Greetings Ranchers et al,
i am living proof of antibiotic resistant infection, i.e. MRSA, 7+ weeks 1000 to 1250 mgs vancomycin straight to the heart via longline PIC. nasty stuff. this time around, i will tell them to dip me in monkey blood, with follow-up bath in 100% bleach ;-) yep, a few disposable tools and grinder, no cadaver bone and or blood, all my own, just to make sure no friendly fire from TSE, and what the hell do you suppose happened, yep, they infect me with another super bug, MRSA. THAT was Dec. 2001. since then, a new super bug that is resistant to even vancomycin. this is called VRSA, and trust me, you do not want to tango with that one, and i will throw the dice again soon. you just never know, and i know more than i ever wanted too. all i wanted was a fat juicy steak and a cold beer... that was long ago, things have changed since the good old days. ...TSS
here are a few warning letters for just this past week ;
WARNING LETTER
2006-DT-22
May 9,2006
Mr. Kenneth L. Wagler
Wagler Farms
7085 Homestead Road
Morgantown, IN 46160
Dear Mr. Wagler:
An inspection of your dairy. operation located at 7085 Homestead Road, Morgantown, Indiana 46160, conducted by a representative of the Food and Drug Administration (FDA) on November 1418, 2005, confirmed that you offered an animal for sale for slaughter as food that was adulterated under section 402(a)(2)(C)(ii) [21 U.S.C. § 342(a)(2)(C)(ii)] of the Federal Food, Drug, and Cosmetic Act (the Act).You can find the Act and its associated regulations on the Internet through links of FDA's web page at www.fda.gov.
On September 13, 2005, you, sold a bull identified with back tag number 32UP 9127 through [redacted] to [redacted] then delivered the bull to [redacted] where, it was slaughtered for human food use on September 15, 2005. United States Department of Agriculture, Food Safety Inspection Service (USDA/FSIS) analysis of tissue samples collected from this animal identified the presence of [redacted] (ppm) gentamicin in the kidney of this bull. No tolerance of gentamicin has been established for residues of gentamicin in the edible tissues of cattle as codified in Title 21, Code of Federal Regulations (21 C.F.R.), Part 556.300 (21 C.F.R 556.300). In addition, USDA/FSIS analysis of tissue samples collected from this animal identified the presence of [redacted] [which is equal to [redacted]] in the liver of the bull. A tolerance of 125 ppb has been established for residues of flunixin in the liver tissue of cattle as codified in 21 C.F.R. 556.286. The presence of gentamicin and fIunixin in the edible tissues of this animal causes the food to be adulterated within the meaning of section 402(a)(2)(C)(ii) [21 U.S.C. § 342(a)(2)(C)(ii)] of the Act. ................snip............end
http://www.fda.gov/foi/warning_letters/g5836d.htm
May 4, 2006
CERTIFIED MAIL
RETURN RECEIPT REQUESTED
In reply refer to Warning Letter SEA 06-27
Ed M. Pomeroy
7304 Vista Drive
Ferndale, WA 98248
WARNING LETTER
Dear Mr. Pomeroy:
An investigation at your dairy operation, located at 2343 Willeys Lake Road, Custer, Washington, conducted by a representative of the U.S. Food and Drug Administration (FDA) on October 18, 2005, and December 5, 2005, revealed that you caused the new animal drug, Neomycin 325 (Neomycin Sulfate powder packet), and the medicated feed, "Instant Amplifier Max MT Medicated" milk replacer (containing neomycin), to become adulterated within the meaning of sections 501(a)(5) of the Federal Food, Drug, and Cosmetic Act (the Act) [21 U.S.C. 351(a)(5)] and 501(a)(6) of the Act [21 U.S.C. 351(a)(6)], and unsafe under section 512 of the Act [21 U.S.C 360b]. You can find the Act and its associated regulations on the Internet through links on the FDA's web page at www.fda.gov
Our investigation determined that on August 12, 2005, and August 26, 2005, you delivered calves to[redacted] a livestock collector, who subsequently tagged the animal with back tags #1007 and #0818, respectively, and delivered the calves to [redacted] on the same dates. The calf with back tags #1007 and #0818, identified on USDA Case #05-0652-WA and further identified on USDA-FSIS lab reports #217272 and #217273, respectively, were delivered for slaughter as human food to [redacted] by [redacted], also on August 12, 2005, and August 26, 2005, respectively. USDA analysis of tissue samples collected from the calves identified the presence of neomycin in the kidney at detectable levels in the calf with back tag #1007 tissue, and at 5.41 ppm in the calf with back tag #0818.
