I've owned this car for 12 yrs and have run E10 pretty much exclusively putting about 40K miles on it in that time. Car has about 112K on it now so it's fairly low mileage for a 27 yr old car!

Might dump a can of Sea Foam in the tank before storing for the off-season as the last few years I have parked the car from Oct-May. Only drive it in the months I figure I'll need the AC! (BTW, the AC still can freeze me out with good ol' R12. I got the AC serviced right after I bought the car.)
I figure the fuel system has to be pretty clean from continuously running E10 already. There can't be much junk to cut loose in there unless I ran into a bad tank of fuel somewhere.
I have changed a fuel pump or two before on this car, along with my other Chevy small blocks. I blame poor quality fuel pump mfg, not ethanol for premature pump failures I have experienced. Very seldom has a mechanical engine cam driven fuel pump left me stranded, most times they just leak gas externally. An internal leak into the engine would be a problem but fortunately I've never had that happen. My '79 Impala once left me sitting along the road when the spring on the fuel pump cam lever broke. Certainly not the fault of the fuel.
Of course this car is not rated for E85. I doubt E10 ethanol fuel was even widely available as a commercial fuel when this car was manufactured. It would be easy to carry and change an inline fuel filter on this car as there is already is one installed between the fuel pump and carb. The factory filter is where the fuel line goes into the carb.