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ITEM 6 – BARB CASE CLUSTERS

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flounder

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ITEM 6 – BARB CASE CLUSTERS

39. Professor John Wilesmith (Defra) updated the committee on the

BSE cases born after the 1996 reinforced mammalian meat and

bone meal ban in the UK (BARB cases). Around 116 BARB cases

had been identified in Great Britain up to 22 November 2005,

mostly through active surveillance. BARB cases had decreased in

successive birth cohorts, from 44 in the 1996/1997 cohort to none

to date in the 2000/2001 cohort. However, 3 BARB cases had

been identified in the 2001/2002 cohort. Backcalculation of the

prevalence of BARB cases indicated a drop from 130 infected

animals per million (95% confidence interval 90-190) in the

1996/1997 cohort to 30 infected animals per million (95%

confidence interval 10-60) in the 1999/2000 cohort. A shift in the

geographical distribution of BSE cases, from the concentration of

pre-1996 BSE cases in Eastern England to a more uniform

14

© SEAC 2005

distribution of BARB cases, had occurred. However, it appeared

that certain post-1996 cohorts had a higher exposure to BSE in

certain areas for limited periods. Several clusters of BARB cases

within herds had been identified (5 pairs, 2 triplets and 1

quadruplet).

40. A triplet of BARB cases in South West Wales had been

investigated in detail. The triplet comprised 2 cases born in

September and October 2001 and a third in May 2002. The

animals born in 2001 were reared outdoors from the spring of 2002

but the animal born in 2002 had been reared indoors. Further

investigation of feeding practices revealed that a new feed bin for

the adult dairy herd had been installed in September 1998. In July

2002 the feed bin was emptied, but not cleaned, and relocated. All

3 BARB cases received feed from the relocated bin. This finding

suggested the hypothesis that the feed bin installed in September

1998 was filled initially with contaminated feed, that remnants of

this feed fell to the bottom of the bin during its relocation, and thus

young animals in the 2001/2002 birth cohort were exposed to

feedstuffs produced in 1998. No adult cattle had been infected

because of the reduced susceptibility to BSE with increasing age.

41. Further investigation of multiple case herds had found no

association of BARB clusters with the closure of feed mills.

42. Professor Wilesmith concluded that there is evidence of a decline

in risk of infection for successive birth cohorts of cattle. The BARB

epidemic is unlikely to be sustained by animals born after 31 July

2000. Feed bins could represent a continued source of occasional

infection and advice to farmers is being formulated to reduce this

risk. There is no evidence for an indigenous source of infection for

the BARB cases.

43. Members considered it encouraging that no other factor, apart from

feed contamination, had been identified as a possible cause of

BARB cases to date. Members commented that this study

suggests that only a small amount of contaminated feed may be

required for infection and that BSE infectivity can survive in the

environment for several years. Professor Wilesmith agreed and

noted that infection caused by small doses of infectious material

was consistent with other studies, and it would appear there is little

dilution of infectivity, if present, in the rendering system.

Additionally it appeared that the infectious agent had survived for 4

years in the feed bin.

44. The Chair thanked Professor Wilesmith for his presentation.



snip...



http://www.seac.gov.uk/minutes/final90.pdf


TSS
 

Econ101

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This parallels the antibiotic resistant bacteria studies by Johns Hopkins that found antibiotic resistant strains long after the use of antibiotics was stopped in poultry operations.

It is very concerning. Flounder, could you please define BARB? I can assume what it means by the context but it would be nice to know from you.
 

flounder

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Cases of BSE in cows born after the 1996 reinforced feed ban are known as BARB cases. ...TSS
 

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