I agree with Soapweed.   I'd be almost as lost in his Sandhills as I would be in Texas.  I have been through the Nebraska Sandhills and it is beautiful ranching country.   I have never visited Texas.

Every region has its own unique advantages and disadvantages.   The phrase "Bloom where you are planted" comes to mind.    I would feel boxed in any large city.   I regularly visit a city of 60K population for medical appts and to visit my sister who lives there.   I'm sure glad when I get home from that ratrace.