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Ridley Agrees to Settlement in Canadian BSE Lawsuit

  • Thread starter Thread starter Anonymous
  • Start date Start date
A range of between 4 and 23 in the entire herd? In the USDA's OTM proposal, they estimated that they would be importing between 19 and 105 cases of BSE from Canada. Now, if you've only got 23 TOTAL, how can we find 105 in just the ones we are importing?
 
Apparently the way you do that is to take the worst case scenario and add up what might happen over the next twenty years in total (19 infected imports over 20 years or approximately one per year), then you take that number and multiply it again by discounting the new UK feed ban risk data to get the absolute inflated worst case scenario of 108 infected animals over the next 20 years (approximately 5 per year).

To quote from page 70 of the revised USDA assessment of risk from Rule 2:

"Even though APHIS concludes that decreasing Canadian prevalence is most likely, we
quantitatively analyze the impact of the constant BSE prevalence produced by the BBC
model to simulate potential BSE exposure in U.S. cattle. This calculation provides a
reasonable estimate (and likely an overestimate) of prevalence and subsequent release of
infectivity over the 20 years of the analysis. Using the BBC estimate over this
timeframe, the model estimates release of approximately 19 infected bovines. As an
expression of our uncertainty regarding the application to Canada's prevalence
calculation of the additional UK data on the efficacy of a feed ban, we performed a
sensitivity analysis which excluded this additional information. That more risk-inflating
and less likely scenario results in the importation 108 infected bovines over 20 years."

Based on the USDA Rule 2 worst case scenario analysis imports from Canada may cause BSE in 2 US cattle over the next 20 years (page 71):

"This model indicates that even when assuming no drop in prevalence in
imported Canadian cattle and overestimating the potential for BSE to pass various steps
in the exposure pathway, there is little spread of disease to U.S. animals. When including
these assumptions, the release of approximately 19 imported infected animals, leads to
approximately two U.S. cases as secondary spread and 0.67 animals showing clinical
signs over the 20 years of the analysis."

http://www.aphis.usda.gov/newsroom/hot_issues/bse/downloads/RiskAssessment06-041-1%20.pdf

The USDA says that in the worst case scenario Canadian imports might cause 1 case of clinical BSE in the US (page 71) in the next 30 years. Of course this figure is based on the upgraded Canadian feed ban having no effect on prevalence of BSE in Canada.

Somehow I just can't get too exited about the potential risk (which the USDA says is inflated) of one case of BSE in 30 years in the US herd as a result of Canadian live cattle imports.
 
Shaft said:
You boys need to be focussing your energy and venom on Argentina and Brazil. They are the real threat.

If Argentina and Brazil are the "real threat", why aren't Canada and Australia?

I tend to agree with you on the low risk of BSE, but there is one phrase that will keep this issue from going away..."always fatal"! "Sound science" is not the most important factor in selling beef, consumer perception is!!!

And as for the "sound science" you are relying on with this study...

At one time "sound science" said margarine was more healthful than butter....until "new sound science" found that trans-fats(40-50% of margarine) causes cancer and heart problems!

Genetic "sound science" knew that when the human genome was mapped, there would be over 100,000 genes. Turns out, we only have a couple thousand more than the average earthworm!

I think you get my point.

Welcome to the forum!!!
 
Shaft, "Apparently the way you do that is to take the worst case scenario and add up what might happen over the next twenty years in total (19 infected imports over 20 years or approximately one per year), then you take that number and multiply it again by discounting the new UK feed ban risk data to get the absolute inflated worst case scenario of 108 infected animals over the next 20 years (approximately 5 per year). "

There's still huge red flags here. You've said Canada's "worst case scenario" is one case for every 625,000, and you've got a herd size of 15MM. That gives you 24 cases on the ground today - TOTAL. Yet, the USDA admits they could IMPORT 106 (and considering how they've bent over backwards and even blatantly lied to get the border open, I wouldn't bet a nickel againt them holding down that figure). We're importing more than 5 times what you have in the total population! That means that either that 24 number is way too low, or that BSE will continue to spread up there - which again contradicts one of their foundation arguements on the OTM rule which was that Canada has an effective feed ban.
 
Shaft good to see someone new. SH is fixated on canada. The R-CALF leadership tells SH what to think and he follows the leader not questioning the all knowing leader. If he can stop the evil empire :roll: of Canada from exporting beef to the US his life has been worth while :P . Just wait a while he will eventually make the personal attacks and contradict himself. You will see he is right and you are wrong even when he agrees with you.
 
QUESTION said:
Shaft good to see someone new. SH is fixated on canada. The R-CALF leadership tells SH what to think and he follows the leader not questioning the all knowing leader. If he can stop the evil empire :roll: of Canada from exporting beef to the US his life has been worth while :P . Just wait a while he will eventually make the personal attacks and contradict himself. You will see he is right and you are wrong even when he agrees with you.

I'm not fixated on Canada. If I have a fixation, it's the USDA doing the job they were assigned to by Congress; To keep our food safe and our herd healthy.

However, Shaft, it is good to have somebody new that brings thought-out, clear arguements to the table. Welcome.
 
Sandhusker,

The USDA number of 108 maximum BSE positive imports is a twenty-year total. Twenty years. That number was reached by multiplying the admittedly bulked up maximum twenty year total of BSE positives of 19 to discount the latest information from the UK that was included in calculating the twenty year total of 19. Twenty year total. Twenty. Years. Total. That works out to a rabid maximum of 5 per year, or a less rabid maximum of 1 per year.

Take 24 total positives and subtract 5 or 1 per year, depending upon how extreme your viewpoint is, and there is no problem with the math.

RobertMac,

"Sound science" is not the most important factor in selling beef, consumer perception is!!!

I couldn't agree more. That is why the cold hard numbers need to be presented, if at all, in a clear rational way to the public. There simply is no genuine public health threat posed by BSE in North America. As the old saying goes, 'friendly fire isn't'. Canadian and American producers need to be working together to ease public fears and expand markets. Until NAFTA goes away (and that isn't about to happen any time soon) we are stuck with one another. Best to make the most of it in my humble opinion. Something about that old "e pluribus unum" idea that appeals to my tender sensibilities.

As for Argentina and Brazil, when I see those kind, caring and producer-friendly folks at Tyson and Cargill pouring hundreds of millions of dollars into South America, it makes me nervous. Maybe I'm just being paranoid.
 
Shaft, "The USDA number of 108 maximum BSE positive imports is a twenty-year total. Twenty years"

I understand that. However, assuming that they are correct that Canada has at most 24 positives in the entire herd today, that means that BSE is spreading, otherwise how can 24 grow to 108? Also, don't lose sight that they are talking 24 TOTAL today and 106 as just the portion that we are importing. If BSE is spreading, that means the feed ban is not working which shoots their reasoning for opening the border out of the saddle.

You can take USDA's own words and figures and turn it against them. They are the best witnesses for their own prosecution! That's the way this whole thing has been from the start.
 
Sandhusker,

My take on the 24 number is a little different. Cattle die, cattle are born. If you look at the national herd sizes of Canada and the US they don't change that much from year to year. The effects of procreation and slaughter tend to cancel each other out. Same with BSE. Some existing cases go to the abbatoir, some calves get infected. The total number of positives remains relatively constant. Stable state dynamics.

If BSE could be spread by cattle sneezing on each other in the subway, that would be another matter entirely. However, all the hard evidence to date indicates that the only means of transmission is through the feeding of infected feed to calves. No pandemic possibilities without lots and lots of tainted calf starter.

There is no evidence that the number of cases in either Canada or the US is growing. On the contrary, the British experience indicates that the number of cases must be decreasing, particularly in Canada due to the July 2007 'enhanced' feed ban.

The Canadian government finally did what the Brits did to upgrade their feed ban back in 1990 and 1996 to address the problems of 'cross-feeding' and 'cross-contamination' respectively.

Cross-feeding is when you run out of calf starter and are just too darn busy to go to town to pick up some more just then, so you add a little pig or chicken feed containing RMBM to the calves' feed mix to tide them over for the moment until you get the chance to make that run into town. Oops.

Cross-contamination is when the feed mill makes or transports pig or chicken feed containing RMBM and then follows that up with calf starter on the same production line or truck. Prions are pesky and don't clean, disinfect or inactivate too easily and a little bit goes a long way. The Brits started to recognize cross-contamination as a major problem back in 1994 and finally got around to tightening up their feed ban to deal with it in March 1996 by eliminating RMBM from all animal feed, period. Canada was a little slow off the mark in that respect and the US hasn't gotten there yet.

The bottom line as I see it is that the numbers just don't justify the panic. The real problem, as RobertMac has correctly identified it, is that Andre Agassi was right when he said 'image is everything'. If people everywhere didn't fundamentally prefer their own opinions to the truth then what would be the point of that famous old saying; 'don't confuse me with the facts, I've already made up my mind'?

BSE is a PR and marketing problem. Not a genuine animal health problem and certainly not a public health problem. Say it with me now. Loud and proud.

The truth is the best way to access and maintain markets of all shapes and sizes in my experience.
 
If you have stable state dynamics, you have a failure of the feed ban, as the feed ban was implemented to stop the expansion and creation of new cases. They're supposed to be dying off and not getting replaced.
 
Shaft said:
......SNIP

If BSE could be spread by cattle sneezing on each other in the subway, that would be another matter entirely. However, all the hard evidence to date indicates that the only means of transmission is through the feeding of infected feed to calves. No pandemic possibilities without lots and lots of tainted calf starter.

There is no evidence that the number of cases in either Canada or the US is growing. On the contrary, the British experience indicates that the number of cases must be decreasing, particularly in Canada due to the July 2007 'enhanced' feed ban.

The Canadian government finally did what the Brits did to upgrade their feed ban back in 1990 and 1996 to address the problems of 'cross-feeding' and 'cross-contamination' respectively.

