snip...
Rod- snip...
We already have a good chance, depending upon who you believe, that one positive Canadian cow already ended up in the US food chain-- But how many more? How many do you think ended up in the Canadian food chain? Especially prior to SRM removal?
====================================
holy usa srms ot, i am trying to keep you honest, it is becoming more difficult, i hope you were kidding about the srms usa vs canada ;
http://ranchers.net/forum/viewtopic.php?t=15807
================================
OT continues;
I know noone wants to talk about this--its a taboo subject--But do you really think our Ag/cattle groups are doing enough to prepare for the long run on BSE- especially if/when folks start showing up with native origin vCJD, like so many of the European countries are now doing? Seems like a new country pops up every few months....
I've said it many times on Agriville-- that I think Canucks should be working much harder and doing much more to find an export market besides the US-- because when something does happen it will be Canada that gets blamed for it....They are the ones with all the high numbers that all the press has been about in the consumer publications-and they'll make a good scapegoat for the government/politicians and packer boys.....
I can just envision 5-6 years from now and the first case of vCJD shows up in California or New York, in a person that has never been out of country...The public will react with a huge outcry like Japan and all the European countries did-and ask how this could happen when the USDA guaranteed their food safety--- President Hillary will blame it on the Bush administration and shoddy food safety of the USDA/Packers--Ag Secretary Brian Schweitzer will condemn and immediately show evidence of it being tied to the Canadian imports....The border will be slammed shut tight (too late- but politics doesn't care, as long as it looks good)...The Democrat controlled Congress will call for investigations and hearings-- with all fingers pointing back at Canada/Johanss/USDA/Packers... :wink:
OT, there you go again oltimer, you got to forget about the ukbsenvcjd only theory. it's been here, envision no more ;
Subject: Monthly Creutzfeldt Jakob Disease statistics Monday 8 January 2007
Date: January 8, 2007 at 7:33 am PST
Monday 8 January 2007 10:16
Department of Health (National)
Monthly Creutzfeldt Jakob Disease statistics
The Department of Health is today issuing the latest information about the numbers of known cases of Creutzfeldt Jakob disease. This includes cases of variant Creutzfeldt Jakob disease (vCJD) - the form of the disease thought to be linked to BSE. The position is as follows:
Definite and probable CJD cases in the UK: As at 5 January 2007
snip...
https://www.gnn.gov.uk/Content/Detail.asp?ReleaseID=254733&NewsAreaID=2
Volume 12, Number 12–December 2006
PERSPECTIVE
On the Question of Sporadic
or Atypical Bovine SpongiformEncephalopathy and
Creutzfeldt-Jakob Disease
Paul Brown,* Lisa M. McShane,† Gianluigi Zanusso,‡ and Linda Detwiler§
http://www.cdc.gov/ncidod/EID/vol12no12/06-0965.htm?s_cid=eid06_0965_e
3:00 Afternoon Refreshment Break, Poster and Exhibit Viewing in the Exhibit
Hall
3:30 Transmission of the Italian Atypical BSE (BASE) in Humanized Mouse
Models Qingzhong Kong, Ph.D., Assistant Professor, Pathology, Case Western Reserve
University
Bovine Amyloid Spongiform Encephalopathy (BASE) is an atypical BSE strain
discovered recently in Italy, and similar or different atypical BSE cases
were also reported in other countries. The infectivity and phenotypes of
these atypical BSE strains in humans are unknown. In collaboration with
Pierluigi Gambetti, as well as Maria Caramelli and her co-workers, we have
inoculated transgenic mice expressing human prion protein with brain
homogenates from BASE or BSE infected cattle. Our data shows that about half
of the BASE-inoculated mice became infected with an average incubation time
of about 19 months; in contrast, none of the BSE-inoculated mice appear to
be infected after more than 2 years. ***These results indicate that BASE is
transmissible to humans and suggest that BASE is more virulent than
classical BSE in humans.
6:30 Close of Day One
http://www.healthtech.com/2007/tse/day1.asp
SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM
1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype
of 'UNKNOWN' strain growing. ...
http://www.cjdsurveillance.com/resources-casereport.html
There is a growing number of human CJD cases, and they were presented last
week in San Francisco by Luigi Gambatti(?) from his CJD surveillance
collection.
