I worked for a big ass outfit on the Colorado-Utah line several years ago (better part of a decade now, actually, yikes!). One of the neighbors used to run a pile of buffalo instead of cows, but they kept ripping out his fences, so he'd end up getting trespassed by the BLM several times a week. He ended up selling the damned things, but his last gather left seven or eight bulls of various ages running loose on the desert.
We had standing permission from him to shoot them if we saw them.
So one day, I'm in a company Cherokee, after having made the long-ass trip to town. I turn onto my road and this damned buffalo bull is standing in the middle of the road looking at me. I jerked my pistol off my hip and piled out of the Jeep.....
Then piled back in when I realized the damned thing was considerably larger than the Jeep! I sat there for twenty minutes waiting for that big SOB to move out of the road, wondering if he was gonna try and take the truck....
I learned a valuable lesson that day. A .45ACP 1911A1 is a popgun when you're standing twenty feet from a mature buffalo bull!