From: Brett Wessler
Sent: Wednesday, October 03, 2012 8:52 AM
To:
[email protected]
Subject: BSE article
Hi Terry, I saw you posted an article I wrote for CattleNetwork. As a reader pointed out, the veterinarian approved cattle over the age allowed by the U.S., but there was no sign of BSE found. I cited an article by Global Winnipeg which inaccurately reported the incident. I have updated the article, would you please update your blog?
Thank you,
Brett
Correction: Canadian vet fined after approving cows over age limit
Correction: It was inaccurately reported in a previous version of the story that the cattle approved for export were infected with BSE. The animals were only above the age allowed by the U.S.
A judge in Winnipeg fined a Manitoba veterinarian $80,000 for allowing cattle over the age allowed by the United States to be exported in 2009.
Dr. Fawcett George Taylor inspected cattle exported to the U.S. for three producers between February 2008 and August 2009. Taylor inspected a total of 163 cattle over the age of 30 months who were exporting to the U.S.
Taylor did not purposely approve the cattle for export, but a busy schedule enabled the oversight. He and the three cattle producers were charged in April 2010.
Global Winnipeg reports Taylor has worked at Brydges and Taylor Veterinary Clinic for 29 years.
Taylor apologized and is not allowed to inspect cattle anymore. He has nine months to pay the fine.
END...TSS
From: Terry S. Singeltary Sr.
Sent: Wednesday, October 03, 2012 9:59 AM
To: Brett Wessler
Subject: Re: BSE article
hello bret,
>>> As a reader pointed out, the veterinarian approved cattle over the age allowed by the U.S., but there was no sign of BSE found. I cited an article by Global Winnipeg which inaccurately reported the incident. I have updated the article, would you please update your blog? <<<
no signs of BSE found ???
that's a red herring Bret.
the facts still remain the same, you can't say they were infected with BSE, or were not infected with BSE, can you, since they were never tested.
the facts remain the same, chances are greater, since they were older cattle, cattle that were banned for a purpose, due to higher BSE risk factors, that some of these cattle were subclinical BSE cases.
FDA STATES ;
These high risk cattle materials are the brains and spinal cords from cattle 30 months of age and older. The 2008 rule also prohibits the use of entire carcass of cattle not inspected and passed for human consumption, unless the cattle are less than 30 months of age, or the brains and spinal cords have been removed.
http://www.fda.gov/animalveterinary/guidancecomplianceenforcement/complianceenforcement/bovinespongiformencephalopathy/default.htm
Detection of PrPSc in peripheral tissues of clinically affected cattle after oral challenge with BSE
Martin Franz1, Martin Eiden1, Anne Balkema-Buschmann1, Justin Greenlee2, Hermann M Schaetzl3, Christine Fast1, Juergen Richt4, Jan-Peter Hildebrandt5 and Martin Groschup1,6 + Author Affiliations
1 Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany; 2 National Animal Disease Center, ARS-USDA, Ames, IA, USA; 3 Depts of Veterinary Sciences and Molecular Biology, University of Wyoming, Laramie, WY, USA; 4 Kansas State University, College of Veterinary Medicine, Manhattan, KS, USA; 5 University Greifswald, Germany
E-mail:
[email protected].
Received 6 June 2012. Accepted 20 August 2012.
Abstract
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative prion disease that mainly affects cattle. Transmission of BSE to humans caused a variant form of Creutzfeldt-Jakob disease (vCJD). Following infection the protease-resistant, disease-associated isoform of prion protein (PrPSc) accumulates in the central nervous system and in other tissues. Many countries have defined bovine tissues that may contain prions as specified risk materials (SRMs), which must not enter the human or animal food chains and therefore must be discarded. Ultrasensitive techniques such as the protein misfolding cyclic amplification (PMCA) have been developed to detect PrPSc when present in miniscule amounts that are not readily detected by other diagnostic methods such as immunohistochemistry or western blot. This study was conducted to determine when and where PrPSc can be found by PMCA in cattle orally challenged with BSE. A total of 48 different tissue samples from 4 orally BSE-infected cattle at clinical stages of disease were examined using a standardized PMCA protocol. The protocol used brain homogenate from bovine PrP transgenic mice (Tgbov XV) as substrate and three consecutive rounds of PMCA. Using this protocol PrPSc was found in brain, spinal cord, nerve ganglia, optic nerve, and Peyer's patches. We could confirm the presence of PrPSc in adrenal gland as well as in mesenteric lymph node – a finding, which was recently reported by another group. Interestingly, additional positive results were obtained for the first time in oesophagus, abomasum, rumen, and rectum of clinically affected cattle.
http://vir.sgmjournals.org/content/early/2012/08/16/vir.0.044578-0.abstract
***Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
http://wwwnc.cdc.gov/eid/article/18/1/pdfs/11-1092.pdf
***Infectivity in skeletal muscle of BASE-infected cattle
http://www.neuroprion.org/resources/pdf_docs/conferences/prion2009/prion2009_bookofabstracts.pdf
***feedstuffs- It also suggests a similar cause or source for atypical BSE in these countries.
http://www.neuroprion.org/resources/pdf_docs/conferences/prion2009/prion2009_bookofabstracts.pdf
***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans.
http://www.neuroprion.org/en/np-neuroprion.html
The present study demonstrated successful intraspecies transmission of H-type BSE to cattle and the distribution and immunolabeling patterns of PrPSc in the brain of the H-type BSE-challenged cattle. TSE agent virulence can be minimally defined by oral transmission of different TSE agents (C-type, L-type, and H-type BSE agents) [59]. Oral transmission studies with H-type BSEinfected cattle have been initiated and are underway to provide information regarding the extent of similarity in the immunohistochemical and molecular features before and after transmission.
In addition, the present data will support risk assessments in some peripheral tissues derived from cattle affected with H-type BSE.
http://www.veterinaryresearch.org/content/pdf/1297-9716-42-79.pdf
Friday, May 11, 2012
Experimental H-type bovine spongiform encephalopathy characterized by plaques and glial- and stellate-type prion protein deposits
***support risk assessments in some peripheral tissues derived from cattle affected with H-type BSE
http://transmissiblespongiformencephalopathy.blogspot.com/2012/05/experimental-h-type-bovine-spongiform.html
the trading of cattle, feed, and other products between the USA, Canada, and Mexico, and the potential TSE prion disease there from, was and is incredible, with Mexico not having a clue ;
http://creutzfeldt-jakob-disease.blogspot.com/2012/06/mexico-is-under-or-mis-diagnosing.html
HOWEVER, I will post your correction Bret. ...
kindest regards, terry
layperson...MOM DOD 12-14-97 Heidenhain Variant Creutzfeldt Jakob Disease 'confirmed'. ...TSS
Tuesday, October 2, 2012
Canadian veterinarian fined after approving BSE MAD cows for export to U.S.A.
http://madcowusda.blogspot.com/2012/10/canadian-veterinarian-fined-after.html
Correction:Canadian vet fined after approving cows over age limit
Brett Wessler, Staff Writer | Updated: October 3, 2012
http://www.cattlenetwork.com/cattle-news/latest/Canadian-veterinarian-fined-after-cows-with-BSE-enter-US-172140311.html
my title to blog changed to this ;
Tuesday, October 2, 2012
Canadian veterinarian fined after approving banned BSE high risk cattle for export to U.S.A.
http://madcowusda.blogspot.com/2012/10/canadian-veterinarian-fined-after.html
kind regards,
terry