A subsequent investigation revealed that you adulterated the drug, Neomycin 325, within the meaning of section 501(a)(5) of the Act [21 U.S.C. 351 (a)(5)] when you used it in a calf to be processed for veal, which is contrary to the warning on the label. Specifically, you administered the drug, Neomycin 325, by adding it to Instant Amplifier Max NT Medicated Dairy Herd & Beef Calf Milk Replacer, the liquid milk replacer supplement that you feed your calves, contrary to the directions set forth in the approved labeling that clearly state that it is not for use in liquid supplements and contrary to the label statement that it is not to be used in calves to be processed for veal.
Because the Act does not permit the extralabel use of drugs in or on medicated feeds, your actions cause the neomycin to be unsafe under Section 512(a) of the Act, 21 U.S.C. § 360b(a), and adulterated within the meaning of Section 501(a)(5) of the Act, 21 U.S.C. § 351(a)(5).
You also caused the adulteration of an animal feed bearing or containing a new animal drug under section 501(a)(6) of the Act [21 U.S .C. 351(a)(6)} when you failed to use the milk replacer in conformance with its approved labeling by feeding it to calves to be processed for veal and by adding the drug neomycin to it.
The above is not intended ..........snip.......end
http://www.fda.gov/foi/warning_letters/g5835d.htm
http://www.accessdata.fda.gov/scripts/wlcfm/subject.cfm?FL=I
http://www.accessdata.fda.gov/scripts/wlcfm/subject.cfm?FL=D
http://www.accessdata.fda.gov/scripts/wlcfm/subject.cfm?FL=E
http://www.cdc.gov/drugresistance/actionplan/index.htm
http://www.cdc.gov/narms/faq_pages/1.htm
http://www.cdc.gov/narms/faq_pages/2.htm
http://www.cdc.gov/narms/faq_pages/3.htm
http://www.cdc.gov/narms/faq_pages/4.htm
http://www.cdc.gov/narms/faq_pages/5.htm
http://www.cdc.gov/narms/faq_pages/6.htm
http://www.cdc.gov/narms/faq_pages/7.htm
http://www.cdc.gov/narms/faq_pages/8.htm
http://www.cdc.gov/narms/faq_pages/9.htm
National Antimicrobial Resistance Monitoring System (NARMS) Frequently Asked Questions (FAQ) About Antibiotic Resistance - How much is used in food-producing animals?
NARMS Home > FAQ Antibiotic Resistance > How much is used in food-producing animals? In the United States, data on the quantity of antibiotics given to food animals is not available to the public or to government agencies. According to the Union of Concerned Scientists (www.ucsusa.org), about 25 million pounds of antibiotics and related drugs are used every year in livestock for nontherapeutic purposes. The Animal Health Institute (www.ahi.org) estimates that 20.2 million pounds of antibiotics were produced for use in farm and companion animals in 2003.
http://www.cdc.gov/narms/faq_pages/10.htm
National Antimicrobial Resistance Monitoring System (NARMS) Frequently Asked Questions (FAQ) About Antibiotic Resistance - Which antibiotics used in food-producing animals are related to antibiotics used in humans?
NARMS Home > FAQ Antibiotic Resistance > Which antibiotics used in food-producing animals are related to antibiotics used in humans? The majority of antibiotics used in food animals belong to classes of antibiotics which are also used to treat human illness; these include tetracyclines, sulfonamides, penicillins, macrolides, fluoroquinolones, cephalosporins, aminoglycosides, chloramphenicols, and streptogramins. Because these classes of antibiotics are similar, then bacteria resistant to antibiotics used in animals will also be resistant to antibiotics used in humans.
Date: June 1, 2005
Content source: National Center for Infectious Diseases
http://www.cdc.gov/narms/faq_pages/11.htm
National Antimicrobial Resistance Monitoring System (NARMS) Frequently Asked Questions (FAQ) About Antibiotic Resistance - How do resistant bacteria spread from animals to humans?
NARMS Home > FAQ Antibiotic Resistance > How do resistant bacteria spread from animals to humans?
Resistant bacteria may be transferred to humans through the food supply or direct contact with animals. For example, Campylobacter lives in the intestines of chickens. People get Campylobacter diarrhea primarily from eating undercooked chicken. In 1989, none of the Campylobacter strains from ill persons that CDC tested were resistant to fluoroquinolone antibiotics. In 1995, the FDA approved the use of fluoroquinolones in poultry. Soon afterwards, doctors found Campylobacter strains from ill persons that were resistant to fluoroquinolone antibiotics.