He estimates that it may be up to 14 or 15 persons which display selectively
SPRPSC and practically no detected RPRPSC proteins.
http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm
http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf
JOURNAL OF NEUROLOGY
MARCH 26, 2003
RE-Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob
disease in the United States
Email Terry S. Singeltary:
[email protected]
I lost my mother to hvCJD (Heidenhain Variant CJD). I would like to
comment on the CDC's attempts to monitor the occurrence of emerging
forms of CJD. Asante, Collinge et al [1] have reported that BSE
transmission to the 129-methionine genotype can lead to an alternate
phenotype that is indistinguishable from type 2 PrPSc, the commonest
sporadic CJD. However, CJD and all human TSEs are not reportable
nationally. CJD and all human TSEs must be made reportable in every
state and internationally. I hope that the CDC does not continue to
expect us to still believe that the 85%+ of all CJD cases which are
sporadic are all spontaneous, without route/source. We have many TSEs in
the USA in both animal and man. CWD in deer/elk is spreading rapidly and
CWD does transmit to mink, ferret, cattle, and squirrel monkey by
intracerebral inoculation. With the known incubation periods in other
TSEs, oral transmission studies of CWD may take much longer. Every
victim/family of CJD/TSEs should be asked about route and source of this
agent. To prolong this will only spread the agent and needlessly expose
others. In light of the findings of Asante and Collinge et al, there
should be drastic measures to safeguard the medical and surgical arena
from sporadic CJDs and all human TSEs. I only ponder how many sporadic
CJDs in the USA are type 2 PrPSc?
http://www.neurology.org/cgi/eletters/60/2/176#535
Diagnosis and Reporting of Creutzfeldt-Jakob Disease
Singeltary, Sr et al. JAMA.2001; 285: 733-734.
http://jama.ama-assn.org/
BRITISH MEDICAL JOURNAL
BMJ
http://www.bmj.com/cgi/eletters/319/7220/1312/b#EL2
BMJ
http://www.bmj.com/cgi/eletters/320/7226/8/b#EL1
Atypical features of dementia in a patient with
Creutzfeldt-Jakob disease
Maria P¹chalska1ABCDEFG, Henryk Kurzbauer2ABDE, Maria Formiñska-Kapuœcik3ABDE,
Andrzej Urbanik4ABDE, Gra¿yna Bierzyñska-Macyszyn5BDE, Pawe³ W³aszczuk5BDE
1 Institute of Psychology, University of Gdañsk, Gdañsk, Poland
2 Department of Neurology, Ministerial Hospital, Ministry of Internal Affairs and Administration, Cracow, Poland
3 Eye Surgery Clinic, Specialized Ophthalmological Hospital no. 5, Katowice, Poland
4 Department of Radiology, Collegium Medicum, Jagiellonian University, Cracow, Poland
5 Histopathology Section, Department of Morphology, Medical University of Silesia, Katowice, Poland
Summary
Background: This article describes a Polish patient (female, right-handed, age 68 at onset) diagnosed with the
Heidenhain variant of Creutzfeldt-Jakob Disease (HvCJD), characterized clinically by isolated visual
disturbances with no ocular dysfunction prior to the development of myoclonus and other
symptoms of CJD.
Case Report: Nothing in the history pointed to iatrogenic or acquired CJD, and genetic testing ruled out familial
CJD. The neuroradiological picture (MRI) showed non-specifi c features of cerebral atrophy (cortical
and subcortical). An EEG revealed periodic triphasic sharp waves, particularly in the occipital
lobes, and myoclonus occurring synchronically with generalized periodic epileptiform discharges.
Comprehensive neuropsychological testing documented rapidly progressive dementia, with dysgraphia
and aphasia deteriorating to organic mutism. Post-mortem neuropathological examination
confi rmed spongiform encephalopathy, especially in occipital cortex, with amyloid plaques
but without neurofi brillary tangles.
Conclusions: Over the crucial 6-week period the patient went from "Mild Cognitive Impairment" to a status resembling
the fi nal stages of Alzheimer's disease, without any evidence of a CVA. The only aspect
of this case that does not fi t the usual criteria for the Heidenhain variant is the fact that the patient
survived over a year in a persistent vegetative state. Ophthalmologists and family physicians
should be aware of the possibility of HvCJD in any patient over 60 presenting with otherwise inexplicable
visual disturbances in the absence of signifi cant ocular pathology, even when other symptoms
of dementia may not be immediately noticeable.
snip...
CONCLUSIONS
In the case reported here, a clinical diagnosis of the Heidenhain
variant of Creuzfeldt-Jakob Disease, initially suggested by the
early and prominent presentation of visual symptoms (ranging
from microopsia and macropsia to visual hallucinations),
and backed by EEG and neuroadiological fi ndings, was con-
fi rmed by neuropathological results. Neuropsychological testing
documented the characteristically rapid course of the disease.
The course of development of clinical symptoms and
their relationship to the ophthalmological and neuroradiological
picture are of considerable theoretical interest.
Ophthalmologists and family physicians should be aware of
the possibility of HvCJD in any patient over 60 presenting
with otherwise inexplicable visual disturbances in the absence
of signifi cant ocular pathology, even when other symptoms
of dementia may not be immediately noticeable. ...
http://www.medscimonit.com/pub/vol_13/no_1/9923.pdf
Text and figures of the latest annual report of the CJD unit (published 4th December 2006).
