Heck, I-80 is my back door here, well, about 3 miles away, and yes, it is a truckers road.. Around here at least they never stop.. When I used to drive across South Dakota in the middle of the night it was a bit different, not a lot of truck or car traffic on 90 at 3am.... Generally would start picking back up at sunrise, which was generally near the Minn/Wisconsin border... Don't think I could drive like that... After about 12 hours in the car now I am shot.. Of course, we have to stop ever 3 hours or so for the kids to get out and stretch their legs... At least we got to stop at a neat little zoo in Kansas when we drove out to Colorado last year.
Nothing was quite as lonely as the stetch of highway going South towards Denver in Wyoming..... It was snowing lightly, couldn't eve see lights at any ranch sites and might have seen a car every 30 minutes.. Were driiving to Denver so we could fly down to Miami with the dog... Last time I was on a plane, 1997 I think... I hate flying.