QUOTE
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That’s the $64,000 question,” said assistant chief Johansen. “I’m quite confident, based on our knowledge of the disease and how it spreads, that it didn’t just occur spontaneously.”
He cited three possible sources — the release of a diseased animal from a captive-deer facility, the careless disposal of a CWD-infected carcass brought in from another state, or some unknown hunter’s use of doe-in-estrus scent obtained from the urine of a diseased deer.
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holy mad cow, please tell me i am dreaming, that someone is actually paying attention to 'sound science' and not 'junk science'.............
Docket Management
Docket: 02N-0273 - Substances Prohibited From Use in Animal Food or Feed; Animal Proteins Prohibited in Ruminant Feed
Comment Number: EC -10
Accepted - Volume 2
snip...
DEPARTMENT OF HEALTH & HUMAN SERVICES PUBLIC HEALTH SERVICE FOOD AND DRUG ADMINISTRATION April 9, 2001 WARNING LETTER 01-PHI-12 CERTIFIED MAIL RETURN RECEIPT REQUESTED Brian J. Raymond, Owner Sandy Lake Mills 26 Mill Street P.O. Box 117 Sandy Lake, PA 16145 PHILADELPHIA DISTRICT Tel: 215-597-4390 Dear Mr. Raymond: Food and Drug Administration Investigator Gregory E. Beichner conducted an inspection of your animal feed manufacturing operation, located in Sandy Lake, Pennsylvania, on March 23, 2001, and determined that your firm manufactures animal feeds including feeds containing prohibited materials. The inspection found significant deviations from the requirements set forth in Title 21, code of Federal Regulations, part 589.2000 - Animal Proteins Prohibited in Ruminant Feed. The regulation is intended to prevent the establishment and amplification of Bovine Spongiform Encephalopathy (BSE) . Such deviations cause products being manufactured at this facility to be misbranded within the meaning of Section 403(f), of the Federal Food, Drug, and Cosmetic Act (the Act). Our investigation found failure to label your swine feed with the required cautionary statement Do Not Feed to cattle or other Ruminants The FDA suggests that the statement be distinguished by different type-size or color or other means of highlighting the statement so that it is easily noticed by a purchaser. In addition, we note that you are using approximately 140 pounds of cracked corn to flush your mixer used in the manufacture of animal feeds containing prohibited material. This flushed material is fed to wild game including deer, a ruminant animal. Feed material which may potentially contain prohibited material should not be fed to ruminant animals which may become part of the food chain. The above is not intended to be an all-inclusive list of deviations from the regulations. As a manufacturer of materials intended for animal feed use, you are responsible for assuring that your overall operation and the products you manufacture and distribute are in compliance with the law. We have enclosed a copy of FDA's Small Entity Compliance Guide to assist you with complying with the regulation... blah, blah, blah...
http://www.fda.gov/foi/warning_letters/g1115d.pdf
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now, what about those 'deer scents' of 100% urine', and the prion that is found in urine, why not just pass the prion with the urine to other deer... Mrs. Doe Pee Doe in Estrus Model FDE1 Mrs. Doe Pee's Doe in Estrus is made from Estrus urine collected at the peak of the rut, blended with Fresh Doe Urine for an extremely effective buck enticer. Use pre-rut before the does come into heat. Use during full rut when bucks are most active. Use during post-rut when bucks are still actively looking for does. 1 oz. http://www.gamecalls.net/huntingproducts/deerlures.html ELK SCENT/SPRAY BOTTLE * Works anytime of the year * 100 % Cow Elk-in-Heat urine (2oz.) * Economical - mix with water in spray mist bottle * Use wind to your advantage Product Code WP-ESB $9.95 http://www.elkinc.com/Scent.asp prions in urine?
[PDF] A URINE TEST FOR THE IN-VIVO DIAGNOSIS OF PRION DISEASES
http://www.sigov.si/vurs/PDF/diagnoastika-bse-urin.pdf
snip...