FOURTEENTH ANNUAL REPORT 2005
CREUTZFELDT-JAKOB DISEASE
SURVEILLANCE IN THE UK
SUMMARY
The national surveillance programme for Creutzfeldt-Jakob disease (CJD) in the UK was
initiated in May 1990. In 1999, the National CJD Surveillance Unit (NCJDSU) became a
WHO Collaborative Centre for Reference and Research on the surveillance and epidemiology
of human transmissible spongiform encephalopathies (TSEs). In September 2001 the
National Care Team was formed, which currently comprises a care coordinator and a secretary. It
is based within the NCJDSU and was formed in response to concerns regarding the care of CJD
patients.
The information provided in this fourteenth report continues to provide evidence of a high level
of case ascertainment. In last year's report, a decrease in the number of referrals was noted, along
with a drop in the number of recorded sporadic CJD deaths in 2004. This raised concerns about
the completeness of case ascertainment. Further data are now available. While the decline in the
number of referrals has been maintained in 2005, analysis suggests that much, if not all of the
decline is due to changes in the number of referrals who turn out not to be CJD cases. The
number of sporadic cases in 2005 was higher than in 2004 and the data for 2005 may still be
incomplete; thus the present data do not suggest a significant consistent decline in the number of
recorded sporadic CJD deaths (discussed in more detail in Section 2). Detailed clinical and
epidemiological information has been obtained for the great majority of patients. The case-control
study for risk factors of CJD has continued recruitment and initial analysis has been undertaken,
with the results with respect to vCJD published in early 2006. Although there is ongoing evidence
that the post mortem rate for patients with suspected CJD has declined, in line with general
autopsy rates in the UK, it remains high (around 60%). The decline is reflected in the reduced
number of brain specimens examined in the neuropathology laboratory; sporadic CJD numbers
being 52 in 2003, 32 in 2004 and 32 in 2005.
In 1990-2005 mortality rates from sporadic CJD in England, Wales, Scotland and Northern
Ireland were, respectively, 0.89, 1.01, 0.88 and 0.49/million/year. The differences between these
rates are not statistically significant (p>0.5). The variation in the observed mortality rates between
the different regions within the UK is not statistically significant (p>0.3). The highest and lowest
mortality rates from sporadic CJD were observed in the South West (SMR=131) and Northern
Ireland (SMR=67). The mortality rates from sporadic CJD in the UK are comparable to those
observed in most other European countries and elsewhere in the world, including countries that
are free of BSE.
Up to 31 December 2005, there were 153 deaths from definite or probable variant CJD (vCJD) in
the UK. Of these, 110 were confirmed by neuropathology. A further 6 probable cases were alive
as at 31st December 2005. The clinical, neuropathological and epidemiological features of these
cases of vCJD are remarkably uniform and consistent with our previous descriptions. Risk factors
for the development of vCJD include age, residence in the UK and methionine homozygosity at
Section 1
T
Fourteenth Annual Report 2005 4
codon 129 of the prion protein gene - all 139 cases (87%) of vCJD with available genetic analysis
have been methionine homozygotes. The incidence of vCJD is higher in the north of the UK
than in the south. Analysis of the incidence of vCJD onsets and deaths from January 1994 to
December 2005 indicates that a peak has been passed. While this is an encouraging finding, the
incidence of vCJD may increase again, particularly if different genetic subgroups are found but
with longer incubation periods. The identification of disease-related PrP in the spleen of a blood
recipient of PRNP-129 MVgenotype is not inconsistent with such an hypothesis. In addition, this
case along with the report of the prevalence of abnormal PrP in the large study of appendix and
tonsil tissues suggests a possibility of a greater number of preclinical or subclinical cases in the
population than might be indicated by the present numbers of confirmed clinical cases.
The only statistically significant geographic cluster of vCJD cases in the UK was in Leicestershire.
All geographically associated cases of vCJD are considered for investigation according to a
protocol which involves the NCJDSU, colleagues at the HPA, HPS and local public health
physicians.
The activities of the NCJDSU are strengthened by collaboration in other surveillance projects,
including the Transfusion Medicine Epidemiology Review and the study of Progressive
Intellectual and Neurological Deterioration in Children. The collaboration of our colleagues in
these projects is greatly appreciated; the effectiveness of this collaboration allowed the
identification in 2003 of a case of variant CJD associated with blood transfusion and the
identification in 2004 of PrPres in the spleen of a recipient of blood donated by someone
incubating vCJD. In early 2006 a further case of variant CJD associated with blood transfusion
was identified.
