tamarack
Well-known member
I dont know too much about genetics but can any one explain. My son has one eye that the top half is brown and the bottom is blue, both of us have blue eyeswhat mixed up genes does he have?
tamarack said:I dont know too much about genetics but can any one explain. My son has one eye that the top half is brown and the bottom is blue, both of us have blue eyeswhat mixed up genes does he have?
Mike". "This gene does something good for people. It makes them have more kids."[/quote said:Think about that for a minute.
redrobin said:With who?Mike said:Maybe those blue eyed people were "Linebreeding"? :lol:
Line breeding only works to get rid of unwanted genes. It won't add genes that aren't there. In your article it says that the blue eyed mutation initiated with a single individual. If the mutation started with one person as a genetic recessive, line breeding wouldn't perpetuate the recessive gene.Mike said:redrobin said:With who?Mike said:Maybe those blue eyed people were "Linebreeding"? :lol:
Oh the usual. Brothers & sisters, nieces & nephews, aunts & uncles, an occasional mommy & daddy, same as the Adam & Eve klan. :lol:
Mutations
As DNA passes from one generation to the next, it acquires small changes, known as mutations. The most common is a change to a single base, for example a change from a T to a C. Other possible changes include the loss or addition of one or more bases. The effect of a mutation depends upon the type of changes and their location in the sequence. Just like one single letter can change a word or even a sentence, a mutation can change the instructions in a gene. Most mutations are considered to be neutral, having little to no impact. Serious mutations can actually cause a protein to stop functioning properly.
Mutations in the DNA can be inherited or acquired. When a mutation is inherited from a parent it is present in almost all of the body's cells. Acquired mutations are changes in the DNA that develop throughout a person's life. They arise in the DNA of individual cells, either spontaneously, or in response to environmental factors such as radiation or viruses. Spontaneous mutations are the most common, caused by copying mistakes in the DNA code as cells form and divide. Most of the time the cell recognizes the mistake and repairs it, but sometimes it passes the mutation on as it divides and creates new cells.
DNA doesn't have long-term memory, so any mutations which develop in a gene are reproduced and passed down to future generations. By comparing the mutations of two individuals, it is possible to calculate how closely they're related. By calculating the mutation rate, researchers can deduce how far back in time different groups split apart.
New Genes Involved in Human Eye Color Identified
May 7, 2010 — Three new genetic loci have been identified with involvement in subtle and quantitative variation of human eye color.
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The study, led by Manfred Kayser of the Erasmus University Medical Center Rotterdam, The Netherlands, is published May 6 in the open-access journal PLoS Genetics.
Previous studies on the genetics of human eye color used broadly-categorized trait information such as 'blue', 'green', and 'brown'; however, variation in eye color exists in a continuous grading from the lightest blue to the darkest brown.
In this genome-wide association study, the eye color of about 6000 Dutch Europeans from the Rotterdam Study was digitally quantified using high-resolution full-eye photographs. This quantitative approach, which is cost-effective, portable, and time efficient, revealed that human eye color varies along more dimensions than are represented by the color categories used previously.
The researchers identified three new loci significantly associated with quantitative eye color. One of these, the LYST gene, was previously considered a pigmentation gene in mice and cattle, whereas the other two had no previous association with pigmentation.
These three genes, together with previously identified ones, explained over 50% of eye color variance, representing the highest accuracy achieved so far in genomic prediction of complex and quantitative human traits.
5 hrs ago the DR's and the Professors couldn't be wrong, now we have late breaking discovery that they didn't know all the facts. Sheesh. :lol:Mike said:OK. So I guess all these Dr's & Professors are nuts and have come up with some sort of diabolical plan?
The research study has been out for a while with plenty of time for their peers (Geneticists, Biologists & the like) to review & debunk it. Maybe you'd like to give it a shot? :lol: :lol:
Mutations
As DNA passes from one generation to the next, it acquires small changes, known as mutations. The most common is a change to a single base, for example a change from a T to a C. Other possible changes include the loss or addition of one or more bases. The effect of a mutation depends upon the type of changes and their location in the sequence. Just like one single letter can change a word or even a sentence, a mutation can change the instructions in a gene. Most mutations are considered to be neutral, having little to no impact. Serious mutations can actually cause a protein to stop functioning properly.
Mutations in the DNA can be inherited or acquired. When a mutation is inherited from a parent it is present in almost all of the body's cells. Acquired mutations are changes in the DNA that develop throughout a person's life. They arise in the DNA of individual cells, either spontaneously, or in response to environmental factors such as radiation or viruses. Spontaneous mutations are the most common, caused by copying mistakes in the DNA code as cells form and divide. Most of the time the cell recognizes the mistake and repairs it, but sometimes it passes the mutation on as it divides and creates new cells.
DNA doesn't have long-term memory, so any mutations which develop in a gene are reproduced and passed down to future generations. By comparing the mutations of two individuals, it is possible to calculate how closely they're related. By calculating the mutation rate, researchers can deduce how far back in time different groups split apart.New Genes Involved in Human Eye Color Identified
May 7, 2010 — Three new genetic loci have been identified with involvement in subtle and quantitative variation of human eye color.
Share This:
200
The study, led by Manfred Kayser of the Erasmus University Medical Center Rotterdam, The Netherlands, is published May 6 in the open-access journal PLoS Genetics.
Previous studies on the genetics of human eye color used broadly-categorized trait information such as 'blue', 'green', and 'brown'; however, variation in eye color exists in a continuous grading from the lightest blue to the darkest brown.
In this genome-wide association study, the eye color of about 6000 Dutch Europeans from the Rotterdam Study was digitally quantified using high-resolution full-eye photographs. This quantitative approach, which is cost-effective, portable, and time efficient, revealed that human eye color varies along more dimensions than are represented by the color categories used previously.
The researchers identified three new loci significantly associated with quantitative eye color. One of these, the LYST gene, was previously considered a pigmentation gene in mice and cattle, whereas the other two had no previous association with pigmentation.
These three genes, together with previously identified ones, explained over 50% of eye color variance, representing the highest accuracy achieved so far in genomic prediction of complex and quantitative human traits.
Turns out that Eye Color inheritance is not so cut & dry:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000934
Time will tell Mike.Mike said:The latter paper was from a few years ago. Before the other. As far as I can see, there are no antagonisms between the two.
Maybe it's not them that don't know genetics? :wink:
Science is always settled. That doesn't mean it's right. :lol:Whitewing said:The science is settled.![]()