Cross-feeding is when you run out of calf starter and are just too darn busy to go to town to pick up some more just then, so you add a little pig or chicken feed containing RMBM to the calves' feed mix to tide them over for the moment until you get the chance to make that run into town. Oops.

Cross-contamination is when the feed mill makes or transports pig or chicken feed containing RMBM and then follows that up with calf starter on the same production line or truck. Prions are pesky and don't clean, disinfect or inactivate too easily and a little bit goes a long way. The Brits started to recognize cross-contamination as a major problem back in 1994 and finally got around to tightening up their feed ban to deal with it in March 1996 by eliminating RMBM from all animal feed, period. Canada was a little slow off the mark in that respect and the US hasn't gotten there yet.

The bottom line as I see it is that the numbers just don't justify the panic. The real problem, as RobertMac has correctly identified it, is that Andre Agassi was right when he said 'image is everything'. If people everywhere didn't fundamentally prefer their own opinions to the truth then what would be the point of that famous old saying; 'don't confuse me with the facts, I've already made up my mind'?

BSE is a PR and marketing problem. Not a genuine animal health problem and certainly not a public health problem. Say it with me now. Loud and proud.

The truth is the best way to access and maintain markets of all shapes and sizes in my experience.


HERE are the facts your are missing there shaft, and these facts speak for themselves........



Certain Aspects related to the Feeding of Animal Proteins to Farm
Animals[1] - Scientific Opinion of the Panel on Biological Hazards
Question number: EFSA-Q-2007-084


Adopted date: 17/10/2007
Summary

Opinion

Summary

The European Food Safety Authority (EFSA) was requested by the European
Parliament (EP) to assess, with respect to Bovine Spongiform Encephalopathy
(BSE), the safety for human health of the utilisation of non-ruminant Meat
and Bone Meal (MBM). More specifically, EFSA was requested (i) to evaluate
the risk from using non-ruminant MBM in pig and poultry feed, once it is
possible to distinguish protein origin up to different species and (ii) the
introduction of certain tolerance levels with regard to small quantities of
MBM in animal feed and the parameters which could be utilized to define
these tolerance levels and quantities.

The EFSA opinion takes account of the general control measures in place in
the European Union (EU) and assumes the effectiveness of these controls in
avoiding cross-contamination, both deliberate and accidental. This opinion
considers all available scientific data and information related to the risk
of transmission of the BSE agent through feed and, by this means, addresses
the risk of causing BSE related exposure to humans, as well as risks related
to some other TSE agents. In replying to the above mentioned questions, this
assessment only considers the use of pig Processed Animal Proteins[2] (PAPs)
in poultry feed and the use of poultry PAPs in pig feed. With respect to the
introduction of certain tolerance levels with regards to small quantities of
MBM in animal feed, this assessment considers such a tolerance for animal
proteins of any species in animal feed.

To date, no Transmissible Spongiform Encephalopathies (TSEs) have been
identified as occurring in pigs or poultry under natural conditions. Taking
account of the epidemiological situation of BSE in cattle in the EU, which
indicates a decreasing trend, together with the current control measures in
place to avoid exposure of pigs and poultry to BSE contaminated material,
the EFSA Scientific Panel on Biological Hazards (BIOHAZ) concluded that the
risk of transmitting BSE to pigs utilizing poultry PAPs and vice versa is
negligible. Consequently in this scenario any increase in the exposure risk
of BSE to humans would be negligible. If TSE in birds or pigs is identified
in the future as occurring under natural conditions, the assessment
presented here will no longer be valid.

The BIOHAZ Panel further concluded that the risk of transmitting BSE through
small quantities of animal proteins in feed to ruminants can not be
excluded, but considering the current protective measures in place in the
EU[3], the few infected animals that could arise from this contamination
would probably not be able to sustain the BSE epidemic but would increase
the human exposure risk to BSE. The risk of transmitting BSE to
non-ruminants is considered to be lower than to ruminants, as long as
intra-species recycling is avoided. Consequently in this scenario the
increase in the exposure risk of BSE to humans is negligible.

In the event that a tolerance level was required to be set up in order to
quantify animal proteins in animal feed, the BIOHAZ Panel considered the
Limit of Quantification (LOQ) of the method used to set such tolerance level
as the parameter required. However the BIOHAZ Panel concluded that it is
currently not possible to set a LOQ because of insufficient data on the
performance of relevant detection methods for quantification. It is
therefore recommended that studies be conducted to define the LOQ for
different types of animal proteins in feed.
In a hypothetical situation in which pigs are allowed to be fed with poultry
PAPs and vice versa or, in general, inter-species recycling is allowed,
currently it is not possible to quantify the level of contamination with non
authorized products containing animal proteins in feed. Accordingly it is
technically not possible at present to determine whether the contamination
is below or above a defined tolerance level.

The BIOHAZ Panel further concluded that compared to the current measures in
place in EU, the introduction of a tolerance level, which has to be defined
at a certain level above the LOQ, will lead to an increase in the risk of
transmission of BSE or other TSEs, depending on the species. This increased
risk can not be quantified.
___________________________
[1] For citation purposes: Opinion of the Scientific Panel on Biological
Hazards on a request from the European Parliament on Certain Aspects related
to the Feeding of Animal Proteins to Farm Animals, The EFSA Journal (2007)
Journal number 576, 1-41
[2] In Commission Regulation (EC) No 829/2007 of 28 June 2007 is defined as:
"animal protein derived entirely from Category 3 material, which have been
treated in accordance with Chapter II of Annex VII so as to render them
suitable for direct use as feed material or for any other use in
feedingstuffs, including petfood, or for use in organic fertilisers or soil
improvers; however, it does not include blood products, milk, milk-based
products, colostrum, gelatine, hydrolysed proteins and dicalcium phosphate,
eggs and egg-products, tricalcium phosphate and collagen".
[3] Regulation (EC) 999/2001 as amended and Regulation (EC) 1774/2002 as
amended.




Publication date: 15/11/2007


http://www.efsa.europa.eu/EFSA/Scientific_Opinion/biohaz_op_ej576_animal_proteins_summary_en.pdf

http://www.efsa.europa.eu/EFSA/Scientific_Opinion/biohaz_op_ej576_animal_proteins_en.pdf




If only a proportion of infected cattle can be detected, does testing provide significant
consumer protection?

The extent to which testing increases consumer protection is still open to question,
especially if other protective measures are in place (see below).
It is conceivable that tissues not previously recognised as infected may still be found
as research continues. Infectivity levels are expected to be extremely low, and
undetectable with the tools used so far. If these tissues were otherwise consumed then
the destruction of the carcase would afford the consumer a greater degree of
protection. If the tissues are not sufficiently infectious to pose a health risk, and/or are
not consumed, then the additional protection provided may be nil.
Recent results from Japan and Germany confirm this point(2,11,12,14), with positivity or
infectivity being detected in some peripheral nerves that would not normally be
removed as SRM. The amount of infectivity present is low, and considered be up to
1000-fold lower than the brain. Unpublished evidence suggests that these become
positive only after the brain and spinal cord. This therefore confirms that testing and
removal of positive animals does provide some additional, as yet unquantifiable,
protection to consumers over and above that provided by removal of SRM. Given that
detection of positivity or infectivity in some peripheral nerves coincides with the onset
of clinical signs, it is probable that such animals would be detected before slaughter,
and therefore excluded from the food chain.

http://www.tafsforum.org/position_papers/TAFS_POSITION_PAPER_ON_TESTING_OF_CATTLE_FOR_BSE_070516.pdf




10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA 2007



Date: March 21, 2007 at 2:27 pm PST
RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II
___________________________________
PRODUCT
Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried, Recall # V-024-2007
CODE
Cattle feed delivered between 01/12/2007 and 01/26/2007
RECALLING FIRM/MANUFACTURER
Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007. Firm initiated recall is ongoing.
REASON
Blood meal used to make cattle feed was recalled because it was cross-contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement.
VOLUME OF PRODUCT IN COMMERCE
42,090 lbs.
DISTRIBUTION
WI

___________________________________
PRODUCT
Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A-BYPASS ML W/SMARTA, Recall # V-025-2007
CODE
The firm does not utilize a code - only shipping documentation with commodity and weights identified.
RECALLING FIRM/MANUFACTURER
Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete.
REASON
Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement.
VOLUME OF PRODUCT IN COMMERCE
9,997,976 lbs.
DISTRIBUTION
ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007


http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html


Subject: MAD COW FEED RECALL USA SEPT 6, 2006 1961.72 TONS IN COMMERCE AL,
TN, AND WV
Date: September 6, 2006 at 7:58 am PST

PRODUCT
a) EVSRC Custom dairy feed, Recall # V-130-6;
b) Performance Chick Starter, Recall # V-131-6;
c) Performance Quail Grower, Recall # V-132-6;
d) Performance Pheasant Finisher, Recall # V-133-6.
CODE
None
RECALLING FIRM/MANUFACTURER
Donaldson & Hasenbein/dba J&R Feed Service, Inc., Cullman, AL, by telephone
on June 23, 2006 and by letter dated July 19, 2006. Firm initiated recall is
complete.
REASON
Dairy and poultry feeds were possibly contaminated with ruminant based
protein.
VOLUME OF PRODUCT IN COMMERCE
477.72 tons
DISTRIBUTION
AL
______________________________
PRODUCT
a) Dairy feed, custom, Recall # V-134-6;
b) Custom Dairy Feed with Monensin, Recall # V-135-6.
CODE
None. Bulk product
RECALLING FIRM/MANUFACTURER
Recalling Firm: Burkmann Feed, Greeneville, TN, by Telephone beginning on
June 28, 2006.
Manufacturer: H. J. Baker & Bro., Inc., Albertville, AL. Firm initiated
recall is complete.
REASON
Possible contamination of dairy feeds with ruminant derived meat and bone
meal.
VOLUME OF PRODUCT IN COMMERCE
1,484 tons
DISTRIBUTION
TN and WV


http://www.fda.gov/bbs/topics/enforce/2006/ENF00968.html



Subject: MAD COW FEED RECALLS ENFORCEMENT REPORT FOR AUGUST 9, 2006 KY, LA,
MS, AL, GA, AND TN 11,000+ TONS
Date: August 16, 2006 at 9:19 am PST

RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINE - CLASS II
______________________________
PRODUCT
Bulk custom made dairy feed, Recall # V-115-6
CODE
None
RECALLING FIRM/MANUFACTURER
Hiseville Feed & Seed Co., Hiseville, KY, by telephone and letter on or
about July 14, 2006. FDA initiated recall is ongoing.
REASON
Custom made feeds contain ingredient called Pro-Lak which may contain
ruminant derived meat and bone meal.
VOLUME OF PRODUCT IN COMMERCE
Approximately 2,223 tons
DISTRIBUTION
KY

______________________________
PRODUCT
Bulk custom made dairy feed, Recall # V-116-6
CODE
None
RECALLING FIRM/MANUFACTURER
Rips Farm Center, Tollesboro, KY, by telephone and letter on July 14, 2006.
FDA initiated recall is ongoing.
REASON
Custom made feeds contain ingredient called Pro-Lak which may contain
ruminant derived meat and bone meal.
VOLUME OF PRODUCT IN COMMERCE
1,220 tons
DISTRIBUTION
KY

______________________________
PRODUCT
Bulk custom made dairy feed, Recall # V-117-6
CODE
None
RECALLING FIRM/MANUFACTURER
Kentwood Co-op, Kentwood, LA, by telephone on June 27, 2006. FDA initiated
recall is completed.
REASON
Possible contamination of animal feed ingredients, including ingredients
that are used in feed for dairy animals, with ruminant derived meat and bone
meal.
VOLUME OF PRODUCT IN COMMERCE
40 tons
DISTRIBUTION
LA and MS

______________________________
PRODUCT
Bulk Dairy Feed, Recall V-118-6
CODE
None
RECALLING FIRM/MANUFACTURER
Cal Maine Foods, Inc., Edwards, MS, by telephone on June 26, 2006. FDA
initiated recall is complete.
REASON
Possible contamination of animal feed ingredients, including ingredients
that are used in feed for dairy animals, with ruminant derived meat and bone
meal.
VOLUME OF PRODUCT IN COMMERCE
7,150 tons
DISTRIBUTION
MS

______________________________
PRODUCT
Bulk custom dairy pre-mixes, Recall # V-119-6
CODE
None
RECALLING FIRM/MANUFACTURER
Walthall County Co-op, Tylertown, MS, by telephone on June 26, 2006. Firm
initiated recall is complete.
REASON
Possible contamination of dairy animal feeds with ruminant derived meat and
bone meal.
VOLUME OF PRODUCT IN COMMERCE
87 tons
DISTRIBUTION
MS

______________________________
PRODUCT
Bulk custom dairy pre-mixes, Recall # V-120-6
CODE
None
RECALLING FIRM/MANUFACTURER
Ware Milling Inc., Houston, MS, by telephone on June 23, 2006. Firm
initiated recall is complete.
REASON
Possible contamination of dairy animal feeds with ruminant derived meat and
bone meal.
VOLUME OF PRODUCT IN COMMERCE
350 tons
DISTRIBUTION
AL and MS

______________________________
PRODUCT
a) Tucker Milling, LLC Tm 32% Sinking Fish Grower, #2680-Pellet,
50 lb. bags, Recall # V-121-6;
b) Tucker Milling, LLC #31120, Game Bird Breeder Pellet,
50 lb. bags, Recall # V-122-6;
c) Tucker Milling, LLC #31232 Game Bird Grower,
50 lb. bags, Recall # V-123-6;
d) Tucker Milling, LLC 31227-Crumble, Game Bird Starter, BMD
Medicated, 50 lb bags, Recall # V-124-6;
e) Tucker Milling, LLC #31120, Game Bird Breeder, 50 lb bags,
Recall # V-125-6;
f) Tucker Milling, LLC #30230, 30 % Turkey Starter, 50 lb bags,
Recall # V-126-6;
g) Tucker Milling, LLC #30116, TM Broiler Finisher,
50 lb bags, Recall # V-127-6
CODE
All products manufactured from 02/01/2005 until 06/20/2006
RECALLING FIRM/MANUFACTURER
Recalling Firm: Tucker Milling LLC, Guntersville, AL, by telephone and visit
on June 20, 2006, and by letter on June 23, 2006.
Manufacturer: H. J. Baker and Brothers Inc., Stamford, CT. Firm initiated
recall is ongoing.
REASON
Poultry and fish feeds which were possibly contaminated with ruminant based
protein were not labeled as "Do not feed to ruminants".
VOLUME OF PRODUCT IN COMMERCE
7,541-50 lb bags
DISTRIBUTION
AL, GA, MS, and TN

END OF ENFORCEMENT REPORT FOR AUGUST 9, 2006

###


http://www.fda.gov/bbs/topics/ENFORCE/2006/ENF00964.html


Subject: MAD COW FEED RECALL MI MAMMALIAN PROTEIN VOLUME OF PRODUCT IN
COMMERCE 27,694,240 lbs
Date: August 6, 2006 at 6:14 pm PST
PRODUCT
Bulk custom dairy feds manufactured from concentrates, Recall # V-113-6
CODE
All dairy feeds produced between 2/1/05 and 6/16/06 and containing H. J.
Baker recalled feed products.
RECALLING FIRM/MANUFACTURER
Vita Plus Corp., Gagetown, MI, by visit beginning on June 21, 2006. Firm
initiated recall is complete.
REASON
The feed was manufactured from materials that may have been contaminated
with mammalian protein.
VOLUME OF PRODUCT IN COMMERCE
27,694,240 lbs
DISTRIBUTION
MI


END OF ENFORCEMENT REPORT FOR AUGUST 2, 2006

###


http://www.fda.gov/bbs/topics/enforce/2006/ENF00963.html


Subject: MAD COW FEED RECALL AL AND FL VOLUME OF PRODUCT IN COMMERCE 125
TONS Products manufactured from 02/01/2005 until 06/06/2006
Date: August 6, 2006 at 6:16 pm PST
PRODUCT
a) CO-OP 32% Sinking Catfish, Recall # V-100-6;
b) Performance Sheep Pell W/Decox/A/N, medicated,
net wt. 50 lbs, Recall # V-101-6;
c) Pro 40% Swine Conc Meal -- 50 lb, Recall # V-102-6;
d) CO-OP 32% Sinking Catfish Food Medicated,
Recall # V-103-6;
e) "Big Jim's" BBB Deer Ration, Big Buck Blend,
Recall # V-104-6;
f) CO-OP 40% Hog Supplement Medicated Pelleted,
Tylosin 100 grams/ton, 50 lb. bag, Recall # V-105-6;
g) Pig Starter Pell II, 18% W/MCDX Medicated 282020,
Carbadox -- 0.0055%, Recall # V-106-6;
h) CO-OP STARTER-GROWER CRUMBLES, Complete
Feed for Chickens from Hatch to 20 Weeks, Medicated,
Bacitracin Methylene Disalicylate, 25 and 50 Lbs,
Recall # V-107-6;
i) CO-OP LAYING PELLETS, Complete Feed for Laying
Chickens, Recall # 108-6;
j) CO-OP LAYING CRUMBLES, Recall # V-109-6;
k) CO-OP QUAIL FLIGHT CONDITIONER MEDICATED,
net wt 50 Lbs, Recall # V-110-6;
l) CO-OP QUAIL STARTER MEDICATED, Net Wt. 50 Lbs,
Recall # V-111-6;
m) CO-OP QUAIL GROWER MEDICATED, 50 Lbs,
Recall # V-112-6
CODE
Product manufactured from 02/01/2005 until 06/06/2006
RECALLING FIRM/MANUFACTURER
Alabama Farmers Cooperative, Inc., Decatur, AL, by telephone, fax, email and
visit on June 9, 2006. FDA initiated recall is complete.
REASON
Animal and fish feeds which were possibly contaminated with ruminant based
protein not labeled as "Do not feed to ruminants".
VOLUME OF PRODUCT IN COMMERCE
125 tons
DISTRIBUTION
AL and FL


END OF ENFORCEMENT REPORT FOR AUGUST 2, 2006

###


http://www.fda.gov/bbs/topics/enforce/2006/ENF00963.html


Subject: MAD COW FEED RECALL KY VOLUME OF PRODUCT IN COMMERCE ?????
Date: August 6, 2006 at 6:19 pm PST
PRODUCT
Bulk custom made dairy feed, Recall # V-114-6
CODE
None
RECALLING FIRM/MANUFACTURER
Burkmann Feeds LLC, Glasgow, KY, by letter on July 14, 2006. Firm initiated
recall is ongoing.
REASON
Custom made feeds contain ingredient called Pro-Lak, which may contain
ruminant derived meat and bone meal.
VOLUME OF PRODUCT IN COMMERCE
?????
DISTRIBUTION
KY
END OF ENFORCEMENT REPORT FOR AUGUST 2, 2006

###


http://www.fda.gov/bbs/topics/enforce/2006/ENF00963.html


CJD WATCH MESSAGE BOARD
TSS
MAD COW FEED RECALL USA EQUALS 10,878.06 TONS NATIONWIDE
Sun Jul 16, 2006 09:22
71.248.128.67


RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINE -- CLASS II
______________________________
PRODUCT
a) PRO-LAK, bulk weight, Protein Concentrate for Lactating Dairy Animals,
Recall # V-079-6;
b) ProAmino II, FOR PREFRESH AND LACTATING COWS, net weight 50lb (22.6 kg),
Recall # V-080-6;
c) PRO-PAK, MARINE & ANIMAL PROTEIN CONCENTRATE FOR USE IN ANIMAL
FEED, Recall # V-081-6;
d) Feather Meal, Recall # V-082-6
CODE
a) Bulk
b) None
c) Bulk
d) Bulk
RECALLING FIRM/MANUFACTURER
H. J. Baker & Bro., Inc., Albertville, AL, by telephone on June 15, 2006 and
by press release on June 16, 2006. Firm initiated recall is ongoing.
REASON
Possible contamination of animal feeds with ruminent derived meat and bone
meal.
VOLUME OF PRODUCT IN COMMERCE
10,878.06 tons
DISTRIBUTION
Nationwide

