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More than 5 million have Alzheimer's in U.S. - Alzheimer's Disease ...
updated 6:15 p.m. ET March 18, 2008. WASHINGTON - An estimated 5.2 million Americans have Alzheimer’s disease, and it could steal the minds of one out of ...
www.msnbc.msn.com/id/23697160/ - 49k - Cached - Similar pages - Note this

5% x 5.2 MILLION = 260,000


ALZHEIMER’S = between 2 and 25% actually have sCJD


The statistical incidence of CJD cases in the United States has been revised to reflect that there is one case per 9000 in adults age 55 and older. Eighty-five percent of the cases are sporadic, meaning there is no known cause at present.

http://www.cjdfoundation.org/fact.html



“Human victims of sCreutzfeldt Jakob Disease (CJD) are also shedding infectious prions into public sewers, to end up in both Class B and Class A sludge compost. Between 2 and 25% of the 4.5 million cases of Alzheimer’s Disease and senile dementia victims in the US are actually infected with sporadic CJD. (Manuelidis, et al, 1989; Bendixen, 1996; Boller, et al, 1989, 1995; Harrison, 1991; Teixeira, 1995; Warren, et al, 2005) “

The hidden incidence of CJD
http://www.mad-cow.org/jan_11_98_news.html#hidden

Dr. Birgitte Bendixen, assistant professor in the University of Iowa College of Medicine's Department of Neurology has been quoted as stating in 1996
'When we do autopsies, we find that five of every 100 people who have been diagnosed with Alzheimer's had CJD,''
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Creutzfeldt-Jakob Disease (CJD) affects both men and women worldwide usually between the ages of 50 to 75 years. The officially stated mortality rate is one to two deaths per one million population per year. However, this figure appears to be an understatement as CJD is often misdiagnosed. A study performed at the University of Pittsburgh showed over 5% of Alzheimer's patients were actually CJD victims
http://www.zarcrom.com/users/alzheimers/odem/cjd1.html

In a study by Yale University researchers found that 13% of Alzheimers patients were found upon autopsy to actually have CJD. (Dr. Laura Manuelidis, et al http://www.cyber-dyne.com/~tom/Alzheimer_cjd.html#clinical

Teixeira, et al, found 3 out of 12 AD patients were really suffering from CJD. (25% ) Teixeira, F., et al. “Clinico-Pathological Correlation in Dementias.” Journal of Psychiatry and Neuroscience 20 (1995): 276-282.


“ . . . a study at the University of Pittsburgh, in which autopsies were done on 54 demented patients diagnosed as having probable or possible Alzheimer's or some other dementia (but not CJD), found 3 cases (or 5.5%) of CJD among the 54 studied (Boller et al., 1989).

Furthermore, research by Dr. Laura Manuelidis, head of neuropathology at Yale University found that as many as 13% of Alzheimer patients actually die of CJD. (Alzheimer Disease and Associated Disorders, Vol 3 Nos 1-2 1989).

The American Council on Science and Health estimates there are 5 million Alzheimer victims in the United States. http://www.acsh.org/publications/booklets/alzheimers2002.html
Using the lower figure of 5%, this means there may be up to 250,000 victims of CJD/prion disease in the US at the present time. Thus, there could be a hidden CJD epidemic. (See accompanying file on CJD which notes several clusters and victims under 55 years of age.)


Prions have been found in the blood and urine of CJD victims. (Gabizon, et al, 2001; Reichl, et al 2002) . Undertakers and medical facilities routinely discharge CJD infected blood and body fluids into public sewers. (Yale; UC Davis, CDC)

Prions can cross the intestinal barrier by riding piggyback on ferritin, a protein normally absorbed by the intestine. Because ferritin shares considerable homology across species, these data suggest that PrPSc-associated proteins, in particular ferritin, may facilitate PrPSc uptake in the intestine from distant species, leading to a carrier state in humans. (Singh, et al 2004)

“ . . . enteric infection at early as well as later stages of (CJD) disease, and regardless of the route of agent entry, implicates potential environmental spread by fecal matter.” (Radebold, et al 2001)



Radebold K, Chernyak M, Martin D, Manuelidis L. 2001.Blood borne transit of CJD from brain to gut at early stages of infection. BMC Infect Dis 1:20–25.



Journal of Cellular Biochemistry 9999:1–19 (2006) PROSPECT A 25 nm Virion Is the Likely Cause of Transmissible Spongiform Encephalopathies

Laura Manuelidis* Yale Medical School, New Haven, Connecticut 06510

Page 2 - "

"The observation that infected blood carries the infectious agent to the intestinal tract, a direction opposite to that commonly assumed, also raises the likelihood of shedding these infectious agents in feces, with further environmental contamination [Radebold et al., 2001]. This is a common mode of spread for many viruses such as the enteroviruses and hepatitis B. "
************************************************************

"The Journal of Infectious Diseases 2008;198:81–89 © 2008 by the Infectious
Diseases Society of America. All rights reserved.
0022-1899/2008/19801-0015$15.00 DOI: 10.1086/588193

MAJOR ARTICLE

Transmission and Detection of Prions in Feces

Jiri G. Safar,1,2 Pierre Lessard,1 Gültekin Tamgüney,1,2 Yevgeniy Freyman,1 Camille Deering,1 Frederic Letessier,1 Stephen J. DeArmond,1,3 and Stanley
B. Prusiner1,2,4

Incubation times of 140 days and a rate of prion infection of 80%-100% among exposed animals suggested transmission
by feces, probably via coprophagy. (eating feces)

" Our findings suggest that horizontal transmission of disease among herbivores may occur through the consumption of feces or
foodstuff tainted with prions from feces of CWD-infected cervids and scrapie-infected sheep.