The success of the National CJD Surveillance Project continues to depend on the extraordinary
level of co-operation from the neuroscience community and other medical and paramedical staff
throughout the UK. We are particularly grateful to the relatives of patients for their help with this
study.
snip...full text some 40 pages or so ;
http://www.cjd.ed.ac.uk/report14.pdf
Reporting CJD cases to public health departments - Guidance Document. - (updated November 2006)
http://www.cjd.ed.ac.uk/guidance.htm
Incident Reporting Form New version December 2006 (34kB)
http://www.hpa.org.uk/infections/topics_az/cjd/frameworkannex1-Aug2005.doc
VARIANT CREUTZFELDT-JAKOB DISEASE
CURRENT DATA (DECEMBER 2006)
http://www.cjd.ed.ac.uk/vcjdworld.htm
POTENTIAL TREATMENTS FOR CREUTZFELDT-JAKOB DISEASE
Dr RSG Knight, NCJDSU
updated July 2006
http://www.cjd.ed.ac.uk/TREAT.htm
European CJD stats
http://www.eurocjd.ed.ac.uk/allcjd.htm
http://www.eurocjd.ed.ac.uk/sporadic.htm
http://www.eurocjd.ed.ac.uk/genetic.htm
http://www.eurocjd.ed.ac.uk/nvcjd.html
[Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk
Materials for Human Food and Requirement for the Disposition of
Non-Ambulatory Disabled Cattle
http://www.fsis.usda.gov/OPPDE/Comments/03-025IFA/03-025IFA-2.pdf
[Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine
Spongiform Encephalopathy (BSE)
http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf
THE SEVEN SCIENTIST REPORT ***
http://www.fda.gov/ohrms/dockets/dockets/02n0273/02n-0273-EC244-Attach-1.pdf
PAUL BROWN M.D.
http://www.fda.gov/ohrms/dockets/dockets/02n0273/02n-0273-c000490-vol40.pdf
9 December 2005
Division of Dockets Management (RFA-305)
SEROLOGICALS CORPORATION
James J. Kramer, Ph.D.
Vice President, Corporate Operations
http://www.fda.gov/ohrms/dockets/dockets/02n0273/02n-0273-c000383-01-vol35.pdf
Embassy of Japan
http://www.fda.gov/ohrms/dockets/dockets/02n0273/02N-0273-EC240.htm
http://www.cjdfoundation.org/conferencereport.htm
> Tracy Kedzierski followed with a report about the CJD Foundation Family Questionnaire
> which she works tirelessly at conducting.
thanks tracy, glad it finally got done. we know how 'tirelessly' you must have worked ;-)
Subject: [CJDVoice] CJD FOUNDATION QUESTIONNAIRE ???
(what will they find out with this ??? )
Date: Thu, 07 Nov 2002 10:10:53 -0600
From: "Terry S. Singeltary Sr."
Reply-To:
[email protected]
To:
[email protected]
CC:
[email protected]
Greetings Voice,
i send this 'CJD Foundation Questionnaire' and ask the
group, what they suppose will be found out with this ???
with this questionnaire, in my opinion, they don't want
to know what/where the routes and sources of CJDs in the
USA are coming from. NO WONDER they said i was interfering
with there research, there research consist of _not_ finding
out anything other than how it was diagnosed. you folks
judge for yourself. maybe i'm just being an extremist as
some say??? then again, maybe not...TSS
CJD FOUNDATION QUESTIONNAIRE
REPORT FOR DATA BASE OF PATIENTS WITH CREUTZFELDT--JAKOB DISEASE (CJD)
OR OTHER TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES (TSE's)
Name of Patient*:
(not required; if provided, must be with express consent of family member)
Date form filled out: / / (mm/dd/yy)
Person filling out form:
Relationship of person filling out form to patient:
Location where patient died: State: County: City:
Location where patient resided: State: County: City:
Sex of patient: male female unknown
Race of patient: white African-American -- Asian/Pacific Islander
American-Indian/Alaskan Native Other (please identify:
Unknown
Patient's date of birth: (mm/dd/yy)
Age of patient at onset of symptoms:
Date of patient's initial symptoms: (mm/dd/yy)
Age of patient at time of death:
Patient's date of death: (mm/dd/yy)
Duration of illness: months
Was this case referred to the National Prion Disease Pathology
Surveillance Center at Case Western Reserve University in Cleveland,
Ohio? yes no unknown
If yes, by whom was this case referred?
Pathologist -- Neuropathologist -- Neurologist
Other Physician (please identify which kind:
Unknown
Who made initial diagnosis of CJD or other TSE?
Pathologist - Neuropathologist - Neurologist
Other Physician (please identify which kind: )
Unknown
Please describe the clinical neurological presentation of the illness
(list the symptoms or signs):
at onset of the illness:
during the course of illness:
Was an EEG (electroencephalogram) performed? yes -- no -- unknown
If yes,
how long after onset was the EEG performed?
how many times was the EEG performed?
can you indicate the results?