END OF ENFORCEMENT REPORT FOR July 12, 2006

###



http://www.fda.gov/bbs/topics/enforce/2006/ENF00960.html


Subject: MAD COW FEED BAN WARNING LETTER ISSUED MAY 17, 2006
Date: June 27, 2006 at 7:42 am PST
Public Health Service
Food and Drug Administration

New Orleans District
297 Plus Park Blvd.
Nashville, TN 37217

Telephone: 615-781-5380
Fax: 615-781-5391



May 17, 2006

WARNING LETTER NO. 2006-NOL-06

FEDERAL EXPRESS
OVERNIGHT DELIVERY

Mr. William Shirley, Jr., Owner
Louisiana.DBA Riegel By-Products
2621 State Street
Dallas, Texas 75204

Dear Mr. Shirley:

On February 12, 17, 21, and 22, 2006, a U.S. Food & Drug Administration
(FDA) investigator inspected your rendering plant, located at 509 Fortson
Street, Shreveport, Louisiana. The inspection revealed significant
deviations from the requirements set forth in Title 21, Code of Federal
Regulations, Part 589.2000 [21 CFR 589.2000], Animal Proteins Prohibited in
Ruminant Feed. This regulation is intended to prevent the establishment and
amplification of Bovine Spongiform Encephalopathy (BSE). You failed to
follow the requirements of this regulation; products being manufactured and
distributed by your facility are misbranded within the meaning of Section
403(a)(1) [21 USC 343(a)(1)] of the Federal Food, Drug, and Cosmetic Act
(the Act).

Our investigation found you failed to provide measures, including sufficient
written procedures, to prevent commingling or cross-contamination and to
maintain sufficient written procedures [21 CFR 589.2000(e)] because:

You failed to use clean-out procedures or other means adequate to prevent
carryover of protein derived from mammalian tissues into animal protein or
feeds which may be used for ruminants. For example, your facility uses the
same equipment to process mammalian and poultry tissues. However, you use
only hot water to clean the cookers between processing tissues from each
species. You do not clean the auger, hammer mill, grinder, and spouts after
processing mammalian tissues.

You failed to maintain written procedures specifying the clean-out
procedures or other means to prevent carryover of protein derived from
mammalian tissues into feeds which may be used for ruminants.

As a result . the poultry meal you manufacture may contain protein derived
from mammalian tissues prohibited in ruminant feed. Pursuant to 21 CFR
589.2000(e)(1)(i), any products containing or may contain protein derived
from mammalian tissues must be labeled, "Do not feed to cattle or other
ruminants." Since you failed to label a product which may contain protein
derived from mammalian tissues with the required cautionary statement. the
poultry meal is misbranded under Section 403(a)(1) [21 USC 343(a)(1)] of the
Act.

This letter is not intended as an all-inclusive list of violations at your
facility. As a manufacturer of materials intended for animal feed use, you
are responsible for ensuring your overall operation and the products you
manufacture and distribute are in compliance with the law. You should take
prompt action to correct these violations, and you should establish a system
whereby violations do not recur. Failure to promptly correct these
violations may result in regulatory action, such as seizure and/or
injunction, without further notice.

You should notify this office in writing within 15 working days of receiving
this letter, outlining the specific steps you have taken to bring your firm
into compliance with the law. Your response should include an explanation of
each step taken to correct the violations and prevent their recurrence. If
corrective action cannot be completed within 15 working days, state the
reason for the delay and the date by which the corrections will be
completed. Include copies of any available documentation demonstrating
corrections have been made.

Your reply should be directed to Mark W. Rivero, Compliance Officer, U.S.
Food and Drug Administration, 2424 Edenborn Avenue, Suite 410, Metairie,
Louisiana 70001. If you have questions regarding any issue in this letter,
please contact Mr. Rivero at (504) 219-8818, extension 103.

Sincerely,

/S

Carol S. Sanchez
Acting District Director
New Orleans District


http://www.fda.gov/foi/warning_letters/g5883d.htm


SINCE THE LAST TIME I REPORTED :




Subject: USDA FSIS QUARTERLY ENFORCEMENT REPORT (BSE) July 1, 2005 through September 30, 2005
Date: March 20, 2006 at 12:58 pm PST




YOU can see that report at the bottom of this update.




UPDATEs AS FOLLOWS ;





UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE QUARTERLY ENFORCEMENT REPORT July 1, 2006 through September 30, 2006




snip...




Table 5. Administrative Actions: Large HACCP Plants (7/01/06 to 9/30/06)

Administrative Actions Pending or Taken at Large HACCP Plants [includes actions initiated in prior quarters]




CARGILL MEAT SOLUTIONS 00086K M DODGE CITY, KS



On 6/15/06, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...



EXCEL CORP 00086R M FORT MORGAN, CO



On 8/11/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8. On 12/22/04, plant appealed the withholding action. Appeal was denied on 1/25/05.




snip...



TYSON FRESH MEATS INC. 09268 M PASCO, WA
X
X
On 7/28/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.

TYSON FRESH MEATS INC. 00245D M EMPORIA, KS
X
X
On 12/23/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.

TYSON FRESH MEATS INC. 00245L M LEXINGTON, NE
X
X
On 3/10/05, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...


Table 6. Administrative Actions: Small HACCP Plants (7/01/06 to 9/30/06)

Administrative Actions Pending or Taken at Small HACCP Plants [includes actions initiated in prior quarters]




SSOP
HACCP
SPS
INH
INT
Other
LOI
LOW

BOOKER PACKING COMPANY 07162 M BOOKER, TX
6/2/06
6/5/06
X
X
9/19/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



SSOP
HACCP
SPS
INH
INT
Other
LOI
LOW

GULF PACKING COMPANY 00696 M00696 P SAN BENITO, TX
2/25/06
2/26/06
X
X
8/31/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



HI COUNTRY BEEF JERKY 01248 M01248 P LINCOLN, MT
3/24/06
4/14/06
X
X
X
X
8/31/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



NORTHERN PACKING COMPANY INC. 00571 M BRIAR HILL, NY
12/9/05
12/23/05
X
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



WEST MISSOURI BEEF 05821 M ROCKVILLE, MO
3/2/06
3/16/06
4/13/06
4/17/06
X
X
X
8/15/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]




GIBSON PACKING COMPANY 05843 M05843 P SEYMOUR, MO
9/21/06
X
X
X
X
Plant failed to meet regulatory requirements for Escherichia coli Biotype 1 (E. coli). The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



SSOP
HACCP
SPS
INH
INT
Other
LOI
LOW

HORMANN MEAT COMPANY 05544 M05544 P FAIR GROVE, MO
6/15/06
6/22/06
X
X
X
9/26/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



ROCK CREEK SLAUGHTER CO. 09150 M09150 P LOOKOUT MOUNTAIN, GA
3/16/06
4/14/06
6/30/06
7/5/06
X
X
X
X
8/11/06
On 3/16/06, an enforcement action concerning failure to meet regulatory requirements for Escherichia coli Biotype 1 (E.coli) was issued. The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



THEURER'S QUALITY MEATS, INC. 31647 M31647 P LEWISTON, UT
7/25/05
7/29/05
X
X
7/25/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...


http://www.fsis.usda.gov/PDF/QER_Q4_FY2006.pdf





UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE QUARTERLY ENFORCEMENT REPORT April 1, 2006 through June 30, 2006


Table 5. Administrative Actions: Large HACCP Plants (4/01/06 to 6/30/06)




CARGILL MEAT SOLUTIONS 00086K M DODGE CITY, KS
X
X
On 6/15/06, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...



EXCEL CORP 00086R M FORT MORGAN, CO
2/22/05
X
X
On 8/11/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8. On

12/22/04, plant appealed the withholding action. Appeal was denied on 1/25/05.




snip...



TYSON FRESH MEATS INC 00245L M LEXINGTON, NE
X
X
On 3/10/05, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...



SSOP
HACCP
SPS
INH
INT
Other
LOI
LOW

TYSON FRESH MEATS INC. 09268 M PASCO, WA
X
X
On 7/28/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.

TYSON FRESH MEATS INC. 00245D M EMPORIA, KS
X
X
On 12/23/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.





snip...



Administrative Actions Pending or Taken at Small HACCP Plants [includes actions initiated in prior quarters]






BOOKER PACKING COMPANY 07162 M BOOKER, TX
4/13/06
4/19/06
X
X
Plant failed to meet regulatory requirements for Escherichia coli Biotype 1 (E. coli).

6/2/06
6/5/06
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.





snip...



GULF PACKING COMPANY 00696 M00696 P SAN BENITO, TX
2/25/06
2/26/06
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...


???

3/24/06
4/14/06

X
X
X



The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.


snip...



NORTHERN PACKING COMPANY INC. 00571 M BRIAR HILL, NY
12/9/05
12/23/05
X
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



WEST MISSOURI BEEF 05821 M ROCKVILLE, MO
3/2/06
3/16/06
4/13/06
4/17/06
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...


C & C MEAT SALES, INC., 18494 M18494 P, DURHAM, NC ... FAILURE TO COMPLY CONCERNING SRM MATERIAL.


snip...



FRESH FARMS BEEF 18579 M RUTLAND, VT
12/16/05
12/28/05
X
X
X
4/13/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.

FRONTIER FOODS & COLD STORAGE, INC 20741 M20741 P EL PASO, TX
5/31/06
X
X
On 6/8/06, DM closed case by firm's requested voluntary withdrawal. The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



HORMANN MEAT COMPANY 05544 M05544 P FAIR GROVE, MO
6/15/06
6/22/06
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



RANDALL MEAT COMPANY 10669 M HOT SPRINGS, AR
7/1/05
7/28/05
10/12/05
10/24/05
X
X
X
5/19/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.