********************************************************

"Prions can cross the intestinal barrier by riding piggyback on ferritin, a protein normally absorbed by the intestine. Because ferritin shares considerable homology across species, these data suggest that PrPSc-associated proteins, in particular ferritin, may facilitate PrPSc uptake in the intestine from distant species, leading to a carrier state in humans. (Singh, et al 2004)"

“ . . . enteric infection at early as well as later stages of (CJD) disease, and regardless of the route of agent entry, implicates potential environmental spread by fecal matter.” (Radebold, et al 2001)"

******************************************************************

Soil amplification of infectivity by a factor of almost 700 is particularly significant when you consider how small an infective dose is:

USDA/APHIS "The significance of small amounts of infectivity become evident when you consider that experimentally it has been shown that exposure of sensitive species to as little as 1.0, 0.1 or even 0.01 grams of infected nervous tissue can induce infection. "

"Given all of the above (except complete burning in closed furnaces), it must be recognized that no process has been demonstrated to be 100 % effective in removing TSE infectivity and there will be some residual levels of infectivity remaining after treatment."

http://www.aphis.usda.gov/NCIE/oie/rtf_files/tahc-carcass-disp-jan05.rtf "]
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Alzheimer's and CJD
A clinical series with 13% of Alzheimer actually CJD ..... diagnosed with dementia were actually dying from Creutzfeldt-Jakob disease (Boller, 1989). ...
www.mad-cow.org/Alzheimer_cjd.html - 33k - Cached - Similar pages - Note this
More Evidence Mad Cow Same As CJD And Alzheimer's
I have posted some data below on CJD and Alzheimer's that you may find ..... Boller F. Cognitive deficits and clinical diagnosis of Alzheimer's disease. ...
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Alzheimer's And CJD Scientifically Linked
The most common misdiagnosis of CJD is Alzheimer's disease (Harrison, 1991). ... Boller, F., O. L. Lopez, and J. Moossy. "Diagnosis of Dementia. ...
www.rense.com/general46/alz.html - 20k - Cached - Similar pages - Note this

Alzheimer's and CJD
A clinical series with 13% of Alzheimer actually CJD ..... 3 out of 12 "Alzheimer" patients actually died from a spongiform encephalopathy (Teixeira, 1995). ...
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Could Mad Cow Disease Already be Killing Thousands of Americans ...
[55] Neither CJD nor Alzheimer's can be conclusively diagnosed without a brain ..... 67 Teixeira, F., et al. "Clinico-Pathological Correlation in Dementias. ...
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Alzheimer's And CJD Scientifically Linked
The most common misdiagnosis of CJD is Alzheimer's disease (Harrison, 1991). ... patients actually died from a spongiform encephalopathy (Teixeira, 1995). ...
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http://www.mad-cow.org/Alzheimer_cjd.html

The true prevalence of prion diseases in this or any other country remains a mystery (Harrison, 1991). Compounding the uncertainty, autopsies are rarely performed on atypical dementias (Harrison, 1991), because medical professionals fear infection (Altman, 1996a). The officially reported rate in this country is less than 1 case in a million people per year (World, 1996). An informal survey of neuropathologists, however, registered a theoretical range of 2-12% of all dementias as actually CJD (Harrison, 1991). And hundreds of thousands of Americans suffer from severe dementias every year (Brayne, 1994; United, 1995). Two other studies average about a 3% CJD rate among dementia patients (Mahendra, 1987; Wade, 1987). A preliminary 1989 University of Pennsylvania study showed that 5% of patients diagnosed with dementia were actually dying from Creutzfeldt-Jakob disease (Boller, 1989). It would seem CJD is seriously underdiagnosed at present (Harrison, 1991).





CJD Facts
... 13% of Alzheimer patients were found upon autopsy to actually have CJD. .... Sporadic CJD may develop because some of a person’s normal prions ...
members.aol.com/larmstr853/cjdvoice/facts.htm - 35k - Cached - Similar pages - Note this

www.vegetablekillers.net - Mad Cow, Alzheimer's and CJD
Dec 3, 2006 ... Vegetable Killers - a veggie forum, Mad Cow, Alzheimer's and CJD ... the dead were actually CJD cases misdiagnosed as Alzheimer's disease. ...
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Alzheimer's and CJD
A clinical series with 13% of Alzheimer actually CJD ..... Prusiner, S. Some Speculations about Prions, Amyloid, and Alzheimer's Disease. ...
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CJD buried in Alzheimer
So now the argument is that CJD, as buried in Alzheimers, might also have been undergoing a marked rate increase for the last decade or two, and account for ...
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Every 72 seconds someone in America develops Alzheimer’s
Do you agree with colm kelleher where he states there may be a relationship between vCJD and alzeheimer's in that alzheimers may be misdiagnosed. ...
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VegSource Article
When researchers studied the brains of dead Alzheimer’s disease patients, ... of these people actually have CJD, not AD, then CJD is much more common than ...
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Mad Cow Disease and Alzheimer's -- Is there a connection?
"We don’t know exactly what’s happening to the rate of CJD in this country, ... North Americans with Alzheimer’s-like symptoms might actually have CJD. ...
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