http://www.fda.gov/ohrms/dockets/dailys/03/Jan03/012403/8004be07.htl
-------- Original Message --------
Subject: DOCKET-- 03D-0186 -- FDA Issues Draft Guidance on Use of Material From Deer and Elk in Animal Feed; Availability
Date: Fri, 16 May 2003 11:47:37 -0500
From: "Terry S. Singeltary Sr." <
[email protected]>
To:
[email protected]
Greetings FDA,i would kindly like to comment on;Docket 03D-0186FDA Issues Draft Guidance on Use of Material From Deer and Elk in Animal Feed; AvailabilitySeveral factors on this apparent voluntary proposal disturbs me greatly,please allow me to point them out;1. MY first point is the failure of the partial ruminant-to-ruminant feedban of 8/4/97. this partial and voluntary feed ban of some ruminantmaterials being fed back to cattle is terribly flawed. without the_total_ and _mandatory_ ban of all ruminant materials being fedback to ruminants including cattle, sheep, goat, deer, elk and mink,chickens, fish (all farmed animals for human/animal consumption),this half ass measure will fail terribly, as in the past decades... 2. WHAT about sub-clinical TSE in deer and elk? with the recentfindings of deer fawns being infected with CWD, how many couldpossibly be sub-clinically infected. until we have a rapid TSE test toassure us that all deer/elk are free of disease (clinical and sub-clinical),we must ban not only documented CWD infected deer/elk, but healthyones as well. it this is not done, they system will fail...3. WE must ban not only CNS (SRMs specified risk materials),but ALL tissues. recent new and old findings support infectivityin the rump or ass muscle. wether it be low or high, accumulationwill play a crucial role in TSEs.4. THERE are and have been for some time many TSEs in theUSA. TME in mink, Scrapie in Sheep and Goats, and unidentifiedTSE in USA cattle. all this has been proven, but the TSE in USAcattle has been totally ignored for decades. i will document thisdata below in my references.5. UNTIL we ban all ruminant by-products from being fed backto ALL ruminants, until we rapid TSE test (not only deer/elk) butcattle in sufficient numbers to find (1 million rapid TSE test inUSA cattle annually for 5 years), any partial measures such as theones proposed while ignoring sub-clinical TSEs and not rapid TSEtesting cattle, not closing down feed mills that continue to violate theFDA's BSE feed regulation (21 CFR 589.2000) and not makingfreely available those violations, will only continue to spread theseTSE mad cow agents in the USA. I am curious what we willcall a phenotype in a species that is mixed with who knowshow many strains of scrapie, who knows what strain or how manystrains of TSE in USA cattle, and the CWD in deer and elk (notelling how many strains there), but all of this has been renderedfor animal feeds in the USA for decades. it will get interesting oncesomeone starts looking in all species, including humans here in theUSA, but this has yet to happen... 6. IT is paramount that CJD be made reportable in every state(especially ''sporadic'' cjd), and that a CJD Questionnaire mustbe issued to every family of a victim of TSE. only checking deathcertificates will not be sufficient. this has been proven as well(see below HISTORY OF CJD -- CJD QUESTIONNAIRE)7. WE must learn from our past mistakes, not continue to makethe same mistakes... REFERENCES
snip...
http://www.fda.gov/ohrms/dockets/dailys/03/Jun03/060903/060903.htm
Posted by TSS (Member # 1734) on May 07, 2006 11:26 AMMay 07, 2006 11:26 AM: Transmissible Spongiform Encephalopathies Conference AgendaDay One - 27 June 2006 | Day Two - 28 June 200615.00 TSE-safety of human urine-derived pharmaceuticals Human-derived pharmaceuticals originating from urine are now receiving a similar amount of regulatory attention as blood products. The need and the measures taken by Ferring Pharmaceuticals and other companies to ensure the safety of products such as urinary-derived gonadotrophins and urokinase will be described.Dr Peter A McAnulty, Senior Director, Non-Clinical Development, Ferring Pharmaceuticals A/S, Denmark ==========================DEER & ELK URINE, LURES & SCENT CONTROL DEPARTMENTby MRS.DOE PEE'S Main IndexThe Turkey Pro Sez... "Premium, fresh, top-quality, pure 100% undiluted deer lures from Mrs. Doe Pee really work. I won't trust anything else when I'm after big bucks. Sam Collora, owner of the company, proved how well his products work when he bagged this monster buck in 1996.............snip......end........CWDhttp://www.turkeyhuntingsecrets.com/store/store-luresandscentcontroldept.htmDO A GOOGLE SEARCH ON 100% DEER/ELK SCENT AND potential spreading of CWD;http://www.google.com/search?svnum=30&as_scoring=d&hl=en&ie=UTF-8&edition=us&q=100%25+deer+elk+urine&as_drrb=q&as_qdr=d&btnmeta%3Dsearch%3Dsearch=Search+the+WebCoincident