ROCK CREEK SLAUGHTER CO. 09150 M09150 P LOOKOUT MOUNTAIN, GA
3/16/06
4/14/06
6/30/06
X
X
X
X
On 3/16/06, an enforcement action concerning failure to meet regulatory requirements for Escherichia coli Biotype 1 (E.coli) was issued. The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...


SAVORY CONNECTION, INC., 31764 M31764 P, SELINGSGROVE, PA. ... FAILURE TO COMPLY CONCERNING SRM MATERIAL.


snip...


STEAK MASTER, 21159 M21159 P, ELWOOD, NE. ... FAILURE TO COMPLY CONCERNING SRM MATERIAL.


snip...




THE MEAT SHOP 31561 M BENSON, VT
8/18/05
9/6/05
9/9/05
X
X
X
X
X
4/4/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.

THEURER'S QUALITY MEATS, INC. 31647 M31647 P LEWISTON, UT
7/25/05
7/29/05
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



WALNUT VALLEY PACKING L.L.C. 32007 M32007 P EL DORADO, KS
12/15/05
12/30/05
X
X
X
5/4/06
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



http://www.fsis.usda.gov/PDF/QER_Q3_FY2006.pdf





UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE QUARTERLY ENFORCEMENT REPORT January 1, 2006 through March 31, 2006


Table 5. Administrative Actions: Large HACCP Plants (1/01/06 to 3/31/06)



CARGILL MEAT SOLUTIONS 00086K M DODGE CITY, KS
X
X
3/13/06
On 10/11/05, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.





snip...



EXCEL CORP. 00086R M FORT MORGAN, CO
8/11/04
2/22/05
X
X
On 8/11/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.

On 12/22/04, plant appealed the withholding action. Appeal was denied on 1/25/05.




snip...



TYSON FRESH MEATS INC. 00245L M
3/12/04
3/18/04
X

LEXINGTON, NE

X
X
On 3/10/05, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...



TYSON FRESH MEATS INC. 09268 M PASCO, WA
X
X
On 7/28/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.

TYSON FRESH MEATS INC. 00245D M EMPORIA, KS
X
X
On 12/23/04, a withholding action concerning labels for Advanced Meat Recovery System product was taken in accordance with 9 CFR Part 500.8.




snip...





Administrative Actions Pending or Taken at Small HACCP Plants [includes actions initiated in prior quarters]





GULF PACKING COMPANY, 00696 M00696 P, SAN BENITO, TX, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


HI COUNTRY BEEF JERKY, 01248 M01248 P, LINCOLN, MT, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


HITCHIN POST STEAK COMPANY, 20773 M20773 P, KANSAS CITY, KS, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...



NORTHERN PACKING COMPANY INC. 00571 M BRIAR HILL, NY
12/9/05
12/23/05
X
X
X
X
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



ROCK CREEK SLAUGHTER CO., 09150 M09150 P, FAIRBURY, NE, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...



WEST MISSOURI BEEF 05821 M ROCKVILLE, MO
3/2/06
3/16/06
X
X
X
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



Table 7. Administrative Actions: Very Small HACCP Plants (1/01/06 to 3/31/06)




A.J. CEKAK'S MEAT MARKET 21562 M ORD. NE, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL



snip...



ALTA VISTA LOCKER 31931 M ALTA VISTA, KS, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...



C&C MEAT SALES, INC. 18494 M18494 P UPPER MARLBORO, MD
2/27/06
3/16/06
X
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



FRESH FARMS BEEF 18579 M RUTLAND, VT
12/16/05
12/28/05
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



H AND P MEATS 21352 M SOUTH PITTSBURG, TN
7/28/05
8/8/05
8/17/05
8/19/05
X
X
3/6/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



PARADISE LOCKER MEATS 31865 M31865 P TRIMBLE, MO
9/21/05
10/7/05
X
X
1/13/06
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.

PARAGON SPRAY DRYING, L.L.C. 31762 M31762 P WAUKON, IA
9/6/05
9/12/05
X
X
X
2/9/06
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



RANDALL MEAT COMPANY 10669 M HOT SPRINGS, AR
7/1/05
7/28/05
10/12/05
10/24/05
X
X
X
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



SAVORY CONNECTION, INC. 31764 M31764 P SELINGSGROVE, PA
3/14/06
3/31/06
X
X
X
The enforcement action included, as basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...




STEAK MASTER, 21159 M21159 P, ELWOOD, NW, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


TEARS MARKET, 04535 M04535 P, PENN YAN, NY, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


THE MEAT SHOP, 31561 M BENSON, VT, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


THEURER'S QUALITY MEATS, INC. 31647 M31647 P, LEWISTON, UT, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...


TOOELE VALLEY MEATS 20594 M20594 P, GRANTSVILLE, UT, ... FAILURE TO COMPLY CONCERNING SRM MATERIAL


snip...



WALNUT VALLEY PACKING L.L.C. 32007 M32007 P EL DORADO, KS
12/15/05
12/30/05
X
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.




snip...



WILLIAM. G. MEST PACKING CO. 04431 M STRYKERSVILLE, NY
2/2/06
2/23/06
X
X
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material. On 3/21/06, NOIE was modified and

reissued. On 6/29/06, NOIE was

rescinded.

YODER BROTHERS MEAT PROCESSING 17301 M PARIS, TN
10/3/05
10/12/05
X
X
2/23/06
The enforcement action included, as a basis, failure of the establishment to comply with Agency requirements concerning specified risk material.





snip...





http://www.fsis.usda.gov/PDF/QER_Q1_FY2006.pdf






UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE QUARTERLY ENFORCEMENT REPORT October 1, 2005 through December 31, 2005



SRM REMOVAL USA


UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE
QUARTERLY ENFORCEMENT REPORT October 1, 2005 through December 31, 2005


snip....


CARGILL MEAT SOLUTIONS 00086K M DODGE CITY, KS X X On 10/11/05, a
withholding action concerning labels for Advanced Meat Recovery System
product was taken in accordance with 9 CFR Part 500.8.


EXCEL CORP 00086R M FORT MORGAN, CO 2/22/05 X X On 8/11/04, a withholding
action concerning labels for Advanced Meat Recovery System product was taken
in accordance with 9 CFR Part 500.8. On 12/22/04, plant appealed the
withholding action. Appeal was denied on 1/25/05.


00245L M LEXINGTON, NE 3/12/04 3/18/04 X 5/4/05 X X On 3/10/05, a
withholding action concerning labels for Advanced Meat Recovery System
product was taken in accordance with 9 CFR Part 500.8.

9/16/05 9/29/05 X X TYSON FRESH MEATS INC. 09268 M PASCO, WA X X On 7/28/04,
a withholding action concerning labels for Advanced Meat Recovery System
product was taken in accordance with 9 CFR Part 500.8.

TYSON FRESH MEATS INC. X X 00245D M EMPORIA, KS On 12/23/04, a withholding
action concerning labels for Advanced Meat Recovery System product was taken
in accordance with 9 CFR Part 500.8.


DESERET MEAT 04852 M SPANISH FORK, UT 7/20/05 8/1/05 X X 12/29/05 The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


NORTHERN PACKING COMPANY INC. 00571 M BRIAR HILL, NY 12/9/05 12/23/05 X X X
X The enforcement action included, as a basis, failure of the establishment
to comply with Agency requirements concerning specified risk material.


A.J. CEKAK'S MEAT MARKET 9/1/05 9/20/05 X X X On 9/1/05, an enforcement
action
21562 M
concerning failure to meet regulatory ORD, NE requirements for Escherichia
coli Biotype 1 (E. coli) was taken. The enforcement action included, as a
basis, failure of the establishment to comply with Agency requirements
concerning specified risk material.


ALTA VISTA LOCKER
10/5/05 10/26/05 X X The enforcement action included, as a 31931 M basis,
failure of the establishment toALTA VISTA, KS comply with Agency
requirements
concerning specified risk material.


BROWN'S PROCESSING 13100 M13100 P ELSBERRY, MO 8/8/05 8/16/05 X X X 11/16/05
The enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


CHAMPLAIN BEEF INC 2/28/05 3/4/05 3/8/05 X X X
08547 M
WHITEHALL, NY
10/17/05 X X X The enforcement action included, as a basis, failure of the
establishment to comply with Agency requirements concerning specified risk
material.


FIVE STAR PACK INC. 9/1/05 9/9/05 X X 12/29/05 On 9/1/05, an enforcement
action
08725 M08725 P
concerning failure to meet regulatory GOLDEN CITY, MO requirements for
Escherichia coli Biotype 1 (E. coli) was taken. The enforcement action
included, as a basis, failure of the establishment to comply with Agency
requirements concerning specified risk material. FRESH FARMS BEEF 12/16/05
12/28/05 X X X The enforcement action included, as a 18579 M basis, failure
of the establishment toRUTLAND, VT comply with Agency requirements
concerning specified risk material.


GOETZ AND SONS WESTERN 11/15/05 11/23/05 12/1/05 X X
MEATS INC
06245 M06245 P
EVERETT, WA
12/17/05 12/28/05 X X X On 12/17/05, firm violated a regulatory control
action by selling U.S.D.A retained product.


H AND P MEATS 21352 M SOUTH PITTSBURG, TN 7/28/05 8/8/05 8/17/05 8/19/05 X X
The enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


HOPKINS PACKING COMPANY 11069 M BLACKFOOT, ID 7/28/05 8/1/05 X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


NORTHWEST PREMIUM MEATS LLC 11032 M11032 P NAMPA, ID 7/26/05 7/29/05 X X
11/15/05 The enforcement action included, as a basis, failure of the
establishment to comply with Agency requirements concerning specified risk
material.