- slow periodic sharp waves (PSW)
- unilateral periodic sharp waves (LSW)
- not reported
- other
Was the cerebrospinal fluid tested for the 14-3-3 protein? yes - no -
unknown
If yes, what was the result? positive - negative - unknown
Was a brain biopsy performed? - yes - no - unknown
If yes, what was the result?_____positive for____
______negative for CJD and other TSE's
______unknown
Was an autopsy performed? yes - no - unknown
If yes, what was the result? _____positive for____
______negative for CJD and other TSE's
______unknown
Was the neuropathology of this case consistent with new variant CJD?
yes - no - unknown
What was the final diagnosis of this case?
___CJD, probably sporadic
___Familial (hereditary) CJD
___Iatrogenic (by infection) CJD; please specify_______________
___Gerstmann-Strausster-Scheinker Syndrome (GSS)
___Fatal Familial Insomnia (FFI)
___Other
___Unknown
* I hereby give consent to the Creutzfeldt-Jakob Disease Foundation,
Inc. to use the above information, including name of patient if
supplied, in connection with activities to promote the research,
education and awareness of Creutzfeldt-Jakob Disease and related
transmissible spongiform encephalopathies.
-4-
END
====================================================
Greetings again CJD Voice,
NOW, compare to the CJD questionnaire i sent through,
and ask yourself why they ask me to remove this from
internet? better yet, ask yourself why the CJD Foundation
in fact did remove my questionnaire from their message
board? what is it they are so afraid of that we may find
out?
Subject: [CJDVoice] CJD QUESTIONNAIRE... updated version II...TSS
Date: Tue, 05 Nov 2002 12:52:52 -0600
From: "Terry S. Singeltary Sr."
Reply-To:
[email protected]
To:
[email protected]
CC:
[email protected]
CJD VICTIM
1. NAME______________________________________
STREET___________________________________
TOWN_____________________________________
phone____________________________________
A. What is the subjects SURNAME____________________________
B. What is the subjects status? ___________________________
(1=suspect/confirmed CJD, 2=hospital control (specify
diagnosis), 3=GP control).
C. If the subject is a (suspect) case, are they alive on the
day of interview?_____(yes or no or not applicable)
D. What is your (respondent's) name?_______________________
(first name, and surname)
What is the relationship to (subject)?________________
address__________________phone________________________
E. DATE OF INTERVIEW__________________________
LOCATION OF INTERVIEW_____________________
F. NAME OF INTERVIEWER________________________
2. SUBJECT INFORMATION
A. SEX___________________
B. BIRTH DATE____________
C. BIRTH PLACE___________ (country, state, county, city)
D. ETHNIC ORIGIN_________
E. MARITAL*DOMESTIC STATUS__________________
(If the subject is female and is/has been married)
record the subjects maiden name if different from current surname.
F. PRESENT HOME ADDRESS_________________________
(ALSO, If deceased, last home address, before subject
became ill?)
G. Is/was subject right or left handed?__________________
F. How many years of full-time education?________________
3. PAST MEDICAL HISTORY
A. Has the Subject had dental treatment other than fillings:
e.g. extractions or root canal work?_________________
If yes, record a description of treatment; with dates;
Dentists name and address____________________________
B. Has the Subject ever had any operations, including eye
operations or stitching of wounds?___________________
(If yes, record the year, hospital and type of operation).
_____________________________________________
_____________________________________________
_____________________________________________
(record total number of operations)
For each type of operation record the number of such operations
undergone, the year of the first such operation and the year of the last
such operation. When no such operations were undergone record 0 for the
number of operations.
NEUROLOGIC (brain)_____________________________
EYE____________________________________________
ABDOMINAL______________________________________
ORTHOPEDIC_____________________________________
OTHER__________________________________________
TONSILS OUT?___________________________________
APPENDIX OUT?__________________________________
ever received an ORGAN TRANSPLANT, including corneal or bone
marrow transplant?_____________________________________
kidney, liver, and other_______________________
C. BLOOD TRANSFUSION__________________________
TRANSFUSION OF ALBUMIN OR IMUNOGLOBULIN________
BLOOD DONOR____________________________________
D. Has Subject ever been admitted to a
Hospital_______________________
E. Has Subject ever been to see psychiatrist (reason and
treatment)_____________________
F. MEDICATIONS, has Subject taken any medications regularly, (if
yes, record the date, name of the medication, the reason for taking it,
and route of administration) prompt for prescription drugs, including
insulin and type.
_______________________________________________________
_______________________________________________________
_______________________________________________________
Prompt for hormone therapy or nutritional supplements including
oral contraceptives and hormone replacement therapy:
_______________________________________________________
_______________________________________________________
_______________________________________________________
Prompt for homeopathic/herbal therapy:
_______________________________________________________
_______________________________________________________
_______________________________________________________
Prompt for eyedrops
_______________________________________________________
SUMMARY OF ABOVE RESPONSES; HAS THE SUBJECT BEEN
EXPOSED TO ONE OF THE MEDICATIONS OF BOVINE OR OVINE
ORIGIN, AND OR ANY DESICCATED ANIMAL ORIGIN?
