Good topic cedardell, however I can't understand your concern about carriers. What do you mean by a carrier, and what are you suggesting. If an animal has misfolded prions in it's system and does not develop a full blown TSE problem, I would see that only as a good thing. Possible resistance due to genetics, etc. etc.

Misfolded prions are the key here. Prions are natural and fine. They have a purpose. Misfolded prions are the concern.

Randy Kaiser