PARADISE LOCKER MEATS 31865 M31865 P TRIMBLE, MO 9/21/05 10/7/05 X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material. PARAGON
SPRAY DRYING, LLC 31762 M31762 P WAUKON, IA 9/6/05 9/12/05 X X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


RANDALL MEAT COMPANY 10669 M HOT SPRINGS, AR 7/1/05 7/28/05 10/12/05
10/24/05 X X X The enforcement action included, as a basis, failure of the
establishment to comply with Agency requirements concerning specified risk
material.


S & S MEAT COMPANY 01046 M01046 P KANSAS CITY, MO 8/4/05 8/19/05 X X
11/16/05 The enforcement action included, as a basis, failure of the
establishment to comply with Agency requirements concerning specified risk
material.


STEAK MASTER 21159 M21159 P ELWOOD, NE 11/4/05 11/17/05 X X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


THE MEAT SHOP 31561 M BENSON, VT 8/18/05 9/6/05 9/9/05 X X X X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


THEURER'S QUALITY MEATS, INC 31647 M31647 P LEWISTON, UT 7/27/05 7/29/05 X X
The enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


TOOELE VALLEY MEATS 20594 M20594 P GRANTSVILLE, UT 7/25/05 8/1/05 X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


WALNUT VALLEY PACKING LLC 32007 M32007 P EL DORADO, KS 12/15/05 12/30/05 X X
X The enforcement action included, as a basis, failure of the establishment
to comply with Agency requirements concerning specified risk material.


YODER BROTHERS MEAT PROCESSING 17301 M PARIS, TN 10/3/05 10/12/05 X X The
enforcement action included, as a basis, failure of the establishment to
comply with Agency requirements concerning specified risk material.


full text 54 pages ;


http://www.fsis.usda.gov/PDF/QER_Q1_FY2006.pdf






Subject: USDA FSIS QUARTERLY ENFORCEMENT REPORT (BSE) July 1, 2005 through September 30, 2005
Date: March 20, 2006 at 12:58 pm PST


UNITED STATES DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE QUARTERLY ENFORCEMENT REPORT July 1, 2005 through September 30, 2005


snip...


Administrative Actions Pending or Taken at Small HACCP Plants [includes actions initiated in prior quarters]



snip...


DESERET MEAT 04852 M SPANISH FORK, UT
07/27/05
08/01/05
X
X
On 7/27/05, a suspension action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3.



snip...


Administrative Actions Pending or Taken at Small HACCP Plants [includes actions initiated in prior quarters]



snip...


MONTEBELLO MEAT PROCESSING, INC 19075 M19075 P MANATI, PR
08/01/05
08/18/05
X
X
X
09/26/05
On 8/1/05, an enforcement action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.



snip...

Table 7. Administrative Actions: Very Small HACCP Plants (7/01/05 to 9/30/05)


snip...


A.J. CEKAK'S MEAT MARKET 09/01/05 09/20/05 On 9/1/05, an enforcement action

21562 M

concerning failure to meet regulatory ORD, NE requirements for Escherichia coli X X X Biotype 1 (E. coli) and Bovine Spongiform Encephalopathy/Specified Risk Material was taken in accordance with 9 CFR Part 500.4.


snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]



snip...


BROWN'S PROCESSING 13100 M13100 P ELSBERRY, MO
08/08/05
08/16/05
X
X
X
On 8/8/05, an enforcement action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.



snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]



snip...


FIVE STAR PACK INC. 08725 M08725 P GOLDEN CITY, MO 09/01/05 09/09/05 X X On 9/1/05, an enforcement action concerning failure to meet regulatory requirements for Escherichia coli Biotype 1 (E. coli) and Bovine Spongiform Encephalopathy/Specified Risk Material was taken in accordance with 9 CFR Part 500.4.


snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]



snip...


H AND P MEATS 21352 M SOUTH PITTSBURG, TN 07/28/05 08/08/05 08/17/05 08/19/05 X X On 8/17/05, a suspension action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3.


snip...


HOPKINS PACKING COMPANY 11069 M BLACKFOOT, ID
07/28/05
08/01/05
X
X
On 7/28/05, a suspension action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3.



snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]



snip...


NORTHWEST PREMIUM MEATS LLC 11032 M11032 P NAMPA, ID 07/26/05 07/29/05 X X On 7/26/05, a suspension action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3.


snip...


PARADISE LOCKER MEATS 31865 M31865 P TRIMBLE, MO
09/21/05
X
X
On 9/21/05, an enforcement action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.

PARAGON SPRAY DRYING, LLC 31792 M31792 P WAUKON, IA
09/06/05
09/12/05
X
X
X
On 9/6/05, an enforcement action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.



snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]



snip...


RANDALL MEAT COMPANY 10669 M HOT SPRINGS, AR
07/01/05
07/28/05
X
X
X
On 7/1/05, an enforcement action concerning Bovine Spongiform Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.



snip...


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]


snip...


08/04/05

08/19/05

On 8/4/05,

an enforcement action 01046 M01046 P concerning Bovine SpongiformKANSAS CITY, MO X X Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.4.


Administrative Actions Pending or Taken at Very Small HACCP Plants [includes actions initiated in prior quarters]


snip...


THE MEAT SHOP 08/18/05 09/06/05

09/09/05

On 9/6/05, a suspension action 31561 M concerning Bovine SpongiformBENSON, VT Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3. XX X X X


THEURER'S QUALITY MEATS, 07/27/05 07/29/05

On 7/27/05, a suspension action INC concerning Bovine Spongiform31647 M31647 P Encephalopathy and Specified Risk X X

LEWISTON, UT Material was taken in accordance with 9 CFR Part 500.3.


TOOELE VALLEY MEATS 07/25/05 08/01/05

On 7/25/05, a suspension action 20594 M20594 Pconcerning Bovine Spongiform

GRANTSVILLE, UT X X Encephalopathy and Specified Risk Material was taken in accordance with 9 CFR Part 500.3.


snip...


52 pages



http://www.fsis.usda.gov/PDF/QER_Q4_FY2005.pdf




PREVIOUS


http://www.fsis.usda.gov/PDF/QER_Q3_FY2005.pdf




http://www.fsis.usda.gov/PDF/QER_Q2_FY2005.pdf




http://www.fsis.usda.gov/PDF/QER_Q1_FY2005.pdf



P04.27

Experimental BSE Infection of Non-human Primates: Efficacy of the Oral Route

Holznagel, E1; Yutzy, B1; Deslys, J-P2; Lasmézas, C2; Pocchiari, M3; Ingrosso, L3; Bierke, P4; Schulz-Schaeffer, W5; Motzkus, D6; Hunsmann, G6; Löwer, J1 1Paul-Ehrlich-Institut, Germany; 2Commissariat à l´Energie Atomique, France; 3Instituto Superiore di Sanità, Italy; 4Swedish Institute for Infectious Disease control, Sweden; 5Georg August University, Germany; 6German Primate Center, Germany

Background:

In 2001, a study was initiated in primates to assess the risk for humans to contract BSE through contaminated food. For this purpose, BSE brain was titrated in cynomolgus monkeys.

Aims:

The primary objective is the determination of the minimal infectious dose (MID50) for oral exposure to BSE in a simian model, and, by in doing this, to assess the risk for humans. Secondly, we aimed at examining the course of the disease to identify possible biomarkers.

Methods:

Groups with six monkeys each were orally dosed with lowering amounts of BSE brain: 16g, 5g, 0.5g, 0.05g, and 0.005g. In a second titration study, animals were intracerebrally (i.c.) dosed (50, 5, 0.5, 0.05, and 0.005 mg).

Results:

In an ongoing study, a considerable number of high-dosed macaques already developed simian vCJD upon oral or intracerebral exposure or are at the onset of the clinical phase. However, there are differences in the clinical course between orally and intracerebrally infected animals that may influence the detection of biomarkers.

Conclusions:

Simian vCJD can be easily triggered in cynomolgus monkeys on the oral route using less than 5 g BSE brain homogenate. The difference in the incubation period between 5 g oral and 5 mg i.c. is only 1 year (5 years versus 4 years). However, there are rapid progressors among orally dosed monkeys that develop simian v CJD as fast as intracerebrally inoculated animals.

The work referenced was performed in partial fulfilment of the study "BSE in primates" supported by the EU (QLK1-2002-01096).


http://www.prion2007.com/pdf/Prion%20Book%20of%20Abstracts.pdf


IS THERE A SCRAPIE-LIKE DISEASE IN CATTLE ?


In April of 1985, a mink rancher in Wisconsin reported a debilitating
neurologic disease in his herd which we diagnosed as TME by histopathologic
findings confirmed by experimental transmission to mink and squirrel
monkeys. The rancher was a ''dead stock'' feeder using mostly (>95%) downer
or dead dairy cattle and a few horses. She had never been fed.

We believe that these findings may indicate the presence of a previously
unrecognized scrapie-like disease in cattle and wish to alert dairy
practitioners to this possibility.


snip...


PROCEEDINGS OF THE SEVENTH ANNUAL WESTERN CONFERENCE FOR FOOD ANIMAL
VETERINARY MEDICINE, University of Arizona, March 17-19, 1986


http://www.bseinquiry.gov.uk/files/mb/m09a/tab01.pdf


OBSERVATIONS AND RESULTS

A New Incidence of TME. In April of 1985, a mink rancher in Stetsonville, Wisconsin
reported that many of his mink were "acting funny", and some had died. At this time, we
visited the farm and found that approximately 10% of all adult mink were showing
typical signs of TME: insidious onset characterized by subtle behavioral changes, loss of
normal habits of cleanliness, deposition of droppings throughout the pen rather than in a
single area, hyperexcitability, difficulty in chewing and swallowing, and tails arched over
their _backs like squirrels. These signs were followed by progressive deterioration of
neurologic function beginning with locomoior incoordination, long periods of somnolence
in which the affected mink would stand motionless with its head in the corner of the
cage, complete debilitation, and death. Over the next 8-10 weeks, approximately 40% of
all the adult mink on the farm died from TME.

