Recall urged for nutritional supplements after wasting-disease find
By Hanneke Brooymans, Canwest News ServiceApril 3, 2009
EDMONTON - New research shows the infectious prions associated with chronic wasting disease can be found in a substance that's used to make nutritional supplements.
The discovery is prompting one organization to demand an emergency recall of the products, though the Canadian Food Inspection Agency says there's no reason to worry.
Chronic wasting disease, or CWD, is a fatal disease that spreads among species in the deer family. Like mad cow disease, the killer involved is a prion - a tiny, infectious agent that, unlike a virus or bacterium, is made up entirely of protein and contains no nucleic acid.
The new discovery of prions in antler velvet of CWD-afflicted elk suggests this tissue may play a role in disease transmission among members of the deer family, including elk, said the study, which will be published in the Emerging Infectious Diseases Journal in May.
"Humans who consume antler velvet as a nutritional supplement are at risk for exposure to prions," the study said.
The Canadian Food Inspection Agency collaborated on the study with scientists from the University of Kentucky Medical Center, Colorado State University, and the U.S. Department of Agriculture.
The results of the study are not surprising, given that the prions have been found in blood and nervous tissues, and antler velvet is rich in nerves and blood, said Dr. Cornelius Kiley, senior veterinarian with the Canadian Food Inspection Agency.
But Kiley said people who consume nutritional supplements made from antler velvet don't need to worry.
"Based upon the scientific evidence at this time, they should not be concerned."
There is no scientific evidence that CWD is transmissible to humans, he said.
In Alberta and Saskatchewan, all elk over 12 months of age that go to slaughter must be tested for CWD, he explained. Currently, there are no tests for live animals, and velvet comes from live animals.
But Darrel Rowledge, director of the Calgary-based Alliance for Public Wildlife, is convinced these measures aren't enough.
Rowledge, who has followed the CWD issue for 20 years, said his organization is in the midst of drafting a letter to Prime Minister Stephen Harper, asking him to start an emergency recall of all velvet products, both for humans and animals.
Rowledge said it's utterly irresponsible to say there's no evidence the CWD can infect humans.
"An absence of evidence is not evidence of absence," he said, "so we can't prove that it has happened, but that doesn't indicate that it can't happen."
Rowledge noted the prions would not be destroyed in the process used to create the nutritional supplements. One study showed that prions could survive being cooked at 600 C.
Kiley said there are two ongoing studies seeking to get closer to that question of whether or not primates can be infected by CWD. The tests are being done on non-human primates. It will take three to five years before the results are known, because the disease has a long incubation period, he said.
"There is no evidence, but it's only by doing the research, and doing it extensively, where you can start to speak in absolute terms. And the world's not there yet with CWD."
The capsules at the Optimum Health Centre in Edmonton are produced in Alberta, and are used mostly by men to boost testosterone levels, said Elaine Doucette, the store manager.
"We're not at this point going to pull it off the shelf, because we haven't seen a reason to do that."
Edmonton Journal
[email protected]
© Copyright (c) The Edmonton Journal
http://www.canada.com/Health/Recall+urged+nutritional+supplements+after+wasting+disease+find/1462698/story.html
TSS ----- Original Message ----- From: "TERRY SINGELTARY" <
[email protected]> To: <
[email protected]> Sent: Saturday, March 21, 2009 9:41 PM Subject: [BSE-L] Does elk velvet antler relieve arthritic pain? Research study seeks participants
--------------------
[email protected] --------------------
Does elk velvet antler relieve arthritic pain? Research study seeks participants
http://www.ucalgary.ca/gazette/april7-03/elkvelvet.html
Does elk velvet antler relieve arthritic pain?
Research study seeks participants A research study on the use of elk velvet antler in the treatment of rheumatoid arthritis is currently seeking participants in Calgary who suffer from this ailment.
Elk velvet antler is an ancient Chinese remedy that is reputed to have a wide variety of positive physiological effects. Kathy Oberle, a U of C Faculty of Nursing professor, together with colleagues from the University of Alberta, conducted a successful pilot study two years ago and received national funding for the next phase of the research - a randomized controlled clinical trial. About 100 patients from Edmonton have already entered the trial, and the researchers are now seeking participants from the Calgary area.
For people suffering from rheumatoid arthritis, a disease that causes joint swelling and immobility, elk velvet could offer much relief.
"We are excited about the possibility that this might help people control their rheumatoid arthritis symptoms without side effects," says Oberle. "It's on the market now, and many people who take it say it has positive effects. However it has never been subjected to the kind of rigorous scientific testing that health care providers expect. We want to be able to advise patients based on research, not hearsay, so we need people to take part in this controlled trial." The study will test over 200 arthritis patients and give them either elk velvet or placebo pills along with their usual medications. Therefore, the researchers are looking for participants who:
a.. have diagnosed rheumatoid arthritis b.. are still experiencing some symptoms, despite taking standard therapy c.. did not develop their RA in childhood d.. live in the Calgary area Potential participants interested in finding out more about the study can call 1-866-492-6427 or 1-403-220-7863.
Elk velvet is harvested annually from elk livestock on farms. Male elk grow and shed their antlers every year. It is in the early stages of growth, while elk antlers are still velvety in appearance, that the antlers are thought to be most therapeutic. At this time antler tissue is extremely vascular and can grow to more than 40 pounds in just over two months.
http://www.ucalgary.ca/gazette/april7-03/elkvelvet.html
http://www.circare.org/FOIA/hcati2_220228.pdf
http://www.circare.org/FOIA/ephedra4.htm
Greetings,
wonder if these participants are being closely monitored for a TSE ???
IT would seem prudent now, with this recent warning, to take the actions that should have been taken long ago with nutritional supplements.
IT would seem prudent now, to issue this new data on the nutritional supplements web site, it seems to be dead.
http://www.cfsan.fda.gov/~dms/supplmnt.html#dsfl
I find this study most important.
some of us have been saying this for years, myself, i made a submission to the BSE Inquiry in England in 1998. At least they listened.
But i thought some of you would be interested in this.
I don't care really what anybody eats, and or, if you want to pour a gallon of urine on yourself, if it makes you feel good, to go for a hunt. whatever turns you on.
BUT, when you have the CDC finally come out with a warning like this after so many years of floundering, better late than never i suppose, but how many were exposed needlessly???
----- Original Message ----- From: "TERRY SINGELTARY" <
[email protected]> To: <
[email protected]> Sent: Thursday, March 19, 2009 8:47 PM Subject: [CJD-L] Chronic Wasting Disease Prions in Elk Antler Velvet (Nutritional Supplements and CJD)
10.3201/eid1505.081458 Suggested citation for this article: Angers RC, Seward TS, Napier D, Green M, Hoover E, Spraker T, et al. Chronic wasting disease prions in elk antler velvet. Emerg Infect Dis. 2009 May; [Epub ahead of print]
Chronic Wasting Disease Prions in Elk Antler Velvet
Rachel C. Angers,1 Tanya S. Seward, Dana Napier, Michael Green, Edward Hoover, Terry Spraker, Katherine O'Rourke, Aru Balachandran, and Glenn C. Telling Author affiliations: University of Kentucky Medical Center, Lexington, Kentucky, USA (R.C. Angers, T.S. Seward, D. Napier, M. Green, G.C. Telling); Colorado State University, Fort Collins, Colorado, USA (E. Hoover, T. Spraker); US Department of Agriculture, Pullman, Washington, USA (K. O'Rourke); and Canadian Food Inspection Agency, Ottawa, Ontario, Canada (A. Balachandran) 1Current affiliation: MRC Laboratory of Molecular Biology, Cambridge, UK.
Chronic wasting disease (CWD) is a contagious, fatal prion disease of deer and elk that continues to emerge in new locations. To explore the means by which prions are transmitted with high efficiency among cervids, we examined prion infectivity in the apical skin layer covering the growing antler (antler velvet) by using CWD-susceptible transgenic mice and protein misfolding cyclic amplification. Our finding of prions in antler velvet of CWD-affected elk suggests that this tissue may play a role in disease transmission among cervids. Humans who consume antler velvet as a nutritional supplement are at risk for exposure to prions. The fact that CWD prion incubation times in transgenic mice expressing elk prion protein are consistently more rapid raises the possibility that residue 226, the sole primary structural difference between deer and elk prion protein, may be a major determinant of CWD pathogenesis.
snip...
Discussion
Acknowledgments We thank Dongyue Zhuang for excellent technical assistance. This work was supported by grants 2RO1NS040334-04 from the National Institute
http://www.cdc.gov/eid/content/15/5/pdfs/08-1458.pdf
snip...
1998 MY SUBMISSION TO THE BSE INQUIRY ENGLAND
Sender: "Patricia Cantos" <patricia.cantos at bse.org.uk> To: "Terry S Singeltary Sr. (E-mail)" <flounder at wt.net> Subject: Your submission to the Inquiry Date: Fri, 3 Jul 1998 10:10:05 +0100
3 July 1998 Mr Terry S Singeltary Sr. E-Mail: Flounder at wt.net Ref: E2979
Dear Mr Singeltary,
Thank you for your E-mail message of the 30th of June 1998 providing the Inquiry with your further comments. Thank you for offering to provide the Inquiry with any test results on the nutritional supplements your mother was taking before she died.
As requested I am sending you our general Information Pack and a copy of the Chairman's letter. Please contact me if your system cannot read the attachments.
Regarding your question, the Inquiry is looking into many aspects of the scientific evidence on BSE and nvCJD. I would refer you to the transcripts of evidence we have already heard which are found on our internet site at http://www.bse.org.uk. Could you please provide the Inquiry with a copy of the press article you refer to in your e-mail? If not an approximate date for the article so that we can locate it? In the meantime, thank you for you comments. Please do not hesitate to contact me on 0171 261 8332 should you have any queries.
Yours sincerely Patricia Cantos Families Team Leader Attachments TSS
==============
-------- Original Message --------
Subject: re: METABOLIFE AND TSEs GAO-03-494 ''URGENT DATA'' Date: Thu, 01 May 2003 16:04:35 -0400 From: "Marcia G Crosse" <CrosseM at gao.gov> To: <flounder at wt.net> CC: "Charles W Davenport" <DavenportC at gao.gov>, "Carolyn Feis Korman" <FeisKormanC at gao.gov>, "Martin Gahart" <GahartM at gao.gov>
Mr. Singletary,
We were informed by representatives of Metabolife, Inc. that Metabolife 356 was reformulated to remove bovine complex as an ingredient in the product, approximately September 2001. We did not independently verify the contents of the product.
Sincerely, Marcia Crosse Acting Director Health CarePublic Health and Science Issues U.S. General Accounting Office 441 G Street, N.W. Washington, D.C. 20548
===================
-------- Original Message -------- Subject: Re: METABOLIFE AND TSEs GAO-03-494 ''URGENT DATA'' Date: Thu, 01 May 2003 15:48:52 -0500 From: "Terry S. Singeltary Sr." <flounder at wt.net> To: Marcia G Crosse <CrosseM at gao.gov> CC: Charles W Davenport <DavenportC at gao.gov>, Carolyn Feis Korman <FeisKormanC at gao.gov>, Martin Gahart <GahartM at gao.gov> References: <seb14599.014 at GAOGWIA1.GAO.GOV>
THANK YOU!
MIRACLES DO HAPPEN! ;-)
now all we need to do is;
snip......
one small step for man, one giant leap for mankind ;-)
however;
''We did not independently verify the contents of the product''
???
TSS
####### http://mailhost.rz.uni-karlsruhe.de/warc/bse-l.html ########
see history of mad cow in a pill ;
Thursday, March 19, 2009
Chronic Wasting Disease Prions in Elk Antler Velvet (Nutritional Supplements and CJD)
http://chronic-wasting-disease.blogspot.com/2009/03/chronic-wasting-disease-prions-in-elk.html
Wednesday, March 18, 2009
Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay
http://chronic-wasting-disease.blogspot.com/2009/03/detection-of-cwd-prions-in-urine-and.html
RECALLS AND FIELD CORRECTIONS: FOODS CLASS II
___________________________________
PRODUCT
a) Elk Meat, Elk Tenderloin, Frozen in plastic vacuum packaging. Each package is approximately 2 lbs., and each case is approximately 16 lbs.; Item number 755125, Recall # F-129-9;
b) Elk Meat, Elk Trim, Frozen; Item number 755155, Recall # F-130-9;
c) Elk Meat, French Rack, Chilled. Item number 755132, Recall # F-131-9;
d) Elk Meat, Nude Denver Leg. Item number 755122, Recall # F-132-9;
e) Elk Meat, New York Strip Steak, Chilled. Item number 755128, Recall # F-133-9;
f) Elk Meat, Flank Steak Frozen. Item number 755131, Recall # F-134-9;
CODE
Elk Meats with production dates of December 29, 30, and 31
RECALLING FIRM/MANUFACTURER
Recalling Firm: Sierra Meats, Reno, NV, by telephone on January 29, 2009 and press release on February 9, 2009.
Manufacturer: Noah's Ark Holding, LLC, Dawson, MN. Firm initiated recall is ongoing.
REASON
Elk products contain meat derived from an elk confirmed to have Chronic Wasting Disease (CWD).
VOLUME OF PRODUCT IN COMMERCE
Unknown
DISTRIBUTION
NV, CA, TX, CO, NY, UT, FL, OK
___________________________________
http://www.fda.gov/bbs/topics/ENFORCE/2009/ENF01099.html
Monday, February 09, 2009
Exotic Meats USA Announces Urgent Statewide Recall of Elk Tenderloin Because It May Contain Meat Derived From An Elk Confirmed To Have CWD
snip...
Cross-sequence transmission of sporadic Creutzfeldt-Jakob disease creates a new prion strain
Date: August 25, 2007 at 12:42 pm PST
our results raise the possibility that CJD cases classified as VV1 may include cases caused by iatrogenic transmission of sCJD-MM1 prions or food-borne infection by type 1 prions from animals, e.g., chronic wasting disease prions in cervid. In fact, two CJD-VV1 patients who hunted deer or consumed venison have been reported (40, 41). The results of the present study emphasize the need for traceback studies and careful re-examination of the biochemical properties of sCJD-VV1 prions.
http://www.jbc.org/
snip...
Clearly, it is premature to draw firm conclusions about CWD passing naturally into humans, cattle and sheep, but the present results suggest that CWD transmissions to humans would be as limited by PrP incompatibility as transmissions of BSE or sheep scrapie to humans. Although there is no evidence that sheep scrapie has affected humans, it is likely that BSE has caused variant CJD in 74 people (definite and probable variant CJD cases to date according to the UK CJD Surveillance Unit). Given the presumably large number of people exposed to BSE infectivity, the susceptibility of humans may still be very low compared with cattle, which would be consistent with the relatively inefficient conversion of human PrP-sen by PrPBSE. Nonetheless, since humans have apparently been infected by BSE, it would seem prudent to take reasonable measures to limit exposure of humans (as well as sheep and cattle) to CWD infectivity as has been recommended for other animal TSEs.
snip...
http://www.emboj.org/current.shtml
snip
http://www.cdc.gov/ncidod/EID/vol10no6/03-1082.htm
From: TSS (216-119-163-189.ipset45.wt.net) Subject: CWD aka MAD DEER/ELK TO HUMANS ??? Date: September 30, 2002 at 7:06 am PST
From: "Belay, Ermias" To: Cc: "Race, Richard (NIH)" ; ; "Belay, Ermias" Sent: Monday, September 30, 2002 9:22 AM Subject: RE: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS
Dear Sir/Madam, In the Archives of Neurology you quoted (the abstract of which was attached to your email), we did not say CWD in humans will present like variant CJD.
That assumption would be wrong. I encourage you to read the whole article and call me if you have questions or need more clarification (phone: 404-639-3091). Also, we do not claim that "no-one has ever been infected with prion disease from eating venison." Our conclusion stating that we found no strong evidence of CWD transmission to humans in the article you quoted or in any other forum is limited to the patients we investigated.
Ermias Belay, M.D. Centers for Disease Control and Prevention
-----Original Message----- From: Sent: Sunday, September 29, 2002 10:15 AM To: [log in to unmask]">[log in to unmask]; [log in to unmask]">[log in to unmask]; [log in to unmask]">[log in to unmask] Subject: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS
Sunday, November 10, 2002 6:26 PM ......snip........end..............TSS
snip...
full text ;
http://chronic-wasting-disease.blogspot.com/2009/02/exotic-meats-usa-announces-urgent.html
Wednesday, March 18, 2009 Noah's Ark Holding, LLC, Dawson, MN RECALL Elk products contain meat derived from an elk confirmed to have CWD NV, CA, TX, CO, NY, UT, FL, OK RECALLS AND FIELD CORRECTIONS: FOODS CLASS II
http://chronic-wasting-disease.blogspot.com/2009/03/noahs-ark-holding-llc-dawson-mn-recall.html
============================================================
Saturday, January 24, 2009
Bovine Spongiform Encephalopathy h-BSE ATYPICAL USA 2008 Annual Report Research Project: Study of Atypical Bse
Location: Virus and Prion Diseases of Livestock
2008 Annual Report
http://bse-atypical.blogspot.com/2009/01/bovine-spongiform-encephalopathy-h-bse.html
Thursday, December 04, 2008 2:37 PM
"we have found that H-BSE can infect humans."
personal communication with Professor Kong. ...TSS
see full text ;
http://bse-atypical.blogspot.com/2009/02/atypical-bse-north-america-update.html
PRODUCT IN COMMERCE ;
http://www.google.com/search?um=1&ned=us&hl=en&q=antler+velvet+&btnmeta%3Dsearch%3Dsearch=Search+the+Web
Friday, November 30, 2007
CJD QUESTIONNAIRE USA CWRU AND CJD FOUNDATION
snip...
*** NOTE ***
please include venison/sheep/lamb and the bovine to any of the above questions.
example=brain tanning deer/elk hide or any other topics that pertain to transmission of TSEs
_________________________________________________
example=antler velvet nutritional supplements
_________________________________________________
_any_ nutritional supplements??? name/ingredients
_________________________________________________
example=elk/deer brains ie/scrambled, sandwich or otherwise
_________________________________________________
snip...
http://cjdquestionnaire.blogspot.com/
Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518