G. Has Subject ever been tested for allergy using
needles?________________
H. Has Subject ever received a treatment involving a course of
injections?_______________________________________________________
(If yes, record year, name of therapy, frequency, reason)
I. Has Subject been VACCINATED?_______________________________
(If yes, give name of vaccine, and route.)
J. Has Subject ever undergone lumbar puncture or electrical
tests involving needles?________________________________________________
K. Has Subject ever undergone acupuncture?____________________
L. Has Subject ever used drugs by needle?_____________________
M. Has Subject ever been tattooed, ear or body piercing of
anykind?______
4. FAMILY HISTORY PEDIGREE
(indicating years of birth and death) Subjects grandparents,
Subjects parents and parents siblings, Subject and siblings Subjects
children.
A. From the genealogy, record whether the Subject has been
married more than once? ___________________________________________________
B. Have any of the BLOOD relatives of the Subject included in
the Pedigree above died with dementia (or remain alive with
dementia)?_________________________________________________________
C. Have any of these individuals been diagnosed as having
Creutzfeldt-Jakob disease, and or any other T.S.E.?________________
(if so, give name, address, and apprx. date of illness)
D. CONFIRMATION OF FAMILY HISTORY OF CJD OR OTHER TSE'S
(1=definite 2=probable 3=possible 4=unable to confirm 5=not a
case)
_______________________________________________________________
E. Has Subject had social contact, through family, friends or
work, with someone else who developed CJD?_____________________________
(record the persons name and the apprx. date of illness.)
F. Confirmation of social contact with case of CJD?____________
G. FOR NON-U.K. cases only, Has Subject lived in or visited the
United Kingdom during the period 1980-1999?________________________
(if yes, record dat and duration of visits)
DIETARY HISTORY
A. Has Subject ever been a vegetarian for a period of 1 year or
more? (if yes), during what period was Subject vegetarian, and did the
Subject eat any meat or fish at all during this time?______________
B. Does Subject have a history of any other dietary
restrictions or eccentricities? (record apprx. dates and details of
restrictions:
_________________________________________________________
_________________________________________________________
C. How many years did Subject eat school
dinners?__________________
(give dates)
D. Has the Subject ever eaten animal food or pet
food?________________________________________________________
(If yes, record the types of food and dates)
E. How did/does the Subject like their steak
cooked?________________
(1=well done 2=medium 3=medium-rare 4=rare 5=did not eat steak)
F. How often does/did Subject cut or chop up raw red meat or
bones, in their work or in their home?_______________________________
G. (For each of the following food items) How often did Subject
eat (food item)?
BRAIN_________________(specify animal which organ came from)
EYE___________________
TRIPE_________________
LIVER_________________
KIDNEY_______________
SWEETBREADS_________(pancreas)
ROAST LAMB, LAMB COPS, LAMB STEW, ROAST PORK, HAM,
BACON, ROAST BEEF, STEAK, BEEF STEW, MINCED BEEF, VEAL,
VENISON, CHICKEN, BURGERS, MEAT PIES SUCH AS PORK, VEAL,
AND HAM, STEAK AND KIDNEY, CHICKEN AND MUSHROOM,
FAGOTS, MEAT SAUSAGES, BLACK PUDDING, HAGGAS, LIVER
SAUSAGE OR PATE', STEAK TARTARE (raw minced steak with raw egg)
carpaccio, CHEESE, COWS MILK (1=drinks milk/eats breakfast
cereal with milk, 2=only in tea/coffee, 3=NO)_______________________
____________________________________________________________
____________________________________________________________
____________________________________________________________
____________________________________________________________
____________________________________________________________
5. EXPOSURE TO ANIMALS:
A. Did the Subject every HUNT, DRESS, AND EAT,
DEER____________________
ELK_____________________
SQUIRREL_______________
OTHER__________________
(if so, list location, and year, and list any specific organs
that the Subject may have considered to be a delicacy).
B. Did the Subject share a home with:
CATS________________
DOGS________________
FERRETS_____________
C. Has the Subject worked or stayed for more than one week on a
farm? (1=lived or worked, 2=stayed, 3=NO) If YES, did Subject work or
help with;
CATTLE______________
SHEEP________________
GOATS_______________
PIGS__________________
CHICKENS____________
MINK_________________
(If yes), did Subject participate in:
Treating cattle for Warble fly?______________
Dipping sheep?_________________________
Crop Spraying?________________________
(If the Subject took part in any of these activities), record
dates, places and details of the activity including agents
used; ________________________________________________________
________________________________________________________
________________________________________________________
D. Has the Subject used any of the following;
BONEMEAL__________________
HOOF AND HORN____________
DRIED BLOOD________________
MANURE____________________
(if yes, record the item used and dates)
E. Has Subject ever DISSECTED ANIMAL EYES, for example at school?
_________________________________________________________
6. RESIDENTIAL HISTORY (begin with the most recent residence and work
backwards)
From(dd/mm/yy) TO(dd/mm/yy) STREET TOWN COUNTY STATE
(include zip code).