Scrapie Infection andNephritis Lead to UrinaryPrion ExcretionHarald Seeger,1* Mathias Heikenwalder,1* Nicolas Zeller,1Jan Kranich,1 Petra Schwarz,1 Ariana Gaspert,2 Burkhardt Seifert,3Gino Miele,1 Adriano Aguzzi1.Prion infectivity is typically restricted to the central nervous and lymphaticsystems of infected hosts, but chronic inflammation can expand the distribution ofprions. We tested whether chronic inflammatory kidney disorders would triggerexcretion of prion infectivity into urine. Urinary proteins from scrapie-infectedmice with lymphocytic nephritis induced scrapie upon inoculation into noninfectedindicatormice. Prionuria was found in presymptomatic scrapie-infected and in sickmice, whereas neither prionuria nor urinary PrPSc was detectable in prion-infectedwild-type or PrPC-overexpressing mice, or in nephritic mice inoculated withnoninfectious brain. Thus, urine may provide a vector for horizontal prion transmission,and inflammation of excretory organs may influence prion spread.snip...How do prions enter the urine? Upon extrarenalreplication, blood-borne prions may beexcreted by a defective filtration apparatus.Alternatively, prions may be produced locallyand excreted during leukocyturia. Althoughprionemia occurs in many paradigms ofperipheral prion pathogenesis (15, 16), thelatter hypothesis appears more likely, becauseprionuria was invariably associated with localprion replication within kidneys.Urine from one CJD patient was reported toelicit prion disease in mice (17, 18), but not inprimates (19). Perhaps unrecognized nephriticconditions may underlie these discrepantobservations. Inflammation-associated prionuriamay also contribute to horizontal transmissionamong sheep, deer, and elk, whose high efficiencyof lateral transmission is not understood.References and Notessnip...end...TSS14 OCTOBER 2005 VOL 310 SCIENCE www.sciencemag.orgtss
Subject: CWD/POTENTIAL SOURCE/URINE/HUNTERS ? (Mrs. Doe Pee Doe in Estrus)Date: Sun, 14 Jul 2002 08:42:51 -0700From: "Terry S. Singeltary Sr." Reply-To: Bovine Spongiform Encephalopathy To:
[email protected] ######## Bovine Spongiform Encephalopathy ######### 1: Hum Reprod 2002 Jul;17(7):1676-80 Bye-bye urinary gonadotrophins?: Is there a risk of prion diseaseafter the administration of urinary-derived gonadotrophins? Balen A. Department of Reproductive Medicine, The General Infirmary, LeedsLS2 9NS, UK. E-mail:
[email protected] Concern has been raised recently about the possibility of prionproteins appearing in the urine of animals and, possibly, humansaffected by prion disease [scrapie, bovine spongiform encephalopathy(BSE) and Creutzfeldt Jakob disease (CJD)]. A debate has started inwhich the suggestion has been made that the purification of human urinefor the provision of gonadotrophins should be discontinued. Thealternative would be to use recombinantly-derived gonadotrophinpreparations. The recombinant products, however, rely upon bovine serumduring the cell culture process and could potentially also be exposed toabnormal prion proteins. It is reassuring that the different types ofgonadotrophin preparations that are currently available are producedwith either urine or bovine serum that is sourced from countries that atthe present time appear to be free of BSE and new variant CJD. We cantherefore be reassured that the gonadotrophins that we usetherapeutically appear to be equally safe. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12093821&dopt=Abstract Greetings List, besides the _animal protein_ in deer/elk feed, and the CWDinfected road-kill that goes to render to be manufacturedinto feed, not to mention the Scrapie infected sheep of thepast, and Lord only knows about the cattle, but what aboutthe 100% deer urine they use to atract deer ? just one example of many below; CWD/POTENTIAL SOURCE/URINE/HUNTERS ? Mrs. Doe Pee Doe in Estrus Model FDE1 Mrs. Doe Pee's Doe in Estrus is made from Estrus urinecollected at the peak of the rut, blended with Fresh Doe Urine for anextremely effective buck enticer. Use pre-rut before the does come intoheat. Use during full rut when bucks are most active. Use duringpost-rut when bucks are still actively looking for does. 1 oz. http://www.gamecalls.net/huntingproducts/deerlures.html ELK SCENT/SPRAY BOTTLE * Works anytime of the year* 100 % Cow Elk-in-Heat urine (2oz.)* Economical - mix with water in spray mist bottle* Use wind to your advantage Product Code WP-ESB $9.95 http://www.elkinc.com/Scent.asp prions in urine? [PDF] A URINE TEST FOR THE IN-VIVO DIAGNOSIS OF PRION DISEASES http://www.sigov.si/vurs/PDF/diagnoastika-bse-urin.pdf TSS ########### http://mailhost.rz.uni-karlsruhe.de/warc/bse-l.html ############
http://www.ngpc.state.ne.us/cgi-bin/ultimatebb.cgiubb=get_topic;f=12;t=000475
http://www.biggamehunt.net/forums/viewtopic.php?t=7603
TSS