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[Docket No. 03-025IFA] SRMs and downer cattle

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Sep 3, 2005
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[Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and Requirement for the Disposition of Non-Ambulatory Disabled Cattle

Terry S. Singeltary

Page 1 of 17

From: Terry S. Singeltary Sr. [[email protected]]

Sent: Thursday, September 08, 2005 6:17 PM

To: [email protected]

Subject: [Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and Requirements

for the Disposition of Non-Ambulatory Disabled Cattle

Greetings FSIS,

I would kindly like to submit the following to [Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and

Requirements for the Disposition of Non-Ambulatory Disabled Cattle

THE BSE/TSE SUB CLINICAL Non-Ambulatory Disabled Cattle

Broken bones and such may be the first signs of a sub clinical BSE/TSE Non-Ambulatory Disabled Cattle ;



Issued: Monday, 28 August 2000



A team of researchers led by Professor John Collinge at the Medical

Research Council Prion Unit1 report today in the Proceedings of the

National Academy of Sciences, on new evidence for the existence of a

?sub-clinical? form of BSE in mice which was unknown until now.

The scientists took a closer look at what is known as the ?species

barrier? - the main protective factor which limits the ability of

prions2 to jump from one species to infect another. They found the mice

had a ?sub-clinical? form of disease where they carried high levels of

infectivity but did not develop the clinical disease during their normal

lifespan. The idea that individuals can carry a disease and show no

clinical symptoms is not new. It is commonly seen in conventional

infectious diseases.

Researchers tried to infect laboratory mice with hamster prions3 called

Sc237 and found that the mice showed no apparent signs of disease.

However, on closer inspection they found that the mice had high levels

of mouse prions in their brains. This was surprising because it has

always been assumed that hamster prions could not cause the disease in

mice, even when injected directly into the brain.

In addition the researchers showed that this new sub-clinical infection

could be easily passed on when injected into healthy mice and hamsters.

The height of the species barrier varies widely between different

combinations of animals and also varies with the type or strain of

prions. While some barriers are quite small (for instance BSE easily

infects mice), other combinations of strain and species show a seemingly

impenetrable barrier. Traditionally, the particular barrier studied here

was assumed to be robust.

Professor John Collinge said: "These results have a number of important

implications. They suggest that we should re-think how we measure

species barriers in the laboratory, and that we should not assume that

just because one species appears resistant to a strain of prions they

have been exposed to, that they do not silently carry the infection.



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snip...FULL TEXT;

THE infamous USA SPORADIC CJDs, something to ponder;

IF the USA TSE in cattle all does not look like UK BSE, why would all USA human TSE look like UK nvCJD???

over 20 strains of scrapie documented to date with new atypical strains now being documented in sheep and goat i.e. BSE.

atypical strains of BSE/TSE showing up in cattle in different countries?

ALL animals for human/animal consumption must be tested for TSE.

ALL human TSEs must be made reportable Nationally and Internationally, OF ALL AGES...

IN a time when FSIS/APHIS/USDA/FDA et al should be strengthening the TSE regulations, it seems corporate interest has won out again over sound science and consumer

protection from an agent that is 100% fatal for the ones that go clinical. With the many different atypical TSEs showing up in different parts of the world, and with GWs BSE

MRR policy (the legal policy of trading all strains of TSEs), the battle that has waged for the last 25 years to eradicate this agent from this planet will be set back decades, if

not lost for good. ...

Terry S. Singeltary Sr.

P.O. Box 42

Bacliff, Texas USA 77518




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