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
7. OCCUPATIONAL HISTORY OF SUBJECT;
(begin with most recent occupation and work backwards)
FROM(dd/mm/yy) TO(dd/mm/yy) NAME OF EMPLOYER TOWN
DESCRIPTION OF WORK;
_________________________________________________________
_________________________________________________________
_________________________________________________________
_________________________________________________________
_________________________________________________________
_________________________________________________________
_________________________________________________________
A. Has the Subject ever worked in farming, the meat industry,
the pharmaceutical industry, or in a hospital?
B. Has the SUBJECT, their PARTNERS or PARENTS ever worked in the
following areas;
medical/pharmaceutical/nursing/dentistry_____________________________
animal laboratories______________________________________________
pharmaceutical laboratories______________________________________
other research laboratories______________________________________
animal farming___________________________________________________
veterinary medicine______________________________________________
meat industry____________________________________________________
(BUTCHER'S/ABATTOIRS/RENDERING PLANTS, ETC) and or
(catering other occupation involving animal products, including
leather)?
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
*** NOTE ***
please include venison/sheep/lamb and the bovine to any of the above
questions.
example=brain tanning deer/elk hide or any other topics
that pertain to transmission of TSEs
_________________________________________________
example=antler velvet nutritional supplements
_________________________________________________
_any_ nutritional supplements??? name/ingredients
_________________________________________________
example=elk/deer brains ie/scrambled, sandwich or otherwise
_________________________________________________
COSMETICS-ie facial creams, eye make-up etc.
name/brand/ingredients
__________________________________________________
MEDICAL-ENDOSCOPY WORK OF ANY TYPE
__________________________________________________
Terry S. Singeltary Sr.
P.O. Box 42
Bacliff, Texas USA 77518
===================================================
Subject: Re: Tracie CJD Foundation
Date: Tue, 5 Nov 2002 15:09:29 -0500
From: "Tracie Kedzierski"
To: "Terry S. Singeltary Sr."
References: <
[email protected]>
<
[email protected]>
<
[email protected]>
<
[email protected]>
<
[email protected]>
Terry,
Oh no....I've gone and pissed you off (ha ha)
I just find it better to speak...so that nothing I write is
misinterpreted. It is very important to me that you understand the
conflict, the confusion, etc so can I call you or not? My dime ?
Tracie
----- Original Message -----
From: "Terry S. Singeltary Sr."
To: "Tracie Kedzierski"
Sent: Tuesday, November 05, 2002 2:45 PM
Subject: Re: Tracie CJD Foundation
> either mail me your explination or forget the it...TSS
>
> Tracie Kedzierski wrote:
>
> > Terry,
> >
> > The only problem is that having it on our messageboard conflicts
> > with the information I have on our home page about the surveillance project
> > and the report form I send out to the families.-----it is confusing. In
> > fact..I'm sorry but we (The Foundation) have to pull it off. I need to talk
> > to you about this and share a number of goals the
> > "new" Foundation has Can I call you? Please email me your number....
> >
> > Tracie
> > Original Message -----
> > From: "Terry S. Singeltary Sr."
> > To: "Tracie Kedzierski"
> > Sent: Tuesday, November 05, 2002 1:34 PM
> > Subject: Re: Tracie CJD Foundation
> >
> >>hi Tracie,
> >>
> >>doing fine, thank you. about the questionnaire?
> >>by no means am i trying to step on Dr Gambetti's toes here.
> >>i think there is more to it than just reporting a case.
> >>we _must_ find the source and route of spordic CJDs, and
> >>i think a great deal of it will be from the medical/surgical
> >>arena. i just want a questionnaire made up for _all_ victims of
> >>human TSEs in the USA in _every_ state, and i want it reportable
> >>in _every_ state. i am turning the heat up. hell, i'm getting
> >>old and grey, i want to see it done before i die. will be sending
> >>this out to many media and papers and requesting them to turn the
> >>heat up on the Gov. you will be able to keep up with the ones
> >>coming through the voice and if i get some that have not come
> >>through the list, i will pass on to Dr. Gambetti if he likes.
> >>i respect Dr. Gambetti very much and would do nothing to hender
> >>his work or yours. i just think that this is too important of
> >>a matter not to have one. and i think by turning the heat up,
> >>getting to the media and pressing there buttons a bit, just
> >>might help this get done a bit faster... hope so anyway...