Since previous incidences of TME were associated with common or shared feeding
practices, we obtained a careful history of feed ingredients used over the past 12-18
months. The rancher was a "dead stock" feeder using mostly (>95%) downer or dead dairy
cattle and a few horses. Sheep had never been fed.

Experimental Transmission. The clinical diagnosis of TME was confirmed by
histopaihologic examination and by experimental transmission to mink after incubation
periods of four months. To investigate the possible involvement of cattle in this disease
cycle, two six-week old castrated Holstein bull calves were inoculated intracerebrally
with a brain suspension from affected mink. Each developed a fatal spongiform
encephalopathy after incubation periods of 18 and 19 months.

DISCUSSION

These findings suggest that TME may result from feeding mink infected cattle and
we have alerted bovine practitioners that there may exist an as yet unrecognized
scrapie-like disease of cattle in the United States (Marsh and Hartsough, 1986). A new
bovine spongiform encephalopathy has recently been reported in England (Wells et al.,
1987), and investigators are presently studying its transmissibility and possible
relationship to scrapie. Because this new bovine disease in England is characterized by
behavioral changes, hyperexcitability, and agressiveness, it is very likely it would be
confused with rabies in the United Stales and not be diagnosed. Presently, brains from
cattle in the United States which are suspected of rabies infection are only tested with
anti-rabies virus antibody and are not examined histopathologically for lesions of
spongiform encephalopathy.

We are presently pursuing additional studies to further examine the possible
involvement of cattle in the epidemiology of TME. One of these is the backpassage of
our experimental bovine encephalopathy to mink. Because (here are as yet no agent-
specific proteins or nucleic acids identified for these transmissible neuropathogens, one
means of distinguishing them is by animal passage and selection of the biotype which
grows best in a particular host. This procedure has been used to separate hamster-
adapted and mink-udapted TME agents (Marsh and Hanson, 1979). The intracerebral
backpassage of the experimental bovine agent resulted in incubations of only four months
indicating no de-adaptation of the Stetsonville agent for mink after bovine passage.
Mink fed infected bovine brain remain normal after six months. It will be essential to
demonstrate oral transmission fiom bovine to mink it this proposed epidemiologic
association is to be confirmed.

ACKNOWLEDGEMENTS
These studies were supported by the College of Agricultural and Life Sciences,
University of Wisconsin-Madison and by a grant (85-CRCR-1-1812) from the United
States Department of Agriculture. The authors also wish to acknowledge the help and
encouragement of Robert Hanson who died during the course of these investigations.

REFERENCES

Burger, D. and Hartsough, G.R. 1965. Encephalopathy of mink. II. Experimental and
natural transmission. J. Infec. Dis. 115:393-399.
Hanson, R.P., Eckroade, R.3., Marsh, R.F., ZuRhein, C.M., Kanitz, C.L. and Gustatson,
D.P. 1971. Susceptibility of mink to sheep scrapie. Science 172:859-861.
Hansough, G.R. and Burger, D. 1965. Encephalopathy of mink. I. Epizoociologic and
clinical observations. 3. Infec. Dis. 115:387-392.
Marsh, R.F. and Hanson, R.P. 1969. Physical and chemical properties of the
transmissible mink encephalopathy agent. 3. ViroL 3:176-180.
Marsh, R.F. and Hanson, R.P. 1979. On the origin of transmissible mink
encephalopathy. In Hadlow, W.J. and Prusiner, S.P. (eds.) Slow transmissible
diseases of the nervous system. Vol. 1, Academic Press, New York, pp 451-460.
Marsh, R.F. and Hartsough, G.R. 1986. Is there a scrapie-like disease in cattle?
Proceedings of the Seventh Annual Western Conference for Food Animal Veterinary
Medicine. University of Arizona, pp 20.
Wells, G.A.H., Scott, A.C., Johnson, C.T., Cunning, R.F., Hancock, R.D., Jeffrey, M.,
Dawson, M. and Bradley, R. 1987. A novel progressive spongiform encephalopathy
in cattle. Vet. Rec. 121:419-420.

MARSH

http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf


Saturday, December 01, 2007

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model
Volume 13, Number 12–December 2007
Research

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle andL-type Bovine Spongiform Encephalopathy in a Mouse Model

Thierry Baron,* Anna Bencsik,* Anne-Gaëlle Biacabe,* Eric Morignat,* andRichard A. Bessen†*Agence Française de Sécurité Sanitaire des Aliments–Lyon, Lyon, France; and†Montana State University, Bozeman, Montana, USA

Abstract

Transmissible mink encepholapathy (TME) is a foodborne transmissible spongiform encephalopathy (TSE) of ranch-raised mink; infection with a ruminant TSE has been proposed as the cause, but the precise origin of TME is unknown. To compare the phenotypes of each TSE, bovine-passaged TME isolate and 3 distinct natural bovine spongiform encephalopathy (BSE) agents (typical BSE, H-type BSE, and L-type BSE) were inoculated into an ovine transgenic mouse line (TgOvPrP4). Transgenic mice were susceptible to infection with bovine-passaged TME, typical BSE, and L-type BSE but not to H-type BSE. Based on survival periods, brain lesions profiles, disease-associated prion protein brain distribution, and biochemical properties of protease-resistant prion protein, typical BSE had a distint phenotype in ovine transgenic mice compared to L-type BSE and bovine TME.The similar phenotypic properties of L-type BSE and bovine TME in TgOvPrP4mice suggest that L-type BSE is a much more likely candidate for the origin of TME than is typical BSE.

snip...

Conclusion

These studies provide experimental evidence that the Stetsonville TME agentis distinct from typical BSE but has phenotypic similarities to L-type BSE in TgOvPrP4 mice. Our conclusion is that L-type BSE is a more likely candidate for a bovine source of TME infection than typical BSE. In the scenario that a ruminant TSE is the source for TME infection in mink, this would be a second example of transmission of a TS
 
continued ;


Saturday, December 01, 2007

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model
Volume 13, Number 12–December 2007
Research

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle andL-type Bovine Spongiform Encephalopathy in a Mouse Model

Thierry Baron,* Anna Bencsik,* Anne-Gaëlle Biacabe,* Eric Morignat,* andRichard A. Bessen†*Agence Française de Sécurité Sanitaire des Aliments–Lyon, Lyon, France; and†Montana State University, Bozeman, Montana, USA

Abstract

Transmissible mink encepholapathy (TME) is a foodborne transmissible spongiform encephalopathy (TSE) of ranch-raised mink; infection with a ruminant TSE has been proposed as the cause, but the precise origin of TME is unknown. To compare the phenotypes of each TSE, bovine-passaged TME isolate and 3 distinct natural bovine spongiform encephalopathy (BSE) agents (typical BSE, H-type BSE, and L-type BSE) were inoculated into an ovine transgenic mouse line (TgOvPrP4). Transgenic mice were susceptible to infection with bovine-passaged TME, typical BSE, and L-type BSE but not to H-type BSE. Based on survival periods, brain lesions profiles, disease-associated prion protein brain distribution, and biochemical properties of protease-resistant prion protein, typical BSE had a distint phenotype in ovine transgenic mice compared to L-type BSE and bovine TME.The similar phenotypic properties of L-type BSE and bovine TME in TgOvPrP4mice suggest that L-type BSE is a much more likely candidate for the origin of TME than is typical BSE.

snip...

Conclusion

These studies provide experimental evidence that the Stetsonville TME agentis distinct from typical BSE but has phenotypic similarities to L-type BSE in TgOvPrP4 mice. Our conclusion is that L-type BSE is a more likely candidate for a bovine source of TME infection than typical BSE. In the scenario that a ruminant TSE is the source for TME infection in mink, this would be a second example of transmission of a TSE from ruminants to non-ruminants under natural conditions or farming practices in addition to transmission of typical BSE to humans, domestic cats, and exotic zoo animals(37). The potential importance of this finding is relevant to L-type BSE, which based on experimental transmission into humanized PrP transgenic mice and macaques, suggests that L-type BSE is more pathogenic for humans than typical BSE (24,38).



http://www.cdc.gov/eid/content/13/12/1887.htm?s_cid=eid1887_e


Transmissible Mink Encephalopathy TME

http://transmissible-mink-encephalopathy.blogspot.com/


USA MAD COW CASES IN ALABAMA AND TEXAS

***PLEASE NOTE***

USA BASE CASE, (ATYPICAL BSE), AND OR TSE (whatever they are calling it today),
please note that both the ALABAMA COW, AND THE TEXAS COW, both were ''H-TYPE'',
personal communication Detwiler et al Wednesday, August 22, 2007 11:52 PM. ...TSS


http://lists.ifas.ufl.edu/cgi-bin/wa.exe?A2=ind0708&L=sanet-mg&T=0&P=19779


P02.35 Molecular Features of the Protease-resistant Prion Protein (PrPres) in H- type BSE

Biacabe, A-G1; Jacobs, JG2; Gavier-Widén, D3; Vulin, J1; Langeveld, JPM2; Baron, TGM1 1AFSSA, France; 2CIDC-Lelystad, Netherlands; 3SVA, Sweden

Western blot analyses of PrPres accumulating in the brain of BSE- infected cattle have demonstrated 3 different molecular phenotypes regarding to the apparent molecular masses and glycoform ratios of PrPres bands. We initially described isolates (H-type BSE) essentially characterized by higher PrPres molecular mass and decreased levels of the diglycosylated PrPres band, in contrast to the classical type of BSE. This type is also distinct from another BSE phenotype named L-type BSE, or also BASE (for Bovine Amyloid Spongiform Encephalopathy), mainly characterized by a low representation of the diglycosylated PrPres band as well as a lower PrPres molecular mass. Retrospective molecular studies in France of all available BSE cases older than 8 years old and of part of the other cases identified since the beginning of the exhaustive surveillance of the disease in 20001 allowed to identify 7 H- type BSE cases, among 594 BSE cases that could be classified as classical, L- or H-type BSE. By Western blot analysis of H-type PrPres, we described a remarkable specific feature with antibodies raised against the C-terminal region of PrP that demonstrated the existence of a more C-terminal cleaved form of PrPres (named PrPres#2 ), in addition to the usual PrPres form (PrPres #1). In the unglycosylated form, PrPres #2 migrates at about 14 kDa, compared to 20 kDa for PrPres #1. The proportion of the PrPres#2 in cattle seems to by higher compared to the PrPres#1. Furthermore another PK–resistant fragment at about 7 kDa was detected by some more N-terminal antibodies and presumed to be the result of cleavages of both N- and C- terminal parts of PrP. These singular features were maintained after transmission of the disease to C57Bl/6 mice. The identification of these two additional PrPres fragments (PrPres #2 and 7kDa band) *** reminds features reported respectively in sporadic Creutzfeldt-Jakob disease and in Gerstmann-Sträussler-Scheinker (GSS) syndrome in humans.


