Timely article for Mike and TimH

[Mike]

Interesting thoughts Kathy.

I see the research is now leaning towards oxidative stresses being a huge contributing factor to prion diseases.

When you say "oxidative stresses" do you mean like "Free Radicals"?

 

[Kathy]

Yes!

 

[bse-tester]

Case Western Reserve University is also the home of the United States National Prion Surveillance Center. It is also the laboratory where we had our Urine Test confirmed. Mike is all too well aware of the studies being done and writes well on them. As for metal causitives that enhance the probability of prion mutation > Purdey only put forward a hypothesis that has never been proven. It does have merit, but again, it has never been tested to any degree that indicates that it is the causitive trigger. Some people have indicated that his studies may well be based on facts but they are only unproven ideas that do however - before you give me a broadside - warrant further investigation, as would any offering to find causes. Some scientists around the world are doing just that. Personally, I feel that the lack of or overabundance of copper or other base metals has no bearing on the disease or the mutation process of the prion, but I keep an open mind to that question. Further to some of the other comments regarding the SRM removal. I am, and am on record for stating that the removal of SRM's is basically a smoke screen designed, as some suggest, to provide a comfort level to the consumer. The removal of SRM's does nothing to prevent the disease - period. It does however, remove PrPsc from the animal and its product, but it doesn't remove all PrPsc, and that my friends, it the kicker. The buying public needed to be told something to quell their fears and that is the statement that they got, along with the other classic - the 30 month barrier!! God help us when politicians got involved. To state that any animal cannot be infected with BSE if that animal is under the age of 30 months is an absolute dyed in the wool pile of crap!!! The 30 month line in the sand was designed to display an age prior to which the clinical symptoms were NOT LIKELY TO APPEAR due to the lengthy incubation period. Have fun, I am here in the shadows reading from time-to-time.

 

[bse-tester]

Kathy is right in that Dave Brown is currently investigating manganese intrusion in brain and the effect on the normal form of prion. The fact that CJD victims show a huge increase in post-mortem brain examination (8 to 10 times the normal amount of manganese content) leads one to accept the fact that manganese may indeed create a mutation of the prion protein. By replacing the copper content which is essential to normal prion function, the manganese trips the trigger and causes even the most normal and inactive prion to become the abnormal prion. Dave Brown may well be onto the key to identification of the instances of BSE but we shall have to wait and see where he goes with it. The problem in the UK is the high pollution rate of manganese in certain areas of the country and that may be reason enough to seek out whether or not there were any major BSE clusters that can be linked to the higher polluted areas. Interesting concept.

 

[Murgen]

The problem in the UK is the high pollution rate of manganese in certain areas of the country and that may be reason enough to seek out whether or not there were any major BSE clusters that can be linked to the higher polluted areas. Interesting concept.

Did Purdey not already show this in a Eastern European country?

 

[rkaiser]

Sure did Murgen, as well as clusters in other parts of the world. Brown is using some of Mark's initial research and good for him. Mark will always have a more difficult time with recognition due to his occupation and outspoken approach to government and mutinational players.

I'm glad you straightened up the lack of copper vs. the over abundance you spoke of in your first post bse tester. Lack of copper is beleived to be the major factor in the prion identified as the problematic BSE prion.

Met with the Japanese Concul General today and I assure you bse tester, BSE testing is definately still on the agenda for Japanese acceptence. Ever heard of Beef Initiative Group Canada? We have been lobbying government and industry to allow BSE testing for export marketing purposes for over a year now. CBEF is finally on board, and APB, CCA are quietly applauding in the background, so as not to disturb their American mutinational interests. Give me a call sometime, if you can get around the fact that I disagree with feed transmission. :wink:
(403) 946 - 0228 Randy Kaiser

 

[Murgen]

Randy, with your sweet nature, who could hold a little thing like your rejection of feed transmission against you?

AH, that's what I like, Hugs all around!

The Ranchers family is slowly coming together as one! Well, besides the odd ugly sibling.

 

[rkaiser]

I guess that's it then R2. First you sweeten me up and then you bury me with evidence. Or not. Kathy has shown the flaws in the Horn report on numerous occasions, and I will never challenge you article for article. I don't have the energy for that. I beleive what I beleive, and I know I will convince you of nothing.

You're right about me being sweet R2, but damnit all I"M MARRIED for crying out loud. Just stop it. 8)