Unusual Calf Report
February 11, 2009
Dr. Jonathan Beever of the University of Illinois has made us aware of a potential separate lethal genetic defect that may involve similar lines of cattle as those associated with Arthrogryposis Multiplex (AM). These calves display a hydrocephalus phenotype more commonly described as water on the brain. It's likely that some of these calves have previously been confused with AM calves.
We recently had the first calf of this type reported to ABS. The calf was thought to be sired by 29AN1608 Dr J ANALYST M250 and was reported to Dr. Beever for investigation. In an abundance of caution we temporarily suspended sales on ANALYST until more was understood about this condition and the calf that has been reported.
ABS routinely investigates any abnormal calves reported to us that appear to be genetic in nature utilizing resources like Dr. David Steffen at the University of Nebraska, Dr. Beever and the respective breed association.
Our policy has been and continues to be to label any bull that has been determined to be a carrier of a deleterious gene through either approved DNA testing or the identification of two or more calves that have been parent verified and confirmed through pathology to be affected by a known genetic defect.
Today, we received parent verification that the calf submitted was in fact sired by ANALYST. While this condition and its inheritance are not fully understood, Dr. Beever and Dr. Steffen have also received other affected calves with similar extended pedigrees and from a wide geographic area indicating a possible genetic component.
When more is known about this condition and suspect pedigrees, ABS will communicate that information to our Representatives and customers. We encourage you to report any unusual calves to ABS, the respective breed association and to Drs. Beever or Steffen. They will assist and coordinate getting samples distributed appropriately for complete investigation.
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