FC5.5.2 Transmission of Italian BSE and BASE Isolates in Cattle Results into a Typical BSE Phenotype and a Muscle Wasting Disease

Zanusso, G1; Lombardi, G2; Casalone, C3; D'Angelo, A4; Gelmetti, D2; Torcoli, G2; Barbieri, I2; Corona, C3; Fasoli, E1; Farinazzo, A1; Fiorini, M1; Gelati, M1; Iulini, B3; Tagliavini, F5; Ferrari, S1; Monaco, S1; Caramelli, M3; Capucci, L2 1University of Verona, Neurological and Visual Sciences, Italy; 2IZSLER, Italy; 3IZSPLVA, Italy; 4University of Turin, Animal Pathology, Italy; 5Isituto Carlo Besta, Italy

The clinical phenotype of bovine spongiform encephalopathy has been extensively reported in early accounts of the disorder. Following the introduction of statutory active surveillance, almost all BSE cases have been diagnosed on a pathological/molecular basis, in a pre-symptomatic clinical stage. In recent years, the active surveillance system has uncovered atypical BSE cases, which are characterized by distinct conformers of the PrPSc, named high-type (BSE-H) and low-type (BSE-L), whose clinicopathological phenotypes remain unknown. We recently reported two Italian atypical cases with a PrPSc type similar to BSE-L, pathologically characterized by PrP amyloid plaques. Experimental transmission to TgBov mice has recently disclosed that BASE is caused by a distinct prion strain which is extremely virulent. A major limitation of transmission studies to mice is the lack of reliable information on clinical phenotype of BASE in its natural host. In the present study, we experimentally infected Fresian/Holstein and Alpine/Brown cattle with Italian BSE and BASE isolates by i.c. route. BASE infected cattle showed survival times significantly shorter than BSE, a finding more readily evident in Fresian/Holstein, and in keeping with previous observations in TgBov mice. Clinically, BSE-infected cattle developed a disease phenotype highly comparable with that described in field BSE cases and in experimentally challenged cattle. On the contrary, BASE-inoculated cattle developed an amyotrophic disorder accompanied by mental dullness. The molecular and neuropathological profiles, including PrP deposition pattern, closely matched those observed in the original cases. This study further confirms that BASE is caused by a distinct prion isolate and discloses a novel disease phenotype in cattle, closely resembling the phenotype previous reported in scrapie-inoculated cattle *** and in some subtypes of inherited and sporadic Creutzfeldt-Jakob disease. Oral Abstracts 14


http://www.prion2007.com/pdf/Prion%20Book%20of%20Abstracts.pdf


Subject: In Confidence - Perceptions of unconventional slow virus diseasesof animals in the USA - APRIL-MAY 1989 - G A H Wells



Gerald Wells: Report of the Visit to USA, April-May 1989

snip...

The general opinion of those present was that BSE, as anovert disease phenomenon, _could exist in the USA, but if it did, it was very rare. The need for improved and specific surveillance methods to detect it as recognised...

snip...

It is clear that USDA have little information and _no_ regulatory responsibility for rendering plants in the US...

snip...

3. Prof. A. Robertson gave a brief account of BSE. The US approach was to accord it a _very low profile indeed_. Dr. A Thiermann showed the picture in the ''Independent'' with cattle being incinerated and thought this was a fanatical incident to be _avoided_ in the US _at all costs_...

snip...please read this old full text document !

http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf


TSS
 
Sandhusker,

The USDA BSE prevalence assumptions are based on stable state dynamics for the sake of ultra-conservative modelling.

"Even though APHIS concludes that decreasing Canadian prevalence is most likely, we
quantitatively analyze the impact of the constant BSE prevalence produced by the BBC
model to simulate potential BSE exposure in U.S. cattle. This calculation provides a
reasonable estimate (and likely an overestimate) of prevalence and subsequent release of
infectivity over the 20 years of the analysis. Using the BBC estimate over this
timeframe, the model estimates release of approximately 19 infected bovines. As an
expression of our uncertainty regarding the application to Canada's prevalence
calculation of the additional UK data on the efficacy of a feed ban, we performed a
sensitivity analysis which excluded this additional information. That more risk-inflating
and less likely scenario results in the importation 108 infected bovines over 20 years."

The admission by the USDA is that BSE prevalence in Canada is most likely decreasing, but the model the USDA uses does not reflect the decrease in prevalence. Please note that this is the USDA's model, not mine. Common sense combined with a study of the dynamics of the British experience would appear to indicate strongly that a ban on the use of RMBM in all animal feed combined with strict SRM removal and disposal protocols must result in a decrease in BSE prevalence.

Flounder,

They say that brevity is the soul of wit.
 
Shaft said:
snip....

Flounder,

They say that brevity is the soul of wit.


yep shaft, i thought were just full of hot air.


and they also say that those that use mathematical formulas construed by the USDA without all the components for that formula are full of shinola.

:tiphat: :wave:


kind regards,
terry
 
Flounder,

Just got back in town. Sorry you took my quote from Shakespeare the wrong way (Polonius, the notorious windbag in Hamlet). My point was that it is difficult, if not impossible, for me to try to understand your points if I am being buried in material. Material that, forgive my ignorance, I have a hard time linking together. My mind, like many others I am afraid, operates best when trying to digest thoughts and ideas one at a time.

Would it be too much to ask if you would be kind enough to sort some of it out and put it in terms I might understand?

For example, we know since the sixties from both Hadlow and Marsh that the existence of TME was confirmed in NA long before the existence of BSE was confirmed. We know now that the source of TME in the Ontario, Stetsonville and other outbreaks may well have been deadstock cattle. We know also that the only three identified cases of atypical BSE in North America (Texas, Alabama and Manitoba) are of the strain identified as H-type. You have provided an abstract from a paper that suggests mink are not susceptible to infection by H-type BSE, and L-type BSE has yet to be found in NA.

Your views?
 
Shaft said:
Flounder,

Just got back in town. Sorry you took my quote from Shakespeare the wrong way (Polonius, the notorious windbag in Hamlet). My point was that it is difficult, if not impossible, for me to try to understand your points if I am being buried in material. Material that, forgive my ignorance, I have a hard time linking together. My mind, like many others I am afraid, operates best when trying to digest thoughts and ideas one at a time.

Would it be too much to ask if you would be kind enough to sort some of it out and put it in terms I might understand?

For example, we know since the sixties from both Hadlow and Marsh that the existence of TME was confirmed in NA long before the existence of BSE was confirmed. We know now that the source of TME in the Ontario, Stetsonville and other outbreaks may well have been deadstock cattle. We know also that the only three identified cases of atypical BSE in North America (Texas, Alabama and Manitoba) are of the strain identified as H-type. You have provided an abstract from a paper that suggests mink are not susceptible to infection by H-type BSE, and L-type BSE has yet to be found in NA.

Your views?



my views that we have been covering up mad cow disease of all strains here for some time.

my views are that these different phenotypes, mixed and or single, are just different routes and sources, from different species, to cause different symptoms and lengths of illness, due to those factors.

my veiws are that both the h-type, l-type BASE, and typical bse, are all here, and have been for some time, and others.

your view, was it typical, atypical, or mixed, the one in Texas that got away ?

FOR IMMEDIATE RELEASE
Statement
May 4, 2004


Media Inquiries: 301-827-6242
Consumer Inquiries: 888-INFO-FDA

Statement on Texas Cow With Central Nervous System Symptoms

On Friday, April 30 th , the Food and Drug Administration learned that a cow with central nervous system symptoms had been killed and shipped to a processor for rendering into animal protein for use in animal feed.

FDA, which is responsible for the safety of animal feed, immediately began an investigation. On Friday and throughout the weekend, FDA investigators inspected the slaughterhouse, the rendering facility, the farm where the animal came from, and the processor that initially received the cow from the slaughterhouse.

FDA's investigation showed that the animal in question had already been rendered into "meat and bone meal" (a type of protein animal feed). Over the weekend FDA was able to track down all the implicated material. That material is being held by the firm, which is cooperating fully with FDA.

Cattle with central nervous system symptoms are of particular interest because cattle with bovine spongiform encephalopathy or BSE, also known as "mad cow disease," can exhibit such symptoms. In this case, there is no way now to test for BSE. But even if the cow had BSE, FDA's animal feed rule would prohibit the feeding of its rendered protein to other ruminant animals (e.g., cows, goats, sheep, bison).


http://www.fda.gov/bbs/topics/news/2004/NEW01061.html

i say this one was BSE, and that's a good thing :roll:
because the last two mad cows in Alabama and Texas that were confirmed
were h-base, which is more like sCJD in studies, and which is more virulent to humans.

what do you call it there shaft, h-base, l-base, bse, and or unknown ???


kind regards,
terrh
 
Flounder,

Given that this is the first I've heard of the 2004 Texas downer, I have no real idea what type BSE it may be, if at all, but my wild guess would be H-type which is known to exist in Texas. If they still have the tissue frozen somewhere, all it takes is the will to find out for sure. Monoclonal antibodies are funny that way.

Where do you get the idea that H-type is more virulent for humans? It is less virulent in cattle, so that seems counter-intuitive.
 

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