especially important when humans are exposed to Bovine Spongiform Encephalopathy (BSE) prions in the normal process of consuming beef muscle cuts that may contain significant nerve tissue. Dr. Prusiner’s laboratory is currently developing a live animal test to determine whether or not an animal is carrying BSE prions prior to entering the food chain for human consumption.

Dr. Jason Bartz, an applied science researcher from Creighton University, Omaha, Nebraska, was the second presenter at the roundtable. Dr. Bartz presented current research data on prion diseases and particularly outlined the pathogenesis of prion diseases. Dr. Bartz presented data that defined the ability of prions to replicate in secondary lymphoreticular system tissues, and the ability of prions to travel throughout the nervous system, finally locating within the brain or brain stem tissues where pathological changes occur. Dr. Bartz also presented data to illustrate the severity of prion disease appears to increase as the disease is passed from animal to animal. Dr. Bartz presented data to illustrate the infectivity and persistency of prions. Prions in brain tissue were heated to 600 degrees Celsius--that is over 1200 degrees Fahrenheit--and injected into brain tissue. These heat treated prions were still capable of causing prion disease changes. In other words, there is no commonly utilized method with which to inactivate prions on surgical instruments, surfaces, pens, corrals, chutes, ground, etc. Dr. Bartz also presented data that indicates tongue lesions or sores provide the mechanism for prions to enter brain tissue through the nerve that supplies the muscle tissue of an animal’s tongue. ...snip...end...(TSS/2010)

Completely Edited Version

PRION ROUNDTABLE


snip...see full text ;


http://bseusa.blogspot.com/2010/08/prion-disease-round-table-conducted.html


TSS