Date: June 1, 2005
Content source: National Center for Infectious Diseases
http://www.cdc.gov/narms/faq_pages/12.htm
National Antimicrobial Resistance Monitoring System (NARMS) Frequently Asked Questions (FAQ) About Antibiotic Resistance - What is the human health consequence of increasing antibiotic resistance in foodborne bacteria?
NARMS Home > FAQ Antibiotic Resistance > What is the human health consequence of increasing antibiotic resistance in foodborne bacteria? When an ill person is treated with an antibiotic to which the bacteria is resistant, the antibiotic will not help and may even make the illness worse. Also, increasing antibiotic resistance in the bacteria harbored by animals makes it more likely for humans who do get infected to have a resistant strain. The illness may last longer, be more serious, or more expensive to treat.
Date: June 1, 2005
Content source: National Center for Infectious Diseases
http://www.cdc.gov/narms/faq_pages/13.htm
National Antimicrobial Resistance Monitoring System (NARMS) Frequently Asked Questions (FAQ) About Antibiotic Resistance - What can be done to slow antibiotic resistance?
NARMS Home > FAQ Antibiotic Resistance > What can be done to slow antibiotic resistance? Decreasing unnecessary or imprudent antibiotic use will decrease the pressure on organisms which are exposed to them to become resistant. Ongoing efforts in human and veterinary medicine are needed to decrease the misuse and overuse of antibiotics, so that the efficacy of antibiotics is preserved for as long as possible. For example, medical and veterinary professional organizations have issued recommendations to promote appropriate therapeutic use of antibiotics by physicians and veterinarians. A Task Force of 11 government agencies issued a Public Health Action Plan to Combat Antimicrobial Resistance in 2001. The Public Health Action Plan and annual progress reports on implementation of the plan are available at www.cdc.gov/drugresistance.
Additional information concerning food safety issues related to antimicrobial resistance can be found at the FDA's Center for Veterinary Medicine website.
Date: June 1, 2005
Content source: National Center for Infectious Diseases
http://www.cdc.gov/narms/faq_pages/14.htm
GET SMART: Know When Antibiotics Work on the Farm
Educational Activities to Promote Appropriate Use of Antimicrobial Agents in Animals
The Get Smart on the Farm campaign will have five major areas of activity:
1) Distribute current practices and educational materials
2) Fund sites and provide technical assistance to develop, implement, and evaluate local campaigns
3) Support development and testing of veterinary medical curricula for students
4) Fund a national advertising campaign promoting the appropriate use of antibiotics
5) Develop an efficient and accurate means of measuring antimicrobial use in veterinary medicine and agriculture
Appropriate Use of Antimicrobial Agents: Course Materials for Veterinary Students and Veterinary Continuing Education
This interactive web-based program combines aspects of microbiology, pharmacology, infectious disease and public health to promote appropriate use of antimicrobial agents by veterinarians. Working in partnership with human health professionals, food animal producers, animal owners, and the general public, the appropriate use of antimicrobial agents by veterinarians can help to mitigate further development and spread of resistance in human, animal, and zoonotic pathogens and commensal bacteria. The program consists of two parts:
A Background module that provides an introduction to the global, ecological nature of the antimicrobial resistance problem.
Species-specific modules that contain interactive case scenarios aimed at providing practical, clinical applications for the appropriate use guidelines as set forth in the WHO Global Principles for the Containment of Antimicrobial Resistance in Animals Intended for Food.
Specific topics addressed in the program include:
Mechanisms of resistance
Diagnostic tools and tests
Guidelines for empirical treatment
Client education
Alternatives to antibiotics
Resistance in animals secondary to use of antimicrobial agents
Public health risks of use of antimicrobial agents in food animals and in companion animals and the connection to antimicrobial resistant infections in people
State Demonstration Project: Collaborations Between State Public Health and Veterinary Diagnostic Laboratories
To foster collaborations on antimicrobial resistance between state public health laboratories and state agriculture (veterinary diagnostic) laboratories.
To establish local surveillance of antimicrobial resistance among enteric bacteria from humans and animals.
To develop community-based programs on appropriate use of antimicrobials in animals.
CDC is currently supporting a project between Michigan Department of Community Health and the Diagnostic Center for Animal Population Health at Michigan State University.
For more information contact GET SMART: Know When Antibiotics Work on the Farm :
Stacy Holzbauer, DVM MPH
Centers for Disease Control and Prevention
National Antimicrobial Resistance Monitoring System
1600 Clifton Road, MS-D63
Atlanta, GA 30333
Phone: 404-639-3399
Fax: 404-639-3535
Email:
[email protected]
For more information on the overall Get Smart program, please click HERE.
Date: January 30, 2006
Content source: National Center for Infectious Diseases
http://www.cdc.gov/narms/get_smart.htm
TSS