> >>
> >>kindest regards,
> >>terry
> >>
> >>Tracie Kedzierski wrote:
> >>
> >>
> >>>Hi Terry,
> >>>
> >>>How are you? I'm just curious about your Questionnaire ?
> >>> It just was posted on the Foundation's MessageBoard without any
> >>>introduction... and I was a bit concerned as it may cause some
> > confusion
> >>>with the Surveillance Project I'm doing via the Foundation for Dr
> > Gambetti.
> >
> >>>Could you let me know?
> >>>
> >>>Tracie
Greetings again Voice,
just what is the _new_ CJD Foundations goals with
a CJD Questionnaire that asks _no_ questions about soure/route
of the six variants of sporadic CJDs???
i am reminded of a few things deep throat told me years ago;
============================================================
The most frightening thing I have read all day is the
report of Gambetti's finding of a new strain of
sporadic cjd in young people.........Dear God, what in
the name of all that is holy is that!!!
If the US has different strains of
scrapie.....why????than the UK...then would the same
mechanisms that make different strains of scrapie here
make different strains of BSE...if the patterns are
different in sheep and mice for scrapie.....could not
the BSE be different in the cattle, in the mink, in
the humans.......I really think the slides or tissues
and everything from these young people with the new
strain of sporadic cjd should be put up to be analyzed
by many, many experts in cjd........bse.....scrapie
Scrape the damn slide and put it into
mice.....wait.....chop up the mouse brain and and
spinal cord........put into some more mice.....dammit
amplify the thing and start the damned
research.....This is NOT rocket science...we need to
use what we know and get off our butts and move....the
whining about how long everything takes.....well it
takes a whole lot longer if you whine for a year and
then start the research!!!
Not sure where I read this but it was a recent press
release or something like that:
I thought I would fall out of my chair when I read
about how there was no worry about infectivity from a
histopath slide or tissues because they are preserved
in formic acid, or formalin or formaldehyde.....for
God's sake........ Ask any pathologist in the UK what
the brain tissues in the formalin looks like after a
year.......it is a big fat sponge...the agent
continues to eat the brain ......you can't make slides
anymore because the agent has never stopped........and
the old slides that are stained with Hemolysin and
Eosin......they get holier and holier and degenerate
and continue...what you looked at 6 months ago is not
there........Gambetti better be photographing every
damned thing he is looking at.....
Okay, you need to know. You don't need to pass it on
as nothing will come of it and there is not a damned
thing anyone can do about it. Don't even hint at it
as it will be denied and laughed at..........
USDA is gonna do as little as possible until there is
actually a human case in the USA of the
nvcjd........if you want to move this thing along and
shake the earth....then we gotta get the victims
families to make sure whoever is doing the autopsy is
credible, trustworthy, and a saint with the courage of
Joan of Arc........I am not kidding!!!!
so, unless we get a human death from EXACTLY the same
form with EXACTLY the same histopath lesions as seen
in the UK nvcjd........forget any action........it is
ALL gonna be sporadic!!!
And, if there is a case.......there is gonna be every
effort to link it to international travel,
international food, etc. etc. etc. etc. etc. They
will go so far as to find out if a sex partner had
ever traveled to the UK/europe, etc. etc. ....
It is gonna be a long, lonely, dangerous twisted
journey to the truth. They have all the cards, all
the money, and are willing to threaten and carry out
those threats....and this may be their biggest
downfall...
Thanks as always for your help.
(Recently had a very startling revelation from a rather senior person in
government here..........knocked me out of my chair........you must keep
pushing. If I was a power person....I would be demanding that there be a
least a million bovine tested as soon as possible and agressively
seeking this disease. The big players are coming out of the woodwork as
there is money to be made!!!
In short: "FIRE AT WILL"!!! for the very dumb....who's "will"! "Will
be the burden to bare if there is any coverup!"
again it was said years ago and it should
be taken seriously....BSE will NEVER be found in the
US!
As for the BSE conference call...I think you did a
great service to freedom of information and making
some people feign integrity...I find it scary to see
that most of the "experts" are employed by the federal
government or are supported on the "teat" of federal
funds. A scary picture!
I hope there is a confidential panel organized by the
new government to really investigate this thing.
You need to watch your back........but keep picking at
them.......like a buzzard to the bone...you just may
get to the truth!!! (You probably have more support than
you know. Too many people are afraid to show you or let
anyone else know. I have heard a few things myself...
you ask the questions that everyone else is too afraid to ask.)
================================================================
greetings again voice,
then i remind everyone to read this;
'As implied in the Inset 25 we must not assume that transmission
of BSE to other species will invariably present pathology typical
of a scrapie-like disease.'
http://www.bseinquiry.gov.uk/files/yb/1991/01/04004001.pdf
TSS