porker, not sure if you saw this or not ;
Maternal transfer of classical scrapie prion protein via sheep milk
Background 34. The mechanisms for transmission of classical scrapie between
sheep are not fully understood, however there is evidence to suggest that
the risk of transmission is high during the neonatal period15. A study by
VLA is examining whether milk may be a significant route of transmission by
bottle feeding milk collected from ewes genetically susceptible to, and
infected with classical scrapie, to genetically susceptible TSE-free lambs.
Data 35. Early unpublished findings from the study suggest that milk may be
a route of transmission. Post mortem examination of three lambs that were
bottle-fed milk from classical scrapie infected ewes which died early in the
study from intercurrent disease revealed the presence of PrPSc in gut
lymphoid tissue in two lambs. The milk fed to these two lambs was from two
ewes that developed clinical signs of classical scrapie during lactation.
The milk fed to the third lamb was from a ewe with clinical signs of
classical scrapie at the beginning of lactation from which only a relatively
small volume of milk was produced. Somatic cell counts were high in at least
a proportion of the milk collected from the ewes. PrPSc was not found in a
control lamb, which also died from intercurrent disease, that was fed milk
from an uninfected ewe. Implications 36. These data suggest that PrPSc may
be transmitted from ewe to lamb via milk or colostrum. As a full lactation
was fed to the lambs it is not possible to determine whether transmission
occurred via colostrum and/or the subsequent milk. The study is at too early
a stage to assess whether classical scrapie develops as a result of this
exposure, although this should be considered likely.
Data 35. Early unpublished findings from the study suggest that milk may be a route of transmission. Post mortem examination of three lambs that were bottle-fed milk from classical scrapie infected ewes which died early in the study from intercurrent disease revealed the presence of PrPSc in gut lymphoid tissue in two lambs. The milk fed to these two lambs was from two ewes that developed clinical signs of classical scrapie during lactation. The milk fed to the third lamb was from a ewe with clinical signs of classical scrapie at the beginning of lactation from which only a relatively small volume of milk was produced. Somatic cell counts were high in at least a proportion of the milk collected from the ewes. PrPSc was not found in a control lamb, which also died from intercurrent disease, that was fed milk from an uninfected ewe. Implications 36. These data suggest that PrPSc may be transmitted from ewe to lamb via milk or colostrum. As a full lactation was fed to the lambs it is not possible to determine whether transmission occurred via colostrum and/or the subsequent milk. The study is at too early a stage to assess whether classical scrapie develops as a result of this exposure, although this should be considered likely. 15 For example, Foster et al. (1996) Observations on the transmission of scrapie in experiments using embryo transfer. Vet. Rec. 8, 138, 559-562 and Ryder et al. (2004) Demonstration of lateral transmission of scrapie between sheep kept under natural conditions using lymphoid tissue biopsy. Res. Vet. Sci. 76, 211-217.
snip...see full text 15 pages ;
http://www.seac.gov.uk/papers/99-2.pdf
see full text ;
SEAC 99th meeting on Friday 14th December 2007
http://seac992007.blogspot.com/
SCRAPIE USA
http://scrapie-usa.blogspot.com/
NOR-98 ATYPICAL SCRAPIE CASES USA
http://nor-98.blogspot.com/
CREUTZFELDT JAKOB DISEASE MAD COW BASE UPDATE USA
http://cjdmadcowbaseoct2007.blogspot.com/
Transmissible Mink Encephalopathy TME
http://transmissible-mink-encephalopathy.blogspot.com/
CHRONIC WASTING DISEASE
http://chronic-wasting-disease.blogspot.com/
tss
PORKER said:
Study highlights milk BSE risk
By Chris Mercer
BSE
milk
EU to review food hygiene laws
All news for December 2007
2007 - Fears that cows with BSE could pass on the disease to humans via proteins in their milk has gained more credence from a new study, which has encouraged stricter analysis of dairy products.
Scientists working for a Swiss biotech firm, Alicon, say they have managed to detect prion proteins in the milk of cows, as well as that of humans, sheep and goats, for the first time.
Some prions are known to cause brain diseases, such as Mad Cow disease (BSE) and its human variant, CJD.
It is hoped the breakthrough in Switzerland will help scientists to better understand whether the prion proteins responsible for BSE are also present in the cow's milk.
Prions were recently found in both pasteurised and homogenised milk on supermarket shelves, using new analytical equipment from Alicon, but it remained unclear whether those detected were harmful or not.
"In the case of the prion proteins detected, it is highly likely that they were of a normal variety posing no danger to health," said Dr Ralph Zahn, Alicon's head of research.
But, he warned: "So far there has been no scientific basis for assuming that only 'healthy' prion proteins are present in milk and those causing disease were not."
The Alicon team believes the mere presence of normal prions opens the possibility that disease-carrying prions would also be present in milk from an infected cow.
A rapid test to identify prions in milk is now being developed by the firm, which is a spin-off from the Swiss Federal Institute of Technology.
The possibility of BSE being passed to humans via milk has been a genuine concern for several years.
Some evidence suggests there may be a risk, according to the UK Food Standards Agency (FSA), although no direct data from controlled experiments exists.
Milk is the only product available for public consumption that is derived from BSE-susceptible